[go-diff] GO update 11/02/2007
Remote CVS for Gene Ontology
gocvs at genome.Stanford.EDU
Fri Nov 2 21:30:46 PDT 2007
OBODIFF of gene_ontology_edit.obo version 5.534 by 5.536
Starting obodiff at /share/go/bin/oboedit/current using 256M of memory
* Created object of type obo:TERM with id GO:0010453
* Created object of type obo:TERM with id GO:0010454
* Created object of type obo:TERM with id GO:0010455
* Created object of type obo:TERM with id GO:0031445
* Created object of type obo:TERM with id GO:0031452
* Created object of type obo:TERM with id GO:0031453
* Created object of type obo:TERM with id GO:0031454
* Created object of type obo:TERM with id GO:0033696
* Created object of type obo:TERM with id GO:0033697
* Created object of type obo:TERM with id GO:0033698
* Created object of type obo:TERM with id GO:0033699
* Populated new object GO:0010453 (macro)
* Changed name of GO:0010453 from "<new term>" to "regulation of cell fate commitment"
* Set definition of GO:0010453 to "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."
* Added definition dbxref GOC:dph to GO:0010453
* Added definition dbxref GOC:tb to GO:0010453
* Copied GO:0010453 to GO:0045165 with type part_of
* Copied GO:0010453 to GO:0045595 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0010453
* Populated new object GO:0010454 (macro)
* Changed name of GO:0010454 from "<new term>" to "negative regulation of cell fate commitment"
* Set definition of GO:0010454 to "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."
* Added definition dbxref GOC:dph to GO:0010454
* Added definition dbxref GOC:tb to GO:0010454
* Copied GO:0010454 to GO:0045596 with type OBO_REL:is_a
* Copied GO:0010454 to GO:0010453 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0010454
* Populated new object GO:0010455 (macro)
* Changed name of GO:0010455 from "<new term>" to "positive regulation of cell fate commitment"
* Set definition of GO:0010455 to "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field."
* Added definition dbxref GOC:dph to GO:0010455
* Added definition dbxref GOC:tb to GO:0010455
* Copied GO:0010455 to GO:0045597 with type OBO_REL:is_a
* Copied GO:0010455 to GO:0010453 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0010455
* Populated new object GO:0031445 (macro)
* Changed name of GO:0031445 from "<new term>" to "regulation of heterochromatin formation"
* Set definition of GO:0031445 to "Any process that modulates the frequency, rate, extent or location of heterochromatin formation."
* Added definition dbxref GOC:mah to GO:0031445
* Copied GO:0031445 to GO:0031507 with type part_of
* Copied GO:0031445 to GO:0033044 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0031445
* Populated new object GO:0031452 (macro)
* Changed name of GO:0031452 from "<new term>" to "negative regulation of heterochromatin formation"
* Set definition of GO:0031452 to "Any process that stops, prevents or reduces the frequency, rate or extent of heterochromatin formation."
* Added definition dbxref GOC:mah to GO:0031452
* Added synonym "down regulation of heterochromatin formation" to GO:0031452
* Changed synonym scope of GO:0031452 from "Related" to "Exact"
* Added synonym "down-regulation of heterochromatin formation" to GO:0031452
* Changed synonym scope of GO:0031452 from "Related" to "Exact"
* Added synonym "downregulation of heterochromatin formation" to GO:0031452
* Changed synonym scope of GO:0031452 from "Related" to "Exact"
* Added synonym "inhibition of heterochromatin formation" to GO:0031452
* Changed synonym scope of GO:0031452 from "Related" to "Narrow"
* Copied GO:0031452 to GO:0031445 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0031452
* Populated new object GO:0031453 (macro)
* Changed name of GO:0031453 from "<new term>" to "positive regulation of heterochromatin formation"
* Set definition of GO:0031453 to "Any process that activates or increases the frequency, rate or extent of heterochromatin formation."
* Added definition dbxref GOC:mah to GO:0031453
* Added synonym "activation of heterochromatin formation" to GO:0031453
* Changed synonym scope of GO:0031453 from "Related" to "Narrow"
* Added synonym "stimulation of heterochromatin formation" to GO:0031453
* Changed synonym scope of GO:0031453 from "Related" to "Narrow"
* Added synonym "up regulation of heterochromatin formation" to GO:0031453
* Changed synonym scope of GO:0031453 from "Related" to "Exact"
* Added synonym "up-regulation of heterochromatin formation" to GO:0031453
* Changed synonym scope of GO:0031453 from "Related" to "Exact"
* Added synonym "upregulation of heterochromatin formation" to GO:0031453
* Changed synonym scope of GO:0031453 from "Related" to "Exact"
* Copied GO:0031453 to GO:0031445 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0031453
* Populated new object GO:0031454 (macro)
* Changed name of GO:0031454 from "<new term>" to "regulation of extent of heterochromatin formation"
* Set definition of GO:0031454 to "Any process that modulates the extent or location of heterochromatin formation."
* Added definition dbxref GOC:mah to GO:0031454
* Added synonym "regulation of heterochromatin spreading" to GO:0031454
* Copied GO:0031454 to GO:0031445 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0031454
* Populated new object GO:0033696 (macro)
* Changed name of GO:0033696 from "<new term>" to "negative regulation of extent of heterochromatin formation"
* Set definition of GO:0033696 to "Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin."
* Added definition dbxref GOC:mah to GO:0033696
* Added synonym "maintenance of heterochromatin boundaries" to GO:0033696
* Added synonym "negative regulation of heterochromatin spreading" to GO:0033696
* Copied GO:0033696 to GO:0031454 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0033696
* Populated new object GO:0033697 (macro)
* Changed name of GO:0033697 from "<new term>" to "positive regulation of extent of heterochromatin formation"
* Set definition of GO:0033697 to "Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin."
* Added definition dbxref GOC:mah to GO:0033697
* Added synonym "positive regulation of heterochromatin spreading" to GO:0033697
* Copied GO:0033697 to GO:0031454 with type OBO_REL:is_a
* Assigned namespace "biological_process" to GO:0033697
* Populated new object GO:0033698 (macro)
* Changed name of GO:0033698 from "<new term>" to "Clr6 histone deacetylase complex I/I'"
* Set definition of GO:0033698 to "A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces
pombe)."
* Added definition dbxref GOC:vw to GO:0033698
* Added definition dbxref PMID:17450151 to GO:0033698
* Copied GO:0033698 to GO:0000118 with type OBO_REL:is_a
* Assigned namespace "cellular_component" to GO:0033698
* Populated new object GO:0033699 (macro)
* Changed name of GO:0033699 from "<new term>" to "DNA 5'-adenosine monophosphate hydrolase activity"
* Set definition of GO:0033699 to "Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus."
* Added definition dbxref GOC:mah to GO:0033699
* Added definition dbxref PMID:16547001 to GO:0033699
* Added definition dbxref PMID:17276982 to GO:0033699
* Added synonym "AMP-removal activity" to GO:0033699
* Added synonym "DNA 5'-adenylate hydrolase activity" to GO:0033699
* Changed synonym scope of GO:0033699 from "Related" to "Exact"
* Added synonym "DNA adenylate hydrolysis activity" to GO:0033699
* Changed synonym scope of GO:0033699 from "Related" to "Broad"
* Added synonym "DNA de-adenylation" to GO:0033699
* Added synonym "DNA deadenylation" to GO:0033699
* Copied GO:0033699 to GO:0035312 with type OBO_REL:is_a
* Assigned namespace "molecular_function" to GO:0033699
* Changed comment from "This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function. To update annotations, consider biological_process term 'ribosome biogenesis and assembly ; GO:0042254' or its children and molecular_function term 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function."
* Changed comment from "This term was made obsolete because it represents gene products. To update annotations, consider molecular_function term 'thiol-disulfide exchange intermediate activity ; GO:0030508'." to "This term was made obsolete because it represents gene products."
* Changed comment from "This term was made obsolete because it describes a substrate-specific process. To update annotations, consider biological_process term 'negative regulation of mitotic recombination ; GO:0045950'." to "This term was made obsolete because it describes a substrate-specific process."
* Changed comment from "This term was made obsolete because it describes a gene product and it contains component information. To update annotations, consider cellular_component term 'plasma membrane ; GO:0005886' or its children and molecular_function term 'long-chain fatty acid transporter activity ; GO:0005324' or its children." to "This term was made obsolete because it describes a gene product and it contains component information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept. To update annotations, consider biological_process terms 'chromosome organization and biogenesis ; GO:0051276' or its children, 'chromosome segregation ; GO:0007059' or its children, and 'DNA replication ; GO:0006260' or its children." to "This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept."
