cell proliferation (was Re: Growth and development)

[Midori Harris]

There's quite a bit of email on cell proliferation in the list archive 
that should be considered -- the existing definition is the result of a 
longish exchange from 4 years ago, revisited 2 years ago, so it should be 
changed carefully.

m

On Mon, 13 Jun 2005, J Clark wrote:

> Hi Pascale,
> 
> I've put in a new sourceforge request to get comments on that and I'll implement 
> in a week if nobody objects.
> 
> 1219649	cell proliferation
> https://sourceforge.net/tracker/index.php?func=detail&aid=1219649&group_id=36855&atid=440764
> 
> Thanks,
> 
> Jen
> 
> Pascale Gaudet wrote:
> 
> > This all looks good to me.
> > 
> > One other thing is about the definition of cell proliferation, which 
> > currently is "The multiplication or reproduction of cells, resulting in 
> > the rapid expansion of a cell population." Can we remove "rapid"? and 
> > have "The multiplication or reproduction of cells, resulting in the 
> > expansion of a cell population."
> > ??
> > 
> > (this may be relevant for people not on the development list)
> > 
> > Pascale
> > 
> > 
> > At 05:12 PM 6/10/2005 +0100, J Clark wrote:
> > 
> >> Growth and Development proposal:
> >>
> >> 1) The term growth will be moved out from under development to be a 
> >> sibling instead.
> >>
> >> Current structure:
> >>
> >> [i]development
> >> ---[i] growth
> >>
> >> With new structure:
> >>
> >> [i]biological process
> >> ---[i]growth
> >> ---[i]development
> >>
> >> 2) integrate new concepts:
> >>
> >> Term:developmental growth of a unicellular organism
> >> def: The growth of a single celled organism prior to division, where 
> >> growth is aimed at the progression of the organism over time from one 
> >> condition to another.
> >>
> >> term: non-developmental growth of a unicellular organism
> >> def: The growth of a single celled organism prior to division, where 
> >> the growth does not change the organism from  one condition to another 
> >> condition over time.
> >>
> >> Term: developmental growth
> >> def: The increase in size or mass of an entire organism, a part of an 
> >> organism or a cell, where the increase in size or mass is aimed at the 
> >> progression of the organism over time from one condition to another.
> >>
> >> Term: non-developmental growth
> >> def: The increase in size or mass of an entire organism, a part of an 
> >> organism or a cell, where the increase in size or mass is not aimed at 
> >> the progression of the organism over time from one condition to another.
> >>
> >> [i]biological process ; GO:0000004
> >> ---[i]development ; GO:0007275
> >> ------[p]cell development ; GO:0048468
> >> ---------[p]developmental growth of a unicellular organism ; GO:new
> >> ------[p]developmental growth ; GO:new
> >> ---------[i]developmental growth of a unicellular organism ; GO:new
> >> ---[i]growth ; GO:0040007
> >> ------[i]non-developmental growth ; GO:new
> >> ---------[i]non-developmental growth of a unicellular organism ; GO:new
> >> ------[i]developmental growth ; GO:new
> >> ---------[i]developmental growth of a unicellular organism ; GO:new
> >> ------[i]cell growth ; GO:0016049
> >> ---------[i]developmental growth of a unicellular organism ; GO:new
> >> ---------[i]non-developmental growth of a unicellular organism ; GO:new
> >>
> >> also
> >>
> >> [i]cellular physiological process ; GO:0050875
> >> ---[i]cell proliferation ; GO:0008283
> >> ------[p]developmental growth of a unicellular organism ; GO:new
> >> ------[p]non-developmental growth of a unicellular organism ; GO:new
> >>
> >>
> >> This additional parentage means that
> >>
> >> developmental growth of a unicellular organism ; GO:new
> >>
> >> is part_of both
> >>
> >> cell proliferation ; GO:0008283
> >>
> >> and
> >>
> >> cell development ; GO:0048468
> >>
> >> and terms are not allowed to have to part_of parents.
> >> I don't see a way out of that right now.
> >>
> >> Does anybody have any thoughts on that?
> >>
> >> Thanks,
> >>
> >> Jen
> >>
> >>
> >>
> >>
> >>
> > 
> 
> -- 
> EMBL - European Bioinformatics Institute,
> Gene Ontology Consortium,
> and Wolfson College, Cambridge.
> http://www.ebi.ac.uk/~jclark/
>