[annotation] IMP doc still needs update

Doug Howe dhowe at cs.uoregon.edu
Thu Sep 27 10:21:42 PDT 2007


Thanks Rama,
   It will be great to set the doc straight on this issue.

  -Doug

On Thu, 27 Sep 2007, Rama Balakrishnan wrote:

> I know. Sorry this is taking so long.
> I will work on the document asap.
>
> rama
>
>
> On Sep 27, 2007, at 8:18 AM, Doug Howe wrote:
>
>> Our curators continue to be mislead by the IMP evidence code documentation. 
>> The second bullet states that the following is acceptable usage for IMP.
>> 
>> Overexpression/ectopic expression of wild-type or mutant genes
>> 
>> I think we have all agreed for the better part of a year now that we use 
>> IDA when a wild-type mRNA is introduced into a cell (for example) and 
>> something is deduced from the effect of this.   In contrast we use IMP when 
>> a mutant mRNA, inlcuding a constitutively active mutant mRNA, is introduced 
>> into a cell.
>> 
>> Can I make one final plea that this doc be updated ASAP to reduce curator 
>> confusion.....pleeeeeeaase??
>> 
>> Many thanks,
>>  Doug



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