* Changed comment from "This term was made obsolete because it was not defined and the string name implied two separate processes. To update annotations, consider biological_process terms 'barrier septum formation ; GO:0000917' or its children, 'selection of site for barrier septum formation ; GO:0000918', and 'septin ring assembly ; GO:0000921'." to "This term was made obsolete because it was not defined and the string name implied two separate processes."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because more specific children exist. To update annotations, consider cellular_component terms 'cytosolic large ribosomal subunit (sensu Bacteria) ; GO:0009282' and 'cytosolic large ribosomal subunit (sensu Eukaryota) ; GO:0005842'." to "This term was made obsolete because more specific children exist."
* Changed comment from "This term was made obsolete because more specific children exist. To update annotations, consider cellular_component terms 'cytosolic small ribosomal subunit (sensu Bacteria) ; GO:0009283' and 'cytosolic small ribosomal subunit (sensu Eukaryota) ; GO:0005843'." to "This term was made obsolete because more specific children exist."
* Changed comment from "This term was made obsolete because it represents a biological process and a molecular function. To update annotations, consider biological_process terms 'modification-dependent protein catabolic process ; GO:0019941' or its children and 'protein ubiquitination during ubiquitin-dependent protein catabolic process ; GO:0042787' and molecular_function term 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it represents a biological process and a molecular function."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, consider cellular_component term 'proton-transporting two-sector ATPase complex ; GO:0016469' or its children." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'condensed nuclear chromosome ; GO:0000794' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'condensed chromosome ; GO:0000793' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'nuclear chromosome ; GO:0000228' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'cytoplasmic chromosome ; GO:0000229' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-isoleucine transmembrane transporter activity ; GO:0015188', 'L-valine transmembrane transporter activity ; GO:0005304', and 'sodium:amino acid symporter activity ; GO:0005283' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it contains component and function information. To update annotations, use cellular_component term 'intracellular ; GO:0005622' and molecular_function term 'nucleoside transmembrane transporter activity ; GO:0005337'." to "This term was made obsolete because it contains component and function information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'sodium-transporting ATPase activity, rotational mechanism ; GO:0046962'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider cellular_component term 'heterotrimeric G-protein complex ; GO:0005834' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider cellular_component term 'heterotrimeric G-protein complex ; GO:0005834' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider cellular_component term 'heterotrimeric G-protein complex ; GO:0005834' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable. To update annotations, use biological_process term 'cellular morphogenesis during conjugation with cellular fusion ; GO:0000753'." to "This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process terms 'entry into host ; GO:0044409' or its children and 'growth or development of symbiont within host ; GO:0044412' or its children." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because it is an amalgamation of its two children. To update annotations, consider biological_process terms 'neurotransmitter biosynthetic process ; GO:0042136' or its children and 'sequestering of neurotransmitter ; GO:0042137'." to "This term was made obsolete because it is an amalgamation of its two children."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'microfibril ; GO:0001527' or its children and molecular_function term 'calcium ion binding ; GO:0005509'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'oxygen transporter activity ; GO:0005344'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a group of molecular functions. To update annotations, consider biological_process terms 'proteoglycan metabolic process ; GO:0006029' or its children and 'sulfur metabolic process ; GO:0006790' or its children and molecular_function term 'proteoglycan sulfotransferase activity ; GO:0050698'." to "This term was made obsolete because it represents a group of molecular functions."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'extracellular matrix constituent conferring elasticity ; GO:0030023'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'extracellular matrix constituent conferring elasticity ; GO:0030023'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it is redundant with other terms; obsoleted as part of the metabolism rearrangements. To update annotations, use biological_process terms 'cell growth ; GO:0016049' and 'metabolic process ; GO:0008152'." to "This term was made obsolete because it is redundant with other terms; obsoleted as part of the metabolism rearrangements."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to protozoan ; GO:0001562'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider biological_process term 'heterophilic cell adhesion ; GO:0007157' or its children and molecular_function term 'galactoside binding ; GO:0016936'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because the function it represents does not exist. To update annotations, consider molecular_function term 'apelin receptor binding ; GO:0031704'." to "This term was made obsolete because the function it represents does not exist."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'axonemal dynein complex ; GO:0005858'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'axonemal dynein complex ; GO:0005858'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'axonemal dynein complex ; GO:0005858'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'axonemal dynein complex ; GO:0005858'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'cytoplasmic dynein complex ; GO:0005868'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'cytoplasmic dynein complex ; GO:0005868'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'cytoplasmic dynein complex ; GO:0005868'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'cytoplasmic dynein complex ; GO:0005868'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'intermediate filament ; GO:0005882'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'intermediate filament ; GO:0005882'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'intermediate filament ; GO:0005882'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'type III intermediate filament ; GO:0045098'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins. To update annotations, consider biological_process term 'compound eye photoreceptor development ; GO:0042051' or its children." to "This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins."
* Deleted GO:0001981 --OBO_REL:is_a--> GO:0003018
* Copied GO:0001981 to GO:0003018 with type part_of
* Deleted GO:0003078 --OBO_REL:is_a--> GO:0030147
* Copied GO:0003078 to GO:0030147 with type part_of
* Changed comment from "This term was made obsolete because it represents two functions. To update annotations, use molecular_function terms 'chromatin binding ; GO:0003682' and 'lamin binding ; GO:0005521'." to "This term was made obsolete because it represents two functions."
* Changed comment from "This term was made obsolete because it includes a process term. To update annotations, consider molecular_function term 'damaged DNA binding ; GO:0003684' or its children." to "This term was made obsolete because it includes a process term."
* Changed comment from "This term was made obsolete because it includes a process term. To update annotations, consider molecular_function term 'damaged DNA binding ; GO:0003684' or its children." to "This term was made obsolete because it includes a process term."
* Changed comment from "This term was made obsolete because it does not represent a true molecular function. To update annotations, consider biological_process term 'DNA replication ; GO:0006260' or its children." to "This term was made obsolete because it does not represent a true molecular function."
* Changed comment from "This term was made obsolete because it refers to component information. To update annotations, consider cellular_component term 'extrachromosomal circular DNA ; GO:0005727' or its children and molecular_function term 'DNA binding ; GO:0003677' or its children." to "This term was made obsolete because it refers to component information."
* Changed comment from "This term was made obsolete because sequestering is a process rather than a function. To update annotations, use biological_process term 'cytoplasmic sequestering of transcription factor ; GO:0042994'." to "This term was made obsolete because sequestering is a process rather than a function."
* Changed comment from "This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to. To update annotations, consider molecular_function term 'RNA cap binding ; GO:0000339' or its children." to "This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to."
* Changed comment from "This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to. To update annotations, consider molecular_function term 'RNA cap binding ; GO:0000339' or its children." to "This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to."
* Changed comment from "This term was made obsolete because it describes a cellular component rather than a molecular function. To update annotations, use cellular_component term 'ribonucleoprotein complex ; GO:0030529'." to "This term was made obsolete because it describes a cellular component rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a cellular component rather than a molecular function. To update annotations, use cellular_component term 'small nuclear ribonucleoprotein complex ; GO:0030532'." to "This term was made obsolete because it describes a cellular component rather than a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a single molecular function. To update annotations, use biological_process term 'regulation of progression through cell cycle ; GO:0000074'." to "This term was made obsolete because it does not represent a single molecular function."
* Changed comment from "This term was made obsolete because, as defined, it represents a class of gene products rather than a molecular function. The term string is also ambiguous, having connotations of involvement in transport processes. To update annotations, consider biological_process term 'protein folding ; GO:0006457' or its children and molecular_function term 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because, as defined, it represents a class of gene products rather than a molecular function. The term string is also ambiguous, having connotations of involvement in transport processes."
* Changed comment from "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. To update annotations, consider biological_process term 'protein folding ; GO:0006457' or its children and molecular_function term 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. To update annotations, consider biological_process terms 'chromatin assembly or disassembly ; GO:0006333' or its children and 'nucleosome assembly ; GO:0006334' or its children and molecular_function terms 'histone binding ; GO:0042393' or its children and 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. To update annotations, use molecular_function term 'ATPase activity, coupled ; GO:0042623' and consider biological_process term 'protein folding ; GO:0006457' or its children." to "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information."
* Changed comment from "This term was made obsolete because it represents a class of gene products rather than a molecular function. To update annotations, consider biological_process term 'protein folding ; GO:0006457' or its children and molecular_function term 'chaperone binding ; GO:0051087'." to "This term was made obsolete because it represents a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products rather than a molecular function. To update annotations, consider biological_process term 'protein folding ; GO:0006457' or its children and molecular_function term 'chaperone binding ; GO:0051087'." to "This term was made obsolete because it represents a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products rather than a molecular function. To update annotations, consider biological_process terms 'protein refolding ; GO:0042026' and 'response to unfolded protein ; GO:0006986' or its children." to "This term was made obsolete because it represents a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it includes cellular component information. To update annotations, consider cellular_component term 'axoneme ; GO:0005930' or its children and molecular_function term 'microtubule motor activity ; GO:0003777' or its children." to "This term was made obsolete because it includes cellular component information."
