Growth and development

[Pascale Gaudet]

Jennifer,

This may be a bit off topic, but how does this term relates to 'cell 
proliferation'? In the case of Dictyostelium, unicellular organism growth 
should probably be a child of cell proliferation (if the definition of cell 
proliferation gets fixed to remove the "rapid expansion" bit).

Pascale


At 03:05 PM 5/24/2005 +0100, J Clark wrote:
>Hi,
>
>I've written to Chris several times over the last few weeks to ask if he 
>agrees with this proposal and I think he must just be too busy to get back 
>to us. In order not to hold things up any longer I propose now to 
>implement the proposal below (previous e-mail) in some form.
>
>Does anybody have any ideas for the term strings and sensu taxa for these 
>terms?
>
>Term: unicellular organism growth prior to division    (sensu x)
>exact_synonym: unicellular organism developmental growth
>prior to division
>def: The growth of single celled organisms, prior to division, for 
>organisms whose research community considers that that kind of growth _is_ 
>part of development.
>
>
>Term: unicellular organism growth prior to division
>(sensu y)
>def: The growth of single celled organisms, prior to division, for 
>organisms whose research community considers that that kind of growth 
>_is_not_ part of development.
>
>
>Thanks,
>
>Jen
>
>
>
>
>
>J Clark wrote:
>
>>Hi,
>>I have rewritten the proposal clarifying the two terms of interest.
>>Does this seem like a better representation?
>>If it does then would Chris be happy with the use of a sensu designation 
>>so high up in the DAG?
>>Thanks,
>>Jen
>>
>>Proposal:
>>Currently we are saying that some species research groups that study 
>>single celled organisms
>>define the relationship between growth and development
>>differently from other species research groups.
>>e.g. one group may say that the growth that occurs prior to
>>  division of the single celled organsim is developmental growth (e.g. 
>> pombe),
>>whilst other research groups say that that kind of growth is
>>not developmental growth (e.g. dicty).
>>The way we're suggesting we'll deal with this is to represent
>>individual instances of growth according to the view of the
>>relevant research community and that we'll clarify things by
>>adding synonyms. If a term 'x growth' needs to have a
>>development parent as well as a growth parent then I add an
>>exact synonym 'x developmental growth'. If a term 'x growth'
>>does not need a development parent then it does not get the
>>synonym. It seems to me that we might also need a sensu term
>>as follows:
>>[i]development
>>---[p]developmental growth
>>------[i]unicellular organism growth prior to division
>>          (sensu x)
>>[i]growth
>>---[i]unicellular organism growth prior to division
>>       (sensu y)
>>---[i]developmental growth
>>
>>Term: unicellular organism growth prior to division
>>       (sensu x)
>>exact_synonym: unicellular organism developmental growth
>>              prior to division
>>def: The growth of single celled organisms, prior to division, for 
>>organisms whose research community considers that that kind of growth 
>>_is_ part of development.
>>
>>Term: unicellular organism growth prior to division
>>       (sensu y)
>>def: The growth of single celled organisms, prior to division, for 
>>organisms whose research community considers that that kind of growth 
>>_is_not_ part of development.
>>
>>
>>
>>
>>
>
>--
>EMBL - European Bioinformatics Institute,
>Gene Ontology Consortium,
>and Wolfson College, Cambridge.
>http://www.ebi.ac.uk/~jclark/