Growth and development

[David Hill]

Hi Jen,

The structure at the bottom looks good to me. I can't really think of 
how to deal with the multiple part-of relationships, but I think they 
are true. As for cell proliferation, I don't think it really matters if 
the word rapid is in the definition or not, since everyone can have a 
different view of rapid. I think the distinction between cell 
proliferation and cell division is a difference between an individual 
cell and a generic representation of cells. In that way, cell division 
could be a part of cell proliferation.


David

J Clark wrote:

> Hi Pascale,
>
> I've put in a new sourceforge request to get comments on that and I'll 
> implement in a week if nobody objects.
>
> 1219649    cell proliferation
> https://sourceforge.net/tracker/index.php?func=detail&aid=1219649&group_id=36855&atid=440764 
>
>
> Thanks,
>
> Jen
>
> Pascale Gaudet wrote:
>
>> This all looks good to me.
>>
>> One other thing is about the definition of cell proliferation, which 
>> currently is "The multiplication or reproduction of cells, resulting 
>> in the rapid expansion of a cell population." Can we remove "rapid"? 
>> and have "The multiplication or reproduction of cells, resulting in 
>> the expansion of a cell population."
>> ??
>>
>> (this may be relevant for people not on the development list)
>>
>> Pascale
>>
>>
>> At 05:12 PM 6/10/2005 +0100, J Clark wrote:
>>
>>> Growth and Development proposal:
>>>
>>> 1) The term growth will be moved out from under development to be a 
>>> sibling instead.
>>>
>>> Current structure:
>>>
>>> [i]development
>>> ---[i] growth
>>>
>>> With new structure:
>>>
>>> [i]biological process
>>> ---[i]growth
>>> ---[i]development
>>>
>>> 2) integrate new concepts:
>>>
>>> Term:developmental growth of a unicellular organism
>>> def: The growth of a single celled organism prior to division, where 
>>> growth is aimed at the progression of the organism over time from 
>>> one condition to another.
>>>
>>> term: non-developmental growth of a unicellular organism
>>> def: The growth of a single celled organism prior to division, where 
>>> the growth does not change the organism from  one condition to 
>>> another condition over time.
>>>
>>> Term: developmental growth
>>> def: The increase in size or mass of an entire organism, a part of 
>>> an organism or a cell, where the increase in size or mass is aimed 
>>> at the progression of the organism over time from one condition to 
>>> another.
>>>
>>> Term: non-developmental growth
>>> def: The increase in size or mass of an entire organism, a part of 
>>> an organism or a cell, where the increase in size or mass is not 
>>> aimed at the progression of the organism over time from one 
>>> condition to another.
>>>
>>> [i]biological process ; GO:0000004
>>> ---[i]development ; GO:0007275
>>> ------[p]cell development ; GO:0048468
>>> ---------[p]developmental growth of a unicellular organism ; GO:new
>>> ------[p]developmental growth ; GO:new
>>> ---------[i]developmental growth of a unicellular organism ; GO:new
>>> ---[i]growth ; GO:0040007
>>> ------[i]non-developmental growth ; GO:new
>>> ---------[i]non-developmental growth of a unicellular organism ; GO:new
>>> ------[i]developmental growth ; GO:new
>>> ---------[i]developmental growth of a unicellular organism ; GO:new
>>> ------[i]cell growth ; GO:0016049
>>> ---------[i]developmental growth of a unicellular organism ; GO:new
>>> ---------[i]non-developmental growth of a unicellular organism ; GO:new
>>>
>>> also
>>>
>>> [i]cellular physiological process ; GO:0050875
>>> ---[i]cell proliferation ; GO:0008283
>>> ------[p]developmental growth of a unicellular organism ; GO:new
>>> ------[p]non-developmental growth of a unicellular organism ; GO:new
>>>
>>>
>>> This additional parentage means that
>>>
>>> developmental growth of a unicellular organism ; GO:new
>>>
>>> is part_of both
>>>
>>> cell proliferation ; GO:0008283
>>>
>>> and
>>>
>>> cell development ; GO:0048468
>>>
>>> and terms are not allowed to have to part_of parents.
>>> I don't see a way out of that right now.
>>>
>>> Does anybody have any thoughts on that?
>>>
>>> Thanks,
>>>
>>> Jen
>>>
>>>
>>>
>>>
>>>
>>
>


-- 
David P. Hill, Ph.D.
Senior Scientific Curator
Gene Expression Database
Gene Ontology Consortium
Mouse Genome Informatics
The Jackson Laboratory
600 Main Street
Bar Harbor, ME 04609-1500
tel:207-288-6430
htpp://www.informatics.jax.org