cell proliferation (was Re: Growth and development)
J Clark
jclark at ebi.ac.uk
Mon Jun 13 05:51:05 PDT 2005
I'll write to the main go list and ask people to check and see if the proposed
change fits with their ideas.
Jen
Midori Harris wrote:
> There's quite a bit of email on cell proliferation in the list archive
> that should be considered -- the existing definition is the result of a
> longish exchange from 4 years ago, revisited 2 years ago, so it should be
> changed carefully.
>
> m
>
> On Mon, 13 Jun 2005, J Clark wrote:
>
>
>>Hi Pascale,
>>
>>I've put in a new sourceforge request to get comments on that and I'll implement
>>in a week if nobody objects.
>>
>>1219649 cell proliferation
>>https://sourceforge.net/tracker/index.php?func=detail&aid=1219649&group_id=36855&atid=440764
>>
>>Thanks,
>>
>>Jen
>>
>>Pascale Gaudet wrote:
>>
>>
>>>This all looks good to me.
>>>
>>>One other thing is about the definition of cell proliferation, which
>>>currently is "The multiplication or reproduction of cells, resulting in
>>>the rapid expansion of a cell population." Can we remove "rapid"? and
>>>have "The multiplication or reproduction of cells, resulting in the
>>>expansion of a cell population."
>>>??
>>>
>>>(this may be relevant for people not on the development list)
>>>
>>>Pascale
>>>
>>>
>>>At 05:12 PM 6/10/2005 +0100, J Clark wrote:
>>>
>>>
>>>>Growth and Development proposal:
>>>>
>>>>1) The term growth will be moved out from under development to be a
>>>>sibling instead.
>>>>
>>>>Current structure:
>>>>
>>>>[i]development
>>>>---[i] growth
>>>>
>>>>With new structure:
>>>>
>>>>[i]biological process
>>>>---[i]growth
>>>>---[i]development
>>>>
>>>>2) integrate new concepts:
>>>>
>>>>Term:developmental growth of a unicellular organism
>>>>def: The growth of a single celled organism prior to division, where
>>>>growth is aimed at the progression of the organism over time from one
>>>>condition to another.
>>>>
>>>>term: non-developmental growth of a unicellular organism
>>>>def: The growth of a single celled organism prior to division, where
>>>>the growth does not change the organism from one condition to another
>>>>condition over time.
>>>>
>>>>Term: developmental growth
>>>>def: The increase in size or mass of an entire organism, a part of an
>>>>organism or a cell, where the increase in size or mass is aimed at the
>>>>progression of the organism over time from one condition to another.
>>>>
>>>>Term: non-developmental growth
>>>>def: The increase in size or mass of an entire organism, a part of an
>>>>organism or a cell, where the increase in size or mass is not aimed at
>>>>the progression of the organism over time from one condition to another.
>>>>
>>>>[i]biological process ; GO:0000004
>>>>---[i]development ; GO:0007275
>>>>------[p]cell development ; GO:0048468
>>>>---------[p]developmental growth of a unicellular organism ; GO:new
>>>>------[p]developmental growth ; GO:new
>>>>---------[i]developmental growth of a unicellular organism ; GO:new
>>>>---[i]growth ; GO:0040007
>>>>------[i]non-developmental growth ; GO:new
>>>>---------[i]non-developmental growth of a unicellular organism ; GO:new
>>>>------[i]developmental growth ; GO:new
>>>>---------[i]developmental growth of a unicellular organism ; GO:new
>>>>------[i]cell growth ; GO:0016049
>>>>---------[i]developmental growth of a unicellular organism ; GO:new
>>>>---------[i]non-developmental growth of a unicellular organism ; GO:new
>>>>
>>>>also
>>>>
>>>>[i]cellular physiological process ; GO:0050875
>>>>---[i]cell proliferation ; GO:0008283
>>>>------[p]developmental growth of a unicellular organism ; GO:new
>>>>------[p]non-developmental growth of a unicellular organism ; GO:new
>>>>
>>>>
>>>>This additional parentage means that
>>>>
>>>>developmental growth of a unicellular organism ; GO:new
>>>>
>>>>is part_of both
>>>>
>>>>cell proliferation ; GO:0008283
>>>>
>>>>and
>>>>
>>>>cell development ; GO:0048468
>>>>
>>>>and terms are not allowed to have to part_of parents.
>>>>I don't see a way out of that right now.
>>>>
>>>>Does anybody have any thoughts on that?
>>>>
>>>>Thanks,
>>>>
>>>>Jen
>>>>
>>>>
>>>>
>>>>
>>>>
>>>
>>--
>>EMBL - European Bioinformatics Institute,
>>Gene Ontology Consortium,
>>and Wolfson College, Cambridge.
>>http://www.ebi.ac.uk/~jclark/
>>
>
>
>
>
--
EMBL - European Bioinformatics Institute,
Gene Ontology Consortium,
and Wolfson College, Cambridge.
http://www.ebi.ac.uk/~jclark/
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