Growth and development

J Clark jclark at ebi.ac.uk
Wed May 25 07:36:56 PDT 2005


Hi,

> "The process by which a cell of a unicellular organism irreversibly 
> increases in size over time by accretion and biosynthetic production of 
> matter similar to that already present, for organisms whose research 
> community considers that this kind of growth _is (not) _ part of development."

Yes that seems good.

> I don't understand why we talk about cell division in there.

I think that was just the example that we started with at 
the meeting. I don't think we need to keep that.

Jen


> 
> At 03:18 PM 5/25/2005 +0100, J Clark wrote:
> 
>> Cool. What d'y think about the defs? Also I guess we use sensu 
>> Dictyosteliida for one but I'm not really sure about the other.
>>
>> How about sensu Schizosaccharomyces? Val said that as a pombe person 
>> she was happy to consider this kind of growth as part of development.
>>
>> Thanks,
>>
>> Jen
>>
>> Pascale Gaudet wrote:
>>
>>> Sounds good to me!
>>> At 02:51 PM 5/25/2005 +0100, J Clark wrote:
>>>
>>>> Hi Pascale,
>>>>
>>>>> I am not sure why we need the 'prior to division' bit??
>>>>
>>>>
>>>>
>>>> True. :-)
>>>>
>>>> 'unicellular organism growth' then?
>>>>
>>>> as a child of 'cell growth'?
>>>>
>>>> Jen
>>>>
>>>>> At 02:20 PM 5/25/2005 +0100, J Clark wrote:
>>>>>
>>>>>> Hi Pascale,
>>>>>>
>>>>>> Yes that seems like a good plan. I could add that parentage.
>>>>>>
>>>>>> Do you think the term string is okay as it is or could we have a 
>>>>>> less clunky version?
>>>>>>
>>>>>> Jen
>>>>>>
>>>>>> Pascale Gaudet wrote:
>>>>>>
>>>>>>> Jennifer,
>>>>>>> This may be a bit off topic, but how does this term relates to 
>>>>>>> 'cell proliferation'? In the case of Dictyostelium, unicellular 
>>>>>>> organism growth should probably be a child of cell proliferation 
>>>>>>> (if the definition of cell proliferation gets fixed to remove the 
>>>>>>> "rapid expansion" bit).
>>>>>>> Pascale
>>>>>>>
>>>>>>> At 03:05 PM 5/24/2005 +0100, J Clark wrote:
>>>>>>>
>>>>>>>> Hi,
>>>>>>>>
>>>>>>>> I've written to Chris several times over the last few weeks to 
>>>>>>>> ask if he agrees with this proposal and I think he must just be 
>>>>>>>> too busy to get back to us. In order not to hold things up any 
>>>>>>>> longer I propose now to implement the proposal below (previous 
>>>>>>>> e-mail) in some form.
>>>>>>>>
>>>>>>>> Does anybody have any ideas for the term strings and sensu taxa 
>>>>>>>> for these terms?
>>>>>>>>
>>>>>>>> Term: unicellular organism growth prior to division    (sensu x)
>>>>>>>> exact_synonym: unicellular organism developmental growth
>>>>>>>> prior to division
>>>>>>>> def: The growth of single celled organisms, prior to division, 
>>>>>>>> for organisms whose research community considers that that kind 
>>>>>>>> of growth _is_ part of development.
>>>>>>>>
>>>>>>>>
>>>>>>>> Term: unicellular organism growth prior to division
>>>>>>>> (sensu y)
>>>>>>>> def: The growth of single celled organisms, prior to division, 
>>>>>>>> for organisms whose research community considers that that kind 
>>>>>>>> of growth _is_not_ part of development.
>>>>>>>>
>>>>>>>>
>>>>>>>> Thanks,
>>>>>>>>
>>>>>>>> Jen
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>> J Clark wrote:
>>>>>>>>
>>>>>>>>> Hi,