* Changed comment from "This term was made obsolete because it includes anatomy information. To update annotations, use molecular_function term 'microfilament motor activity ; GO:0000146' and consider biological_process term 'muscle contraction ; GO:0006936' or its children and cellular_component term 'contractile fiber ; GO:0043292' or its children." to "This term was made obsolete because it includes anatomy information."
* Changed comment from "This term was made obsolete because it represents a combination of molecular functions. To update annotations, use molecular_function terms 'actin filament binding ; GO:0051015' and 'protein binding, bridging ; GO:0030674'." to "This term was made obsolete because it represents a combination of molecular functions."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'actin filament bundle formation ; GO:0051017'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, use biological_process term 'barbed-end actin filament capping ; GO:0051016'." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, use biological_process term 'barbed-end actin filament capping ; GO:0051016'." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it describes two biological processes. To update annotations, use biological_process terms 'actin filament severing ; GO:0051014' and 'barbed-end actin filament capping ; GO:0051016'." to "This term was made obsolete because it describes two biological processes."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'actin filament depolymerization ; GO:0030042'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because sequestering is a process, not an activity. To update annotations, use biological_process term 'sequestering of actin monomers ; GO:0042989'." to "This term was made obsolete because sequestering is a process, not an activity."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, use biological_process term 'actin filament severing ; GO:0051014'." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it does not make sense. To update annotations, consider biological_process term 'actin cytoskeleton organization and biogenesis ; GO:0030036' or its children." to "This term was made obsolete because it does not make sense."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'membrane ; GO:0016020' or its children and molecular_function term 'actin binding ; GO:0003779' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because the concept belongs in the process ontology. To update annotations, use biological_process term 'regulation of actin filament length ; GO:0030832'." to "This term was made obsolete because the concept belongs in the process ontology."
* Changed comment from "This term was made obsolete because it refers to involvement in a biological process. To update annotations, consider biological_process term 'defense response ; GO:0006952' or its children." to "This term was made obsolete because it refers to involvement in a biological process."
* Changed comment from "This term was made obsolete because it refers to involvement in a biological process. To update annotations, consider biological_process term 'acute-phase response ; GO:0006953' or its children." to "This term was made obsolete because it refers to involvement in a biological process."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'defense response ; GO:0006952' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'defense response to bacterium ; GO:0042742' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'male-specific defense response to bacterium ; GO:0050831' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'defense response to fungus ; GO:0050832' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it refers to involvement in a biological process. To update annotations, consider biological_process term 'response to virus ; GO:0009615' or its children." to "This term was made obsolete because it refers to involvement in a biological process."
* Changed comment from "This term was made obsolete because it refers to involvement in a biological process. To update annotations, consider biological_process term 'blood coagulation ; GO:0007596' or its children and molecular_function term 'serine-type endopeptidase activity ; GO:0004252' or its children." to "This term was made obsolete because it refers to involvement in a biological process."
* Changed comment from "This term was made obsolete because it refers to involvement in a biological process. To update annotations, consider biological_process term 'complement activation ; GO:0006956' or its children." to "This term was made obsolete because it refers to involvement in a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. To update annotations, consider cellular_component term 'MHC class I protein complex ; GO:0042612'." to "This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity."
* Changed comment from "This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. To update annotations, consider cellular_component term 'MHC class II protein complex ; GO:0042613'." to "This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity."
* Changed comment from "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase I complex ; GO:0005736'. To update annotations, use molecular_function term 'DNA-directed RNA polymerase activity ; GO:0003899'." to "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase I complex ; GO:0005736'."
* Changed comment from "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase II, core complex ; GO:0005665'. To update annotations, use molecular_function term 'DNA-directed RNA polymerase activity ; GO:0003899'." to "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase II, core complex ; GO:0005665'."
* Changed comment from "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase III complex ; GO:0005666'. To update annotations, use molecular_function term 'DNA-directed RNA polymerase activity ; GO:0003899'." to "This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase III complex ; GO:0005666'."
* Changed comment from "This term was made obsolete because it represents a gene product and contains cellular component information. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it represents a gene product and contains cellular component information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process terms 'synaptic vesicle uncoating ; GO:0016191' and 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a cellular component. To update annotations, use cellular_component term 'heterotrimeric G-protein complex ; GO:0005834' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it represents a cellular component."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process terms 'synaptic vesicle uncoating ; GO:0016191' and 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process term 'protein import into nucleus ; GO:0006606' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process term 'regulation of cell growth ; GO:0001558' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process term 'cytoskeleton organization and biogenesis ; GO:0007010' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process term 'secretion ; GO:0046903' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it refers to a bifunctional gene product. To update annotations, consider molecular_function terms 'hydrogen ion transporting ATP synthase activity, rotational mechanism ; GO:0046933' and 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'." to "This term was made obsolete because it refers to a bifunctional gene product."
* Changed comment from "This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'. To update annotations, use molecular_function term 'RNA-directed DNA polymerase activity ; GO:0003964'." to "This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'."
* Changed comment from "This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'. To update annotations, use molecular_function term 'RNA-directed DNA polymerase activity ; GO:0003964'." to "This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'plasma membrane ; GO:0005886' or its children and molecular_function term 'cation-transporting ATPase activity ; GO:0019829' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider molecular_function term 'metal ion transmembrane transporter activity ; GO:0046873' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. To update annotations, consider cellular_component term 'ATP-binding cassette (ABC) transporter complex ; GO:0043190' or its children and molecular_function term 'ATPase activity, coupled to transmembrane movement of substances ; GO:0042626' or its children." to "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping."
* Changed comment from "This term was made obsolete because it represents a gene product which can catalyze two reactions. To update annotations, consider molecular_function terms 'nucleoside-diphosphatase activity ; GO:0017110' or its children and 'nucleoside-triphosphatase activity ; GO:0017111' or its children." to "This term was made obsolete because it represents a gene product which can catalyze two reactions."
* Changed comment from "This term was made obsolete because it represents a multistep reaction. To update annotations, use biological_process term 'spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase ; GO:0050983'." to "This term was made obsolete because it represents a multistep reaction."
* Changed comment from "This term was made obsolete because it represents two molecular functions. To update annotations, consider molecular_function terms 'ecdysteroid UDP-glucosyltransferase activity ; GO:0050488' and 'ecdysteroid UDP-glucuronosyltransferase activity ; GO:0050489'." to "This term was made obsolete because it represents two molecular functions."
* Changed comment from "This term was made obsolete because it includes biological process information. To update annotations, use molecular_function term 'caspase activity ; GO:0030693' and consider biological_process term 'apoptosis ; GO:0006915' or its children." to "This term was made obsolete because it includes biological process information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it includes biological process information. To update annotations, use molecular_function term 'caspase activity ; GO:0030693' and consider biological_process term 'apoptosis ; GO:0006915' or its children." to "This term was made obsolete because it includes biological process information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'caspase activity ; GO:0030693'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'lysosome ; GO:0005764' or its children and molecular_function term 'cysteine-type endopeptidase activity ; GO:0004197' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'mitochondrion ; GO:0005739' or its children and molecular_function term 'mitochondrial processing peptidase activity ; GO:0004240'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'mitochondrion ; GO:0005739' or its children and molecular_function term 'mitochondrial processing peptidase activity ; GO:0004240'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'vacuole ; GO:0005773' or its children and molecular_function term 'carboxypeptidase C activity ; GO:0004186'." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it mentions a component term in the text string. To update annotations, consider molecular_function terms 'endopeptidase activity ; GO:0004175' or its children and 'peptidase activity ; GO:0008233' or its children." to "This term was made obsolete because it mentions a component term in the text string."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'ferroxidase activity ; GO:0004322' and 'iron ion transmembrane transporter activity ; GO:0005381' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a process rather than a function. To update annotations, use biological_process term 'glycine decarboxylation via glycine cleavage system ; GO:0019464'." to "This term was made obsolete because it represents a process rather than a function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a function. To update annotations, consider biological_process term 'cell adhesion ; GO:0007155' or its children, cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms 'cell adhesion molecule binding ; GO:0050839' or its children, 'guanylate kinase activity ; GO:0004385', and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product and not a function."
* Changed comment from "This term was made obsolete because it is not a valid molecular function. To update annotations, consider molecular_function term '1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308'." to "This term was made obsolete because it is not a valid molecular function."
