[Annotation] filtering IEA translations?

[Doug]

For groups that apply interpro2go, spkw2go, or ec2go translation files:

If a translation from interpro2go for example takes you to a GO term  
which is directly contradictory to an experimentally supported  
annotation in your database, do you apply the IEA annotation or do you  
filter it out?

Example:
	We have an IPI annotation to NOT beta-catenin binding and an IEA  
annotation (translation of InterPro:IPR009428) to 'beta-catenin  
binding' on our lzic gene.  Should such an IEA annotation be made when  
it conflicts with experimental annotations?

I see no problem as long as the evidence code is taken into  
account...what do others think?

-Doug

Doug Howe, Ph.D.
Scientific Curator
Zebrafish Nomenclature Coordinator
Zebrafish Information Network
541-346-0120
dhowe at cs.uoregon.edu