[Annotation] evidence code advice

[Rama Balakrishnan]

Hi All,

SGD has come across couple of computationally predicted GO annotation  
data sets for S. cerevisiae that we would like to add to our database.  
The GO annotations from these data sets are predictions based on  
multiple high-throughput data sets. RCA evidence code came to our  
minds but according to the documentation, the annotations all have to  
be manually reviewed by a curator to use this evidence. There are  
several 100 annotations of this kind and it is not feasible for us to  
manually review these annotations.

Hence, we thought these annotations can be bulk loaded with IEA  
evidence code. However, in the Jan 2007 (Cambridge) GO meeting, it was  
decided that the 'with' column information has to be filled in for all  
IEAs (else Mike's filtering script strips them out). But these GO  
annotations being predictions based on multiple high-throughput data  
sets, don't have any information for the with column.  So, we are left  
with no choice.

Which evidence code do people think should be used for these kinds of  
computational datasets when there is not an obvious "with"?

Thanks for your input.


Rama


+-----o--o  
---------------------------------------------------------------
         o-o       Rama Balakrishnan Ph.D
         O          Senior Scientific Curator
       o-o         Saccharomyces Genome Database
      o---o       Stanford University
    o----o        Stanford, CA 94305-5120
  O-----O       Ph: 650.725.8956 Fax: 650.723.7016
    0--o          email: rama at genome.stanford.edu
      O            Website: http://www.yeastgenome.org
     o-o           SGD Wiki- http://wiki.yeastgenome.org
+- o---o  
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