* Changed comment from "This term was made obsolete because it is not a valid molecular function. To update annotations, consider molecular_function term '1-phosphatidylinositol-4-phosphate 5-kinase activity ; GO:0016308'." to "This term was made obsolete because it is not a valid molecular function."
* Removed comment
* Removed comment
* Changed comment from "This term was made obsolete because the existence of this function has not been established. To update annotations, consider molecular_function term 'inositol trisphosphate phosphatase activity ; GO:0046030' or its children." to "This term was made obsolete because the existence of this function has not been established."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function terms 'cyclosporin A binding ; GO:0016018' and 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it represents component and function information. To update annotations, use cellular_component term 'extracellular region ; GO:0005576' and molecular_function term 'phospholipase A2 activity ; GO:0004623'." to "This term was made obsolete because it represents component and function information."
* Changed comment from "This term was made obsolete because it represents component and function information. To update annotations, use cellular_component term 'extracellular region ; GO:0005576' and molecular_function term 'calcium-dependent phospholipase A2 activity ; GO:0047498'." to "This term was made obsolete because it represents component and function information."
* Changed comment from "This term was made obsolete because it represents component and function information. To update annotations, use cellular_component term 'cytosol ; GO:0005829' and molecular_function term 'phospholipase A2 activity ; GO:0004623'." to "This term was made obsolete because it represents component and function information."
* Changed comment from "This term was made obsolete because it represents component and function information. To update annotations, use cellular_component term 'cytosol ; GO:0005829' and molecular_function term 'calcium-dependent phospholipase A2 activity ; GO:0047498'." to "This term was made obsolete because it represents component and function information."
* Changed comment from "This term was made obsolete because it represents component and function information. To update annotations, use cellular_component term 'cytosol ; GO:0005829' and molecular_function term 'calcium-independent phospholipase A2 activity ; GO:0047499'." to "This term was made obsolete because it represents component and function information."
* Changed comment from "This term was made obsolete because it represents a gene product, and because the gene was named after its location of action rather than after its molecular function. To update annotations, use molecular_function term 'protein-tyrosine kinase activity ; GO:0004713'." to "This term was made obsolete because it represents a gene product, and because the gene was named after its location of action rather than after its molecular function."
* Changed comment from "This term was made obsolete because the function is covered by an existing term. To update annotations, consider molecular_function term 'superoxide dismutase activity ; GO:0004784' or its children." to "This term was made obsolete because the function is covered by an existing term."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider molecular_function term 'serine-type endopeptidase inhibitor activity ; GO:0004867' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it describes the receptor type, and not an activity. To update annotations, consider molecular_function term 'antigen binding ; GO:0003823' or its children." to "This term was made obsolete because it describes the receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it describes a receptor type, and not an activity. To update annotations, consider molecular_function terms 'MHC class Ib receptor activity ; GO:0032394', 'MHC class II receptor activity ; GO:0032395', and 'peptide antigen binding ; GO:0042605' or its children." to "This term was made obsolete because it describes a receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it represents gene products involved in the biological process of cell adhesion. To update annotations, consider biological_process term 'cell adhesion ; GO:0007155' or its children, cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms 'carbohydrate binding ; GO:0030246' or its children, 'cell adhesion molecule binding ; GO:0050839' or its children, 'protein binding ; GO:0005515' or its children, and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents gene products involved in the biological process of cell adhesion."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function terms 'ciliary neurotrophic factor receptor activity ; GO:0004897' or its children, 'hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity ; GO:0005062' or its children, 'interleukin-11 receptor activity ; GO:0004921', and 'interleukin-6 receptor activity ; GO:0004915'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product rather than an activity. To update annotations, consider molecular_function terms 'boss receptor activity ; GO:0008288', 'non-G-protein coupled 7TM receptor activity ; GO:0004926', and 'transmembrane receptor protein tyrosine kinase activity ; GO:0004714' or its children." to "This term was made obsolete because it represents a gene product rather than an activity."
* Changed comment from "This term was made obsolete because it represents a gene product rather than an activity. To update annotations, use molecular_function term 'Wnt receptor activity ; GO:0042813' and consider biological_process term 'Wnt receptor signaling pathway ; GO:0016055' or its children." to "This term was made obsolete because it represents a gene product rather than an activity."
* Changed comment from "This term was made obsolete because it represents a gene product rather than an activity. To update annotations, use molecular_function term 'Wnt receptor activity ; GO:0042813' and consider biological_process term 'Wnt receptor signaling pathway, calcium modulating pathway ; GO:0007223' or its children." to "This term was made obsolete because it represents a gene product rather than an activity."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'protein binding ; GO:0005515' or its children and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of receptor rather than an activity. To update annotations, consider molecular_function term 'ErbB-3 class receptor binding ; GO:0043125'." to "This term was made obsolete because it represents a class of receptor rather than an activity."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'signal transduction ; GO:0007165' or its children and molecular_function terms 'growth factor binding ; GO:0019838' or its children, 'neurotrophin binding ; GO:0043121' or its children, and 'transmembrane receptor protein tyrosine kinase activity ; GO:0004714' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'signal transduction ; GO:0007165' or its children and molecular_function terms 'nerve growth factor binding ; GO:0048406', 'neurotrophin-3 binding ; GO:0048404', and 'transmembrane receptor protein tyrosine kinase activity ; GO:0004714' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'signal transduction ; GO:0007165' or its children and molecular_function terms 'brain-derived neurotrophic factor binding ; GO:0048403', 'neurotrophin-3 binding ; GO:0048404', 'neurotrophin-4/5 binding ; GO:0048405', and 'transmembrane receptor protein tyrosine kinase activity ; GO:0004714' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'signal transduction ; GO:0007165' or its children and molecular_function terms 'neurotrophin-3 binding ; GO:0048404' and 'transmembrane receptor protein tyrosine kinase activity ; GO:0004714' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a protein family rather than a molecular function. To update annotations, consider molecular_function term 'tumor necrosis factor receptor activity ; GO:0005031'." to "This term was made obsolete because it represents a protein family rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes the receptor type, and not an activity. To update annotations, consider molecular_function term 'CD154 receptor binding ; GO:0042615'." to "This term was made obsolete because it describes the receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it describes the receptor type, and not an activity. To update annotations, consider molecular_function term 'CD70 receptor binding ; GO:0042614'." to "This term was made obsolete because it describes the receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'death receptor binding ; GO:0005123' and 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'death receptor binding ; GO:0005123' and 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'death receptor binding ; GO:0005123' and 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents cellular component and molecular function information. To update annotations, use cellular_component term 'endoplasmic reticulum ; GO:0005783' and molecular_function term 'receptor activity ; GO:0004872'." to "This term was made obsolete because it represents cellular component and molecular function information."
* Changed comment from "This term was made obsolete because it describes a cellular component. To update annotations, consider cellular_component term 'peroxisome ; GO:0005777' or its children and molecular_function term 'receptor activity ; GO:0004872' or its children." to "This term was made obsolete because it describes a cellular component."
* Changed comment from "This term was made obsolete because it describes a cellular component. To update annotations, consider cellular_component term 'peroxisomal membrane ; GO:0005778' or its children and molecular_function term 'receptor activity ; GO:0004872' or its children." to "This term was made obsolete because it describes a cellular component."
* Changed comment from "This term was made obsolete because it represents a cellular component and not a molecular function. To update annotations, use cellular_component term 'heterotrimeric G-protein complex ; GO:0005834'." to "This term was made obsolete because it represents a cellular component and not a molecular function."
* Changed comment from "This term was made obsolete because it names a family of gene products. To update annotations, use molecular_function term 'transforming growth factor beta receptor, common-partner cytoplasmic mediator activity ; GO:0030616'." to "This term was made obsolete because it names a family of gene products."
* Changed comment from "This term was made obsolete because it names a family of gene products. To update annotations, use molecular_function term 'transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ; GO:0030617'." to "This term was made obsolete because it names a family of gene products."
* Changed comment from "This term was made obsolete because it represents a family of gene products. To update annotations, use molecular_function term 'transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ; GO:0030618'." to "This term was made obsolete because it represents a family of gene products."
* Changed comment from "This term was made obsolete because it represents a combination of process and function information. To update annotations, use biological_process term 'protein localization ; GO:0008104' and molecular_function term 'mitogen-activated protein kinase binding ; GO:0051019'." to "This term was made obsolete because it represents a combination of process and function information."
* Changed comment from "This term was made obsolete because it represents a combination of process and function information. To update annotations, use biological_process term 'protein localization ; GO:0008104' and molecular_function term 'protein kinase A binding ; GO:0051018'." to "This term was made obsolete because it represents a combination of process and function information."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider molecular_function term 'ephrin receptor binding ; GO:0046875'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider cellular_component term 'anchored to plasma membrane ; GO:0046658' or its children and molecular_function term 'ephrin receptor binding ; GO:0046875'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider cellular_component term 'integral to plasma membrane ; GO:0005887' or its children and molecular_function term 'ephrin receptor binding ; GO:0046875'." to "This term was made obsolete because it refers to a class of gene products."
