[annotation] RNA trimethylguanosine cap binding query

[Valerie Wood]

 I recently used the term RNA trimethylguanosine cap binding  
to annotate pombe telomerase RNA and represent the fact that this is 
trimethylguanosine capped, but on re-reading the definition  
I'm not sure if this is correct?
Can I use this for the modification itself?  
or is it for gene products which interact with a capped product?

There do not appear to be any other annotations to this term despite  
the fact that many RNAs are capped which is another reason which made me 
suspect my usage may be wrong.

Should  the binding terms should only be used for non-covalent 
modifications (although this is only in some of the binding defs?), and  
does not represent the use of some terms. For instance GPI anchor 
binding is used for a number of proteins which are GPI anchored, in 
addition to proteins which bins the GPI moiety during GPI anchor 
biosynthesis.

Cheers

Val

Def:
Interacting selectively with the trimethylguanosine (m(3)(2,2,7)-GTP) 
moiety located at the 5' end of some RNA molecules. Such trimethylated 
cap structures, generally produced by posttranscriptional modification 
of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs 
transcribed by RNA polymerase II, but have also be found on snRNAs 
transcribed by RNA polymerase III. They have also been found on a subset 
of the mRNA population in some species, e.g. C. elegans.


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