[Annotation] process annotation based on a synthetic peptide?

[Petra Fey]

Hello,

I have a paper (PMID 19121290) where they synthesize a 19 amino acid  
peptide from the EGF-like domain of a Dicty protein (DDB_G0281951),  
they say is secreted (I assume another paper is inprep about this  
protein). They add this peptide to cells that are randomly moving or  
chemotaxing. They find that in both cases the cells move faster. They  
use another synthesized peptide as a negative control, and they use  
two dicty wild type strains. Furthermore they use inhibitors of known  
regulatory pathways of motility and chemotaxis (PI3K and Phospholipase  
A2), which reduces the EGFL-enhanced motility. They conclude "an EGF- 
like peptide", (and discuss, maybe EGFL repeats in general,) "enhances  
cell motility and chemotaxis".

So I wonder, as this is a secreted protein and the peptide in the  
media might mimick the protein's role, is it possible to annotate with  
a chemotaxis or motility term (or the regulation/positive regulation  
term for either/)? And if yes, what evidence code would be used? It's  
part of the protein. IMP? or as it's rather a direct assay, IDA? Or  
can we not extrapolate from the short, synthetic peptide to the  
function of the whole protein?

Thanks,
Petra