* Removed comment
* Changed comment from "This term was made obsolete because it describes a type of hormone rather than a molecular function. To update annotations, consider molecular_function term 'hormone activity ; GO:0005179' or its children." to "This term was made obsolete because it describes a type of hormone rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a type of hormone rather than a molecular function. To update annotations, consider molecular_function term 'hormone activity ; GO:0005179' or its children." to "This term was made obsolete because it describes a type of hormone rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a type of hormone rather than a molecular function. To update annotations, consider molecular_function term 'hormone activity ; GO:0005179' or its children." to "This term was made obsolete because it describes a type of hormone rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a cellular location rather than a function. To update annotations, use molecular_function term 'nutrient reservoir activity ; GO:0045735'." to "This term was made obsolete because it describes a cellular location rather than a function."
* Changed comment from "This term was made obsolete because it represents gene products involved in the biological process of cell adhesion. To update annotations, consider biological_process term 'cell adhesion ; GO:0007155' or its children, cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms 'carbohydrate binding ; GO:0030246' or its children, 'cell adhesion molecule binding ; GO:0050839' or its children, 'protein binding ; GO:0005515' or its children, and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents gene products involved in the biological process of cell adhesion."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider cellular_component term 'collagen ; GO:0005581' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it describes localization and modification rather than activity. To update annotations, consider molecular_function term 'extracellular matrix structural constituent ; GO:0005201' or its children." to "This term was made obsolete because it describes localization and modification rather than activity."
* Changed comment from "This term was made obsolete because it does not describe a molecular function. To update annotations, consider molecular_function term 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it does not describe a molecular function."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, consider molecular_function term 'inward rectifier potassium channel activity ; GO:0005242' or its children." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'amino acid transmembrane transporter activity ; GO:0015171' and external ontology term 'amino acid permease activity ; GO:0015359'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-tryptophan transmembrane transporter activity ; GO:0015196' or its children, 'L-tyrosine transmembrane transporter activity ; GO:0005302', 'L-valine transmembrane transporter activity ; GO:0005304', and 'transmembrane transporter activity ; GO:0022857' or its children and external ontology term 'permease activity ; GO:0015646'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'dicarboxylic acid transmembrane transporter activity ; GO:0005310' or its children, 'organic acid:sodium symporter activity ; GO:0005343' or its children, and 'tricarboxylic acid transmembrane transporter activity ; GO:0015142' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Removed comment
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function term 'lipid transporter activity ; GO:0005319' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'lipid transporter activity ; GO:0005319'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'lipid transporter activity ; GO:0005319'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'lipid transporter activity ; GO:0005319'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'metal ion transmembrane transporter activity ; GO:0046873' or its children and 'secondary active transmembrane transporter activity ; GO:0015291' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'plasma membrane ; GO:0005886' or its children and molecular_function term 'copper ion transmembrane transporter activity ; GO:0005375' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, use cellular_component term 'intracellular ; GO:0005622' and molecular_function term 'copper ion transmembrane transporter activity ; GO:0005375'." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because its meaning was ambiguous, it was undefined and its position in the tree wrong. To update annotations, consider biological_process term 'negative regulation of potassium ion transport ; GO:0043267'." to "This term was made obsolete because its meaning was ambiguous, it was undefined and its position in the tree wrong."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'peroxisome ; GO:0005777' or its children and molecular_function term 'transporter activity ; GO:0005215' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it does not provide a useful functional classification. To update annotations, consider molecular_function term 'transporter activity ; GO:0005215' or its children." to "This term was made obsolete because it does not provide a useful functional classification."
* Changed comment from "This term was made obsolete because it represents a biological process and not a molecular function. To update annotations, use biological_process term 'vacuole organization and biogenesis ; GO:0007033'." to "This term was made obsolete because it represents a biological process and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a biological process and not a molecular function. To update annotations, use biological_process term 'vesicle-mediated transport ; GO:0016192'." to "This term was made obsolete because it represents a biological process and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a biological process and not a molecular function. To update annotations, consider biological_process terms 'synaptic vesicle to endosome fusion ; GO:0016189', 'vesicle fusion ; GO:0006906' or its children, 'vesicle fusion with nuclear membrane ; GO:0007086', 'vesicle fusion with peroxisome ; GO:0019817', and 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it represents a biological process and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a biological process and not a molecular function. To update annotations, consider biological_process term 'vesicle targeting ; GO:0006903' or its children and external ontology term 'synaptic vesicle targeting ; GO:GO:0016080'." to "This term was made obsolete because it represents a biological process and not a molecular function."
* Changed comment from "This term was made obsolete because the activity described by the definition does not exist. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because the activity described by the definition does not exist."
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider molecular_function term 'metal ion binding ; GO:0046872' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because it represents a composite function. To update annotations, consider molecular_function terms 'cadmium ion binding ; GO:0046870' and 'copper ion binding ; GO:0005507'." to "This term was made obsolete because it represents a composite function."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'sequestering of calcium ion ; GO:0051208' and molecular_function term 'calcium ion binding ; GO:0005509'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider biological_process term 'heterophilic cell adhesion ; GO:0007157' or its children and molecular_function term 'sugar binding ; GO:0005529' or its children." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider biological_process term 'heterophilic cell adhesion ; GO:0007157' or its children and molecular_function term 'galactose binding ; GO:0005534'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider biological_process term 'heterophilic cell adhesion ; GO:0007157' or its children and molecular_function term 'mannose binding ; GO:0005537'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, consider biological_process term 'heterophilic cell adhesion ; GO:0007157' or its children and molecular_function term 'N-acetylgalactosamine binding ; GO:0046871'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it was replaced by more appropriate terms. To update annotations, consider molecular_function terms 'acyl binding ; GO:0000035' and 'acyl-CoA binding ; GO:0000062'." to "This term was made obsolete because it was replaced by more appropriate terms."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'protein ubiquitination ; GO:0016567' or its children and molecular_function term 'protein tag ; GO:0031386'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider biological_process term 'protein polyubiquitination ; GO:0000209'." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'triplet codon-amino acid adaptor activity ; GO:0030533'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'ribosome ; GO:0005840' or its children and molecular_function term 'structural constituent of ribosome ; GO:0003735'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents gene products. To update annotations, consider molecular_function term 'RNA modification guide activity ; GO:0030555' or its children." to "This term was made obsolete because it represents gene products."
* Changed comment from "This term was made obsolete because it represents gene products. To update annotations, consider molecular_function terms 'RNA splicing factor activity, transesterification mechanism ; GO:0031202' or its children and 'snRNA binding ; GO:0017069' or its children." to "This term was made obsolete because it represents gene products."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'template for synthesis of G-rich strand of telomere DNA activity ; GO:0000332'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'membrane attack complex ; GO:0005579'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family. To update annotations, consider cellular_component term 'integrin complex ; GO:0008305'." to "This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family."
* Changed comment from "This term was made obsolete because it is a type of cell rather than a cellular component. To update annotations, consider external ontology term 'ascus ; FAO:0000014'." to "This term was made obsolete because it is a type of cell rather than a cellular component. To update annotations, consider the external ontology term 'ascus ; FAO:0000014'."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use molecular_function term 'Ran GTPase binding ; GO:0008536' and consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component terms 'cytoplasm ; GO:0005737' or its children, 'nuclear pore ; GO:0005643' or its children, and 'nucleus ; GO:0005634' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RFC is not used in current literature. To update annotations, use cellular_component terms 'DNA replication factor C complex ; GO:0005663' and 'PCNA complex ; GO:0043626'." to "This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RFC is not used in current literature."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'transcription factor TFIID complex ; GO:0005669'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions. To update annotations, consider cellular_component terms 'chromosome ; GO:0005694' or its children, 'condensed chromosome ; GO:0000793' or its children, and 'condensed nuclear chromosome ; GO:0000794' or its children." to "This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions."
* Changed comment from "This term was made obsolete because the definition was too sequence oriented and too restrictive. To update annotations, consider cellular_component terms 'chromosome, telomeric region ; GO:0000781' or its children and 'telomere cap complex ; GO:0000782' or its children." to "This term was made obsolete because the definition was too sequence oriented and too restrictive."
