[Annotation] phenotype or GO-still struggling

[Doug howe]

I'm still struggling with the issue of whether to make a GO annotation 
(processes in particular) or only phenotype annotation.  The zebrafish 
literature is replete with mutant papers that often describe phenotypes 
involving eyes, otic vesicles, or pharyngeal arches, organ development 
etc.   Often, the IEA annotations for a gene seems to indicate that the 
gene is binding DNA, and may be some sort of transcriptional regulator.  
Should such a gene be annotated with GO terms like 'otic vesicle 
development', or 'eye morphogenesis', or should that be left for 
phenotype annotations?

-- 
Doug Howe, Ph.D.
ZFIN Scientific Curator
Zebrafish Nomenclature Coordinator