Growth and development

[Midori Harris]

I think not -- it's better if the current structure does not change. Many 
cell division events take place in contexts that would not be considered 
proliferation (some have been mentioned in the old 'proliferation' 
exchanges).

m

On Thu, 16 Jun 2005, J Clark wrote:

> Hi David,
> 
> Yes I see what you mean.
> 
> Currently we have
> 
> [i]cellular physiological process
> ---[i]cell division
> ---[i]cell proliferation
> 
> cell division
> def: The processes resulting in the physical partitioning 
> and separation of a cell into daughter cells.
> 
> cell proliferation
> def: The multiplication or reproduction of cells, resulting 
> in the rapid expansion of a cell population.
> 
> This could become:
> 
> [i]cellular physiological process
> ---[i]cell proliferation
> ------[p]cell division
> 
> 
> cell proliferation
> def: The multiplication or reproduction of cells, occuring 
> as a consequence of multiple cell division events, resulting 
> in the expansion of a cell population.
> 
> 
> That way we lose the word 'rapid', but keep the distinction 
> between cell division and cell proliferation.
> 
> Would that seem like a plan? I'll post it in the sourceforge 
> item.
> 
> Thanks,
> 
> Jen
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> David Hill wrote:
> 
> > Hi Jen,
> > 
> > The structure at the bottom looks good to me. I can't really think of 
> > how to deal with the multiple part-of relationships, but I think they 
> > are true. As for cell proliferation, I don't think it really matters if 
> > the word rapid is in the definition or not, since everyone can have a 
> > different view of rapid. I think the distinction between cell 
> > proliferation and cell division is a difference between an individual 
> > cell and a generic representation of cells. In that way, cell division 
> > could be a part of cell proliferation.
> > 
> > 
> > David
> > 
> > J Clark wrote:
> > 
> >> Hi Pascale,
> >>
> >> I've put in a new sourceforge request to get comments on that and I'll 
> >> implement in a week if nobody objects.
> >>
> >> 1219649    cell proliferation
> >> https://sourceforge.net/tracker/index.php?func=detail&aid=1219649&group_id=36855&atid=440764 
> >>
> >>
> >> Thanks,
> >>
> >> Jen
> >>
> >> Pascale Gaudet wrote:
> >>
> >>> This all looks good to me.
> >>>
> >>> One other thing is about the definition of cell proliferation, which 
> >>> currently is "The multiplication or reproduction of cells, resulting 
> >>> in the rapid expansion of a cell population." Can we remove "rapid"? 
> >>> and have "The multiplication or reproduction of cells, resulting in 
> >>> the expansion of a cell population."
> >>> ??
> >>>
> >>> (this may be relevant for people not on the development list)
> >>>
> >>> Pascale
> >>>
> >>>
> >>> At 05:12 PM 6/10/2005 +0100, J Clark wrote:
> >>>
> >>>> Growth and Development proposal:
> >>>>
> >>>> 1) The term growth will be moved out from under development to be a 
> >>>> sibling instead.
> >>>>
> >>>> Current structure:
> >>>>
> >>>> [i]development
> >>>> ---[i] growth
> >>>>
> >>>> With new structure:
> >>>>
> >>>> [i]biological process
> >>>> ---[i]growth
> >>>> ---[i]development
> >>>>
> >>>> 2) integrate new concepts:
> >>>>
> >>>> Term:developmental growth of a unicellular organism
> >>>> def: The growth of a single celled organism prior to division, where 
> >>>> growth is aimed at the progression of the organism over time from 
> >>>> one condition to another.
> >>>>
> >>>> term: non-developmental growth of a unicellular organism
> >>>> def: The growth of a single celled organism prior to division, where 
> >>>> the growth does not change the organism from  one condition to 
> >>>> another condition over time.
> >>>>
> >>>> Term: developmental growth
> >>>> def: The increase in size or mass of an entire organism, a part of 
> >>>> an organism or a cell, where the increase in size or mass is aimed 
> >>>> at the progression of the organism over time from one condition to 
> >>>> another.
> >>>>
> >>>> Term: non-developmental growth
> >>>> def: The increase in size or mass of an entire organism, a part of 
> >>>> an organism or a cell, where the increase in size or mass is not 
> >>>> aimed at the progression of the organism over time from one 
> >>>> condition to another.
> >>>>
> >>>> [i]biological process ; GO:0000004
> >>>> ---[i]development ; GO:0007275
> >>>> ------[p]cell development ; GO:0048468
> >>>> ---------[p]developmental growth of a unicellular organism ; GO:new
> >>>> ------[p]developmental growth ; GO:new
> >>>> ---------[i]developmental growth of a unicellular organism ; GO:new
> >>>> ---[i]growth ; GO:0040007
> >>>> ------[i]non-developmental growth ; GO:new
> >>>> ---------[i]non-developmental growth of a unicellular organism ; GO:new
> >>>> ------[i]developmental growth ; GO:new
> >>>> ---------[i]developmental growth of a unicellular organism ; GO:new
> >>>> ------[i]cell growth ; GO:0016049
> >>>> ---------[i]developmental growth of a unicellular organism ; GO:new
> >>>> ---------[i]non-developmental growth of a unicellular organism ; GO:new
> >>>>
> >>>> also
> >>>>
> >>>> [i]cellular physiological process ; GO:0050875
> >>>> ---[i]cell proliferation ; GO:0008283
> >>>> ------[p]developmental growth of a unicellular organism ; GO:new
> >>>> ------[p]non-developmental growth of a unicellular organism ; GO:new
> >>>>
> >>>>
> >>>> This additional parentage means that
> >>>>
> >>>> developmental growth of a unicellular organism ; GO:new
> >>>>
> >>>> is part_of both
> >>>>
> >>>> cell proliferation ; GO:0008283
> >>>>
> >>>> and
> >>>>
> >>>> cell development ; GO:0048468
> >>>>
> >>>> and terms are not allowed to have to part_of parents.
> >>>> I don't see a way out of that right now.
> >>>>
> >>>> Does anybody have any thoughts on that?
> >>>>
> >>>> Thanks,
> >>>>
> >>>> Jen
> >>>>
> >>>>
> >>>>
> >>>>
> >>>>
> >>>
> >>
> > 
> > 
>