* Changed comment from "This term was made obsolete because it is genetically defined region and not a specific subcellular localization. To update annotations, consider cellular_component term 'chromosome, pericentric region ; GO:0000775' or its children." to "This term was made obsolete because it is genetically defined region and not a specific subcellular localization."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'chromosome ; GO:0005694' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a process. To update annotations, consider cellular_component terms 'condensed chromosome ; GO:0000793' or its children and 'condensed nuclear chromosome ; GO:0000794' or its children." to "This term was made obsolete because it is based on a process."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component term 'chromosome ; GO:0005694' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a temporal division of the cell cycle. To update annotations, consider cellular_component terms 'condensed chromosome ; GO:0000793' or its children and 'condensed nuclear chromosome ; GO:0000794' or its children." to "This term was made obsolete because it is based on a temporal division of the cell cycle."
* Changed comment from "This term was made obsolete because it is based on a process. To update annotations, consider cellular_component term 'condensed nuclear chromosome ; GO:0000794' or its children." to "This term was made obsolete because it is based on a process."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, consider cellular_component term 'proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0045263' or its children." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric. To update annotations, consider biological_process term 'protein targeting to peroxisome ; GO:0006625' or its children, cellular_component term 'peroxisomal part ; GO:0044439' or its children, and molecular_function term 'peroxisome targeting sequence binding ; GO:0000268' or its children." to "This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric."
* Changed comment from "This term was made obsolete because its position and synonym implied that it confused a coated vesicle with the coat itself. To update annotations, consider cellular_component terms 'COPI vesicle coat ; GO:0030126' and 'COPI-coated vesicle ; GO:0030137' or its children." to "This term was made obsolete because its position and synonym implied that it confused a coated vesicle with the coat itself."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. To update annotations, consider cellular_component term 'ER to Golgi transport vesicle ; GO:0030134' or its children." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required."
* Changed comment from "This term was made obsolete because it was being used to describe two different components. To update annotations, consider cellular_component terms 'secretory granule ; GO:0030141' or its children and 'transport vesicle ; GO:0030133' or its children." to "This term was made obsolete because it was being used to describe two different components."
* Changed comment from "This term was made obsolete because its parent was made obsolete. To update annotations, consider cellular_component terms 'secretory granule membrane ; GO:0030667' or its children and 'transport vesicle membrane ; GO:0030658' or its children." to "This term was made obsolete because its parent was made obsolete."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. To update annotations, consider cellular_component term 'ER to Golgi transport vesicle ; GO:0030134' or its children." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. To update annotations, consider cellular_component term 'Golgi to ER transport vesicle ; GO:0030142' or its children." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles. To update annotations, consider cellular_component term 'transport vesicle ; GO:0030133' or its children." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. To update annotations, consider cellular_component term 'transport vesicle ; GO:0030133' or its children." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required. To update annotations, use cellular_component term 'endocytic vesicle ; GO:0030139'." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required."
* Changed comment from "This term was made obsolete because its definition was inaccurate. To update annotations, consider cellular_component terms 'proteasome complex (sensu Eukaryota) ; GO:0000502' or its children, 'proteasome core complex (sensu Bacteria) ; GO:0000503', and 'proteasome regulatory particle (sensu Bacteria) ; GO:0000504'." to "This term was made obsolete because its definition was inaccurate."
* Changed comment from "This term was made obsolete because it describes the composition (i.e. proteoglycan) and not the location of a gene product. To update annotations, use cellular_component term 'integral to plasma membrane ; GO:0005887'." to "This term was made obsolete because it describes the composition (i.e. proteoglycan) and not the location of a gene product."
* Changed comment from "This term was made obsolete because it was positioned incorrectly, so the replacement term has a definition different from what this term appeared to mean. To update annotations, use cellular_component term 'AP-type membrane coat adaptor complex ; GO:0030119'." to "This term was made obsolete because it was positioned incorrectly, so the replacement term has a definition different from what this term appeared to mean."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous. To update annotations, consider cellular_component term 'AP-1 adaptor complex ; GO:0030121'." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous."
* Changed comment from "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous. To update annotations, consider cellular_component term 'AP-2 adaptor complex ; GO:0030122'." to "This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous."
* Changed comment from "This term was made obsolete because it represents a type of whole cell rather than a cellular component. To update annotations, consider cellular_component terms 'mating projection ; GO:0005937' or its children and 'mating projection base ; GO:0001400' and external ontology term 'shmoo ; FAO:0001023'." to "This term was made obsolete because it represents a type of whole cell rather than a cellular component. To update annotations, consider the external ontology term 'shmoo ; FAO:0001023'."
* Changed comment from "This term was made obsolete because it is ambiguous (there are several debranching enzymes) and because it probably represents the glycogen debranching enzyme which is a single gene product and not a complex. To update annotations, consider cellular_component term 'isoamylase complex ; GO:0043033' or its children." to "This term was made obsolete because it is ambiguous (there are several debranching enzymes) and because it probably represents the glycogen debranching enzyme which is a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component term 'fibrinogen complex ; GO:0005577'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component term 'fibrinogen complex ; GO:0005577'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component term 'fibrinogen complex ; GO:0005577'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider molecular_function term 'acetate-CoA ligase activity ; GO:0003987'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, use biological_process term 'electron transport ; GO:0006118'." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because the term string represents a molecular function and not a biological pathway. To update annotations, consider biological_process terms 'electron transport ; GO:0006118' or its children and 'glutathione metabolic process ; GO:0006749' or its children and molecular_function term 'glutathione-disulfide reductase activity ; GO:0004362'." to "This term was made obsolete because the term string represents a molecular function and not a biological pathway."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process term 'electron transport ; GO:0006118' or its children and molecular_function term 'protein-disulfide reductase (glutathione) activity ; GO:0019153'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because the term string was ambiguous and the term may represent a molecular function. To update annotations, consider biological_process term 'electron transport ; GO:0006118' or its children and molecular_function term '6-phosphofructokinase activity ; GO:0003872'." to "This term was made obsolete because the term string was ambiguous and the term may represent a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process terms 'dihydrolipoamide metabolic process ; GO:0051068' and 'electron transport ; GO:0006118' or its children and molecular_function term 'dihydrolipoyl dehydrogenase activity ; GO:0004148'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process term 'electron transport ; GO:0006118' or its children and molecular_function term 'dihydrolipoyl dehydrogenase activity ; GO:0004148'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process terms 'dihydrobiopterin metabolic process ; GO:0051066' and 'electron transport ; GO:0006118' or its children and molecular_function term 'pteridine reductase activity ; GO:0047040'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process terms 'dihydropteridine metabolic process ; GO:0051067' and 'electron transport ; GO:0006118' or its children and molecular_function term '6,7-dihydropteridine reductase activity ; GO:0004155'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process terms 'purine base metabolic process ; GO:0006144' or its children, 'purine nucleoside metabolic process ; GO:0042278' or its children, and 'purine nucleotide metabolic process ; GO:0006163' or its children." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'purine nucleosidase activity ; GO:0008477'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'adenosine deaminase activity ; GO:0004000'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'deoxyadenosine deaminase activity ; GO:0046936'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'ribonucleoside-diphosphate reductase activity ; GO:0004748' or its children." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'AMP deaminase activity ; GO:0003876'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'ADP reductase activity ; GO:0051061'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process terms 'pyrimidine base metabolic process ; GO:0006206' or its children, 'pyrimidine nucleoside metabolic process ; GO:0006213' or its children, and 'pyrimidine nucleotide metabolic process ; GO:0006220' or its children." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'uridine kinase activity ; GO:0004849'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'TTP reductase activity ; GO:0051064'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'CDP reductase activity ; GO:0051063'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'CTP reductase activity ; GO:0051065'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider molecular_function term 'UDP reductase activity ; GO:0051062'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because this process can be subdivided into multiple processes. To update annotations, consider biological_process term 'nucleotide-excision repair ; GO:0006289' or its children." to "This term was made obsolete because this process can be subdivided into multiple processes."
* Changed comment from "This term was made obsolete because it is a substrate specific DNA repair process. To update annotations, consider biological_process terms 'nucleotide-excision repair, DNA damage recognition ; GO:0000715' or its children and 'transcription-coupled nucleotide-excision repair, DNA damage recognition ; GO:0000716'." to "This term was made obsolete because it is a substrate specific DNA repair process."
* Changed comment from "This term was made obsolete because 'short patch' is a relative statement, often used ambiguously, and does not necessarily represent a process; the processes it can stand for are base excision repair, nucleotide excision repair, transcription-coupled nucleotide excision repair, and mismatch repair. To update annotations, consider biological_process terms 'base-excision repair ; GO:0006284' or its children and 'nucleotide-excision repair ; GO:0006289' or its children." to "This term was made obsolete because 'short patch' is a relative statement, often used ambiguously, and does not necessarily represent a process; the processes it can stand for are base excision repair, nucleotide excision repair, transcription-coupled nucleotide excision repair, and mismatch repair."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'bent DNA binding ; GO:0003681'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, consider molecular_function term 'random coil DNA binding ; GO:0003695'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'AT DNA binding ; GO:0003680'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'satellite DNA binding ; GO:0003696'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'single-stranded DNA binding ; GO:0003697'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'chromatin insulator sequence binding ; GO:0043035'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents several different processes. To update annotations, consider biological_process terms 'Group I intron splicing ; GO:0000372', 'Group II intron splicing ; GO:0000373', 'Group III intron splicing ; GO:0000374', 'nuclear mRNA splicing, via spliceosome ; GO:0000398' or its children, and 'RNA splicing, via endonucleolytic cleavage and ligation ; GO:0000394' or its children." to "This term was made obsolete because it represents several different processes."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, consider biological_process term 'generation of catalytic spliceosome for second transesterification step ; GO:0000350' or its children and molecular_function term 'second spliceosomal transesterification activity ; GO:0000386' or its children." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, consider biological_process terms 'spliceosomal conformational changes to generate catalytic conformation ; GO:0000393' or its children and 'spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) ; GO:0000388' or its children and molecular_function term 'second spliceosomal transesterification activity ; GO:0000386' or its children." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a process unique to splicing of the MATa1 (A1) pre-mRNA, but a recycling defect exacerbated by the presence of two introns within the same gene. To update annotations, consider biological_process term 'assembly of spliceosomal tri-snRNP ; GO:0000244' or its children." to "This term was made obsolete because it does not represent a process unique to splicing of the MATa1 (A1) pre-mRNA, but a recycling defect exacerbated by the presence of two introns within the same gene."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, consider molecular_function term 'poly(A) binding ; GO:0008143'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it does not represent a process unique to splicing of the tyrosyl (Y) tRNA. To update annotations, consider biological_process term 'tRNA splicing ; GO:0006388'." to "This term was made obsolete because it does not represent a process unique to splicing of the tyrosyl (Y) tRNA."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'aminoacyl-tRNA hydrolase activity ; GO:0004045'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider molecular_function term 'RNA cap binding ; GO:0000339' or its children." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider cellular_component term 'endoplasmic reticulum ; GO:0005783' or its children and molecular_function term 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, consider molecular_function term 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755' or its children." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because the string was ambiguous and the original meaning of the term was hence unknown. To update annotations, consider biological_process terms 'chaperone-mediated protein complex assembly ; GO:0051131' and 'protein folding ; GO:0006457' or its children." to "This term was made obsolete because the string was ambiguous and the original meaning of the term was hence unknown."
* Changed comment from "This term was made obsolete because it presents a molecular function. To update annotations, use molecular_function term 'protein disulfide isomerase activity ; GO:0003756'." to "This term was made obsolete because it presents a molecular function."
* Changed comment from "This term was made obsolete because it is a redundant grouping term. To update annotations, consider biological_process terms 'peptidyl-asparagine hydroxylation ; GO:0042265' or its children and 'peptidyl-aspartic acid hydroxylation ; GO:0042264' or its children." to "This term was made obsolete because it is a redundant grouping term."
* Changed comment from "This term was made obsolete because it represents a single activity. To update annotations, consider molecular_function term 'protein disulfide isomerase activity ; GO:0003756'." to "This term was made obsolete because it represents a single activity."
* Changed comment from "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein. To update annotations, use biological_process term 'protein amino acid prenylation ; GO:0018346'." to "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein."
* Changed comment from "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein. To update annotations, use biological_process term 'protein amino acid farnesylation ; GO:0018347'." to "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein."
* Changed comment from "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein. To update annotations, use biological_process term 'protein amino acid geranylgeranylation ; GO:0018348'." to "This term was made obsolete because the process is not exclusive to the carboxy terminus of a protein."
* Changed comment from "This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation. To update annotations, consider biological_process term 'protein targeting to mitochondrion ; GO:0006626' or its children." to "This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, consider molecular_function term 'lipid binding ; GO:0008289' or its children." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC 1.14.99.22) and so is a function rather than a process. To update annotations, use molecular_function term 'ecdysone 20-monooxygenase activity ; GO:0004501'." to "This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC 1.14.99.22) and so is a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, consider molecular_function term 'juvenile hormone binding ; GO:0005500'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'coenzyme metabolic process ; GO:0006732' or its children and 'prosthetic group metabolic process ; GO:0051189' or its children." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process term 'dihydrofolate metabolic process ; GO:0046452' or its children and molecular_function term 'dihydrofolate reductase activity ; GO:0004146'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, consider biological_process term 'cobalamin metabolic process ; GO:0009235' or its children and molecular_function term 'cob(II)alamin reductase activity ; GO:0050453'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, consider molecular_function term 'catalase activity ; GO:0004096'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'glutathione transferase activity ; GO:0004364'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'peroxidase activity ; GO:0004601'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to insecticide ; GO:0017085'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it is a composite term that represents two individual processes. To update annotations, consider biological_process terms 'potassium ion transport ; GO:0006813' or its children and 'sodium ion transport ; GO:0006814' or its children." to "This term was made obsolete because it is a composite term that represents two individual processes."
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider biological_process term 'metal ion transport ; GO:0030001' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider biological_process term 'transport ; GO:0006810' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it is a composite term that represents two individual processes. To update annotations, consider biological_process terms 'allantoate transport ; GO:0015719' and 'allantoin transport ; GO:0015720'." to "This term was made obsolete because it is a composite term that represents two individual processes."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, use biological_process terms 'alpha-ketoglutarate transport ; GO:0015742', 'malate transport ; GO:0015743', and 'mitochondrial transport ; GO:0006839' and molecular_function term 'oxoglutarate:malate antiporter activity ; GO:0015367'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, use biological_process terms 'aspartate transport ; GO:0015810', 'glutamate transport ; GO:0015813', and 'mitochondrial transport ; GO:0006839'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents function rather than a process. To update annotations, use biological_process terms 'calcium ion transport ; GO:0006816', 'mitochondrial transport ; GO:0006839', and 'sodium ion transport ; GO:0006814' and consider molecular_function term 'calcium:sodium antiporter activity ; GO:0005432'." to "This term was made obsolete because it represents function rather than a process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'ATP:ADP antiporter activity ; GO:0005471'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). To update annotations, consider biological_process term 'cellular calcium ion homeostasis ; GO:0006874' or its children and cellular_component term 'endoplasmic reticulum ; GO:0005783' or its children." to "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport')."
* Changed comment from "This term was made obsolete because the meaning of the term is ambiguous. To update annotations, consider biological_process term 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because the meaning of the term is ambiguous."
* Changed comment from "This term was made obsolete because of the ambiguity in its meaning. To update annotations, consider biological_process terms 'phagocytosis, engulfment ; GO:0006911' or its children and 'phagolysosome formation ; GO:0001845'." to "This term was made obsolete because of the ambiguity in its meaning."
* Changed comment from "This term was made obsolete because more accurate terms were created. To update annotations, consider biological_process term 'induction of apoptosis ; GO:0006917' or its children." to "This term was made obsolete because more accurate terms were created."
* Changed comment from "This term was made obsolete because more accurate terms were created. To update annotations, consider biological_process term 'induction of apoptosis ; GO:0006917' or its children." to "This term was made obsolete because more accurate terms were created."
* Changed comment from "This term was made obsolete because its meaning is vague, and it does not fit with other terms in GO. To update annotations, consider biological_process terms 'response to mechanical stimulus ; GO:0009612' or its children and 'sensory perception of mechanical stimulus ; GO:0050954' or its children." to "This term was made obsolete because its meaning is vague, and it does not fit with other terms in GO."
* Changed comment from "This term was made obsolete because it is redundant outside the context of Saccharomyces biology. To update annotations, consider biological_process term 'karyogamy ; GO:0000741' or its children." to "This term was made obsolete because it is redundant outside the context of Saccharomyces biology."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider biological_process term 'UFP-specific transcription factor mRNA processing during unfolded protein response ; GO:0030969' and molecular_function term 'endoribonuclease activity ; GO:0004521' or its children." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider biological_process term 'UFP-specific transcription factor mRNA processing during unfolded protein response ; GO:0030969' and molecular_function term 'RNA ligase activity ; GO:0008452' or its children." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'centromeric DNA binding ; GO:0019237'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'telomeric DNA binding ; GO:0042162'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because cytoskeleton is neither a process nor a trait, so the term made no sense. To update annotations, consider biological_process term 'cytoskeleton organization and biogenesis ; GO:0007010' or its children." to "This term was made obsolete because cytoskeleton is neither a process nor a trait, so the term made no sense."
