[Annotation] filtering IEA translations?

[Ranjana Kishore]

Hi Doug,
We don't filter out any annotations at this point.  We clearly mark 
annotations as manual or from InterPro2GO mapping or whatever.  Recently 
on our display page, we even made the groupings of "Based on Experiment" 
and "Predicted". 

I don't see a problem as long as evidences are clear, as you point out.

--Ranjana

Doug wrote:
> For groups that apply interpro2go, spkw2go, or ec2go translation files:
>
> If a translation from interpro2go for example takes you to a GO term 
> which is directly contradictory to an experimentally supported 
> annotation in your database, do you apply the IEA annotation or do you 
> filter it out?
>
> Example:
>     We have an IPI annotation to NOT beta-catenin binding and an IEA 
> annotation (translation of InterPro:IPR009428) to 'beta-catenin 
> binding' on our lzic gene.  Should such an IEA annotation be made when 
> it conflicts with experimental annotations?
>
> I see no problem as long as the evidence code is taken into 
> account...what do others think?
>
> -Doug
>
> Doug Howe, Ph.D.
> Scientific Curator
> Zebrafish Nomenclature Coordinator
> Zebrafish Information Network
> 541-346-0120
> dhowe at cs.uoregon.edu
>
>
>
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