>>>>>>>>> I have rewritten the proposal clarifying the two terms of interest.
>>>>>>>>> Does this seem like a better representation?
>>>>>>>>> If it does then would Chris be happy with the use of a sensu 
>>>>>>>>> designation so high up in the DAG?
>>>>>>>>> Thanks,
>>>>>>>>> Jen
>>>>>>>>>
>>>>>>>>> Proposal:
>>>>>>>>> Currently we are saying that some species research groups that 
>>>>>>>>> study single celled organisms
>>>>>>>>> define the relationship between growth and development
>>>>>>>>> differently from other species research groups.
>>>>>>>>> e.g. one group may say that the growth that occurs prior to
>>>>>>>>>  division of the single celled organsim is developmental growth 
>>>>>>>>> (e.g. pombe),
>>>>>>>>> whilst other research groups say that that kind of growth is
>>>>>>>>> not developmental growth (e.g. dicty).
>>>>>>>>> The way we're suggesting we'll deal with this is to represent
>>>>>>>>> individual instances of growth according to the view of the
>>>>>>>>> relevant research community and that we'll clarify things by
>>>>>>>>> adding synonyms. If a term 'x growth' needs to have a
>>>>>>>>> development parent as well as a growth parent then I add an
>>>>>>>>> exact synonym 'x developmental growth'. If a term 'x growth'
>>>>>>>>> does not need a development parent then it does not get the
>>>>>>>>> synonym. It seems to me that we might also need a sensu term
>>>>>>>>> as follows:
>>>>>>>>> [i]development
>>>>>>>>> ---[p]developmental growth
>>>>>>>>> ------[i]unicellular organism growth prior to division
>>>>>>>>>          (sensu x)
>>>>>>>>> [i]growth
>>>>>>>>> ---[i]unicellular organism growth prior to division
>>>>>>>>>       (sensu y)
>>>>>>>>> ---[i]developmental growth
>>>>>>>>>
>>>>>>>>> Term: unicellular organism growth prior to division
>>>>>>>>>       (sensu x)
>>>>>>>>> exact_synonym: unicellular organism developmental growth
>>>>>>>>>              prior to division
>>>>>>>>> def: The growth of single celled organisms, prior to division, 
>>>>>>>>> for organisms whose research community considers that that kind 
>>>>>>>>> of growth _is_ part of development.
>>>>>>>>>
>>>>>>>>> Term: unicellular organism growth prior to division
>>>>>>>>>       (sensu y)
>>>>>>>>> def: The growth of single celled organisms, prior to division, 
>>>>>>>>> for organisms whose research community considers that that kind 
>>>>>>>>> of growth _is_not_ part of development.
>>>>>>>>>
>>>>>>>>>
>>>>>>>>
>>>>>>>> -- 
>>>>>>>> EMBL - European Bioinformatics Institute,
>>>>>>>> Gene Ontology Consortium,
>>>>>>>> and Wolfson College, Cambridge.
>>>>>>>> http://www.ebi.ac.uk/~jclark/
>>>>>>>
>>>>>>>
>>>>>>
>>>>>> -- 
>>>>>> EMBL - European Bioinformatics Institute,
>>>>>> Gene Ontology Consortium,
>>>>>> and Wolfson College, Cambridge.
>>>>>> http://www.ebi.ac.uk/~jclark/
>>>>>
>>>>>
>>>>
>>>> -- 
>>>> EMBL - European Bioinformatics Institute,
>>>> Gene Ontology Consortium,
>>>> and Wolfson College, Cambridge.
>>>> http://www.ebi.ac.uk/~jclark/
>>>
>>>
>>
>> -- 
>> EMBL - European Bioinformatics Institute,
>> Gene Ontology Consortium,
>> and Wolfson College, Cambridge.
>> http://www.ebi.ac.uk/~jclark/

-- 
EMBL - European Bioinformatics Institute,
Gene Ontology Consortium,
and Wolfson College, Cambridge.
http://www.ebi.ac.uk/~jclark/



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