* Changed comment from "This term was made obsolete because the term name is ambiguous and appears to encompass two processes. To update annotations, consider biological_process terms 'mitotic sister chromatid cohesion ; GO:0007064' and 'mitotic sister chromatid segregation ; GO:0000070' or its children." to "This term was made obsolete because the term name is ambiguous and appears to encompass two processes."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, consider molecular_function term 'chromatin binding ; GO:0003682' or its children." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents two concepts. To update annotations, consider biological_process terms 'cellular bud site selection ; GO:0000282' or its children and 'establishment of cell polarity ; GO:0030010' or its children and external ontology term 'establishment of cell polarity (sensu Fungi) ; GO:0030468'." to "This term was made obsolete because it represents two concepts."
* Changed comment from "This term was made obsolete because it is a phenotype rather than a biological process. To update annotations, consider biological_process term 'chitin localization ; GO:0006033'." to "This term was made obsolete because it is a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it is a phenotype rather than a biological process. To update annotations, consider biological_process term 'cellular bud site selection ; GO:0000282' or its children." to "This term was made obsolete because it is a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it has been split into two new terms. To update annotations, consider biological_process terms 'entry into host ; GO:0044409' or its children, 'growth or development of symbiont within host ; GO:0044412' or its children, and 'invasive growth (sensu Saccharomyces) ; GO:0001403'." to "This term was made obsolete because it has been split into two new terms."
* Changed comment from "This term was made obsolete because the original meaning of the term is unclear, the current definition is incorrect, and it does not describe a biological process. To update annotations, consider biological_process term 'growth ; GO:0040007' or its children." to "This term was made obsolete because the original meaning of the term is unclear, the current definition is incorrect, and it does not describe a biological process."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, consider molecular_function term 'receptor tyrosine kinase binding ; GO:0030971'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it represents a function. To update annotations, consider molecular_function terms 'transforming growth factor beta binding ; GO:0050431', 'transforming growth factor beta receptor activity, type II ; GO:0005026' or its children, and 'transforming growth factor beta receptor binding ; GO:0005160' or its children." to "This term was made obsolete because it represents a function."
* Changed comment from "This term was made obsolete because hydrolysis is a reaction, not a process. To update annotations, consider molecular_function term 'phosphoinositide phospholipase C activity ; GO:0004435'." to "This term was made obsolete because hydrolysis is a reaction, not a process."
* Changed comment from "This term was made obsolete because it does not make sense. To update annotations, consider biological_process term 'calcium-mediated signaling ; GO:0019722' or its children." to "This term was made obsolete because it does not make sense."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, consider biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because its meaning was unclear. To update annotations, consider biological_process term 'I-kappaB kinase/NF-kappaB cascade ; GO:0007249' or its children." to "This term was made obsolete because its meaning was unclear."
* Changed comment from "This term was made obsolete because the term string made no sense. To update annotations, consider biological_process term 'synaptic transmission ; GO:0007268' or its children." to "This term was made obsolete because the term string made no sense."
* Changed comment from "This term was made obsolete because more appropriate terms were created. Morphogenesis in plants also occurs outside of embryogenesis. To update annotations, consider biological_process terms 'anatomical structure morphogenesis ; GO:0009653' or its children and 'embryonic development ; GO:0009790' or its children." to "This term was made obsolete because more appropriate terms were created. Morphogenesis in plants also occurs outside of embryogenesis."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process term 'embryonic pattern specification ; GO:0009880' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process terms 'organ morphogenesis ; GO:0009887' or its children and 'tissue development ; GO:0009888' or its children." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because its meaning is ambiguous. To update annotations, consider biological_process terms 'nervous system development ; GO:0007399' or its children and 'neurological system process ; GO:0050877' or its children." to "This term was made obsolete because its meaning is ambiguous."
* Changed comment from "This term was made obsolete because it does not stipulate which anatomical part is involved in the process. To update annotations, consider biological_process term 'prothoracic disc morphogenesis ; GO:0007470'." to "This term was made obsolete because it does not stipulate which anatomical part is involved in the process."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process terms 'lymph gland development ; GO:0048542' or its children and 'lymph node development ; GO:0048535'." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms. To update annotations, consider biological_process term 'dosage compensation ; GO:0007549' or its children." to "This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms."
* Changed comment from "This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms. To update annotations, consider biological_process term 'dosage compensation ; GO:0007549' or its children." to "This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process term 'progressive alteration of chromatin during cell aging ; GO:0001301' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process term 'age-dependent general metabolic decline ; GO:0007571' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process term 'age-dependent general metabolic decline ; GO:0007571' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'. To update annotations, use biological_process term 'cell aging ; GO:0007569'." to "This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process terms 'age-dependent general metabolic decline ; GO:0007571' or its children and 'nucleolar fragmentation ; GO:0007576' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because a more correct term has been created. To update annotations, consider biological_process term 'autophagic cell death ; GO:0048102' or its children." to "This term was made obsolete because a more correct term has been created."
* Changed comment from "This term was made obsolete because it reflected a trait or phenotype. To update annotations, consider biological_process term 'chromatin silencing at silent mating-type cassette ; GO:0030466'." to "This term was made obsolete because it reflected a trait or phenotype."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process term 'age-dependent general metabolic decline ; GO:0007571' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because it is ambiguous; 'killer activity' could refer to several different processes. To update annotations, consider biological_process term 'natural killer cell mediated cytotoxicity ; GO:0042267' or its children." to "This term was made obsolete because it is ambiguous; 'killer activity' could refer to several different processes."
* Copied GO:0007588 to GO:0046903 with type OBO_REL:is_a
* Deleted GO:0007589 --OBO_REL:is_a--> GO:0007588
* Changed comment from "This term was made obsolete because it represents metabolism within the fat body not of the fat body. To update annotations, consider biological_process terms 'metabolic process ; GO:0008152' or its children and 'storage protein import into fat body ; GO:0015032'." to "This term was made obsolete because it represents metabolism within the fat body not of the fat body."
* Changed comment from "This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage. To update annotations, consider biological_process terms 'detection of chemical stimulus during sensory perception of taste ; GO:0050912' or its children and 'sensory perception of taste ; GO:0050909' or its children." to "This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, use biological_process term 'larval behavior ; GO:0030537'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because it does not describe an activity. To update annotations, use cellular_component term 'fibrinogen complex ; GO:0005577'." to "This term was made obsolete because it does not describe an activity."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'membrane attack complex ; GO:0005579'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use biological_process term 'calcium-dependent cell-cell adhesion ; GO:0016339', cellular_component term 'integral to membrane ; GO:0016021', and molecular_function term 'protein binding ; GO:0005515'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because the function is covered by a parent term. To update annotations, use molecular_function term 'structural constituent of chorion ; GO:0005213'." to "This term was made obsolete because the function is covered by a parent term."
* Changed comment from "This term was made obsolete because its name is ambiguous, and it was never defined. To update annotations, consider molecular_function terms 'pattern recognition receptor activity ; GO:0008329' or its children and 'scavenger receptor activity ; GO:0005044'." to "This term was made obsolete because its name is ambiguous, and it was never defined."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider biological_process terms 'regulation of acyl-CoA biosynthetic process ; GO:0050812', 'regulation of insulin secretion ; GO:0050796' or its children, and 'regulation of steroid biosynthetic process ; GO:0050810' or its children and molecular_function terms 'benzodiazepine receptor binding ; GO:0030156', 'diazepam binding ; GO:0050809', 'enzyme inhibitor activity ; GO:0004857' or its children, and 'GABA receptor binding ; GO:0050811'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it describes a cellular location rather than a function. To update annotations, use molecular_function term 'nutrient reservoir activity ; GO:0045735'." to "This term was made obsolete because it describes a cellular location rather than a function."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, use biological_process term 'adult behavior ; GO:0030534'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because there is no evidence that this enzyme ever exists as anything other than a monomer. To update annotations, consider molecular_function term 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310'." to "This term was made obsolete because there is no evidence that this enzyme ever exists as anything other than a monomer."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider molecular_function terms 'guanylate cyclase activity ; GO:0004383' and 'receptor activity ; GO:0004872' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a specific gene product rather than a molecular function. To update annotations, consider molecular_function term 'protein binding, bridging ; GO:0030674' or its children." to "This term was made obsolete because it represents a specific gene product rather than a molecular function."
* Changed comment from "This term was made obsolete because the term name is ambiguous. To update annotations, consider biological_process term 'phototransduction ; GO:0007602' or its children." to "This term was made obsolete because the term name is ambiguous."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function term 'lipid transporter activity ; GO:0005319'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, use biological_process term 'puparial adhesion ; GO:0007594' and molecular_function term 'structural molecule activity ; GO:0005198'." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered. To update annotations, consider molecular_function terms '4-amino-4-deoxychorismate lyase activity ; GO:0008696' and '4-amino-4-deoxychorismate synthase activity ; GO