Growth and development

J Clark jclark at ebi.ac.uk
Wed May 25 06:20:43 PDT 2005


Hi Pascale,

Yes that seems like a good plan. I could add that parentage.

Do you think the term string is okay as it is or could we 
have a less clunky version?

Jen

Pascale Gaudet wrote:

> Jennifer,
> 
> This may be a bit off topic, but how does this term relates to 'cell 
> proliferation'? In the case of Dictyostelium, unicellular organism 
> growth should probably be a child of cell proliferation (if the 
> definition of cell proliferation gets fixed to remove the "rapid 
> expansion" bit).
> 
> Pascale
> 
> 
> At 03:05 PM 5/24/2005 +0100, J Clark wrote:
> 
>> Hi,
>>
>> I've written to Chris several times over the last few weeks to ask if 
>> he agrees with this proposal and I think he must just be too busy to 
>> get back to us. In order not to hold things up any longer I propose 
>> now to implement the proposal below (previous e-mail) in some form.
>>
>> Does anybody have any ideas for the term strings and sensu taxa for 
>> these terms?
>>
>> Term: unicellular organism growth prior to division    (sensu x)
>> exact_synonym: unicellular organism developmental growth
>> prior to division
>> def: The growth of single celled organisms, prior to division, for 
>> organisms whose research community considers that that kind of growth 
>> _is_ part of development.
>>
>>
>> Term: unicellular organism growth prior to division
>> (sensu y)
>> def: The growth of single celled organisms, prior to division, for 
>> organisms whose research community considers that that kind of growth 
>> _is_not_ part of development.
>>
>>
>> Thanks,
>>
>> Jen
>>
>>
>>
>>
>>
>> J Clark wrote:
>>
>>> Hi,
>>> I have rewritten the proposal clarifying the two terms of interest.
>>> Does this seem like a better representation?
>>> If it does then would Chris be happy with the use of a sensu 
>>> designation so high up in the DAG?
>>> Thanks,
>>> Jen
>>>
>>> Proposal:
>>> Currently we are saying that some species research groups that study 
>>> single celled organisms
>>> define the relationship between growth and development
>>> differently from other species research groups.
>>> e.g. one group may say that the growth that occurs prior to
>>>  division of the single celled organsim is developmental growth (e.g. 
>>> pombe),
>>> whilst other research groups say that that kind of growth is
>>> not developmental growth (e.g. dicty).
>>> The way we're suggesting we'll deal with this is to represent
>>> individual instances of growth according to the view of the
>>> relevant research community and that we'll clarify things by
>>> adding synonyms. If a term 'x growth' needs to have a
>>> development parent as well as a growth parent then I add an
>>> exact synonym 'x developmental growth'. If a term 'x growth'
>>> does not need a development parent then it does not get the
>>> synonym. It seems to me that we might also need a sensu term
>>> as follows:
>>> [i]development
>>> ---[p]developmental growth
>>> ------[i]unicellular organism growth prior to division
>>>          (sensu x)
>>> [i]growth
>>> ---[i]unicellular organism growth prior to division
>>>       (sensu y)
>>> ---[i]developmental growth
>>>
>>> Term: unicellular organism growth prior to division
>>>       (sensu x)
>>> exact_synonym: unicellular organism developmental growth
>>>              prior to division
>>> def: The growth of single celled organisms, prior to division, for 
>>> organisms whose research community considers that that kind of growth 
>>> _is_ part of development.
>>>
>>> Term: unicellular organism growth prior to division
>>>       (sensu y)
>>> def: The growth of single celled organisms, prior to division, for 
>>> organisms whose research community considers that that kind of growth 
>>> _is_not_ part of development.
>>>
>>>
>>>
>>>
>>>
>>
>> -- 
>> EMBL - European Bioinformatics Institute,
>> Gene Ontology Consortium,
>> and Wolfson College, Cambridge.
>> http://www.ebi.ac.uk/~jclark/
> 
> 
> 

-- 
EMBL - European Bioinformatics Institute,
Gene Ontology Consortium,
and Wolfson College, Cambridge.
http://www.ebi.ac.uk/~jclark/



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