[Annotation] strange chicken-rabbit mutant hybrid: annotation?

Fiona McCarthy FMcCarthy at cvm.msstate.edu
Tue Jul 1 08:50:32 PDT 2008


Hi All,

I'm annotating a paper about chicken troponin T (PMID:9774396). In one of
the experiments that authors show chicken tropomyosin I (TmI) binding to
rabbit troponin T (TNNT3).

The two functions here are:
GO:0005523 tropomyosin binding for the rabbit TNNT3
GO:0031014 troponin T binding for the chicken TmI

The authors don't mention making a strange mutant hybrid chicken/rabbit (a
raben? a chickbit?) and their intent was to assay binding activity.

Should this be IDA? A chicken protein binding a rabbit protein seems wrong
for IDA.

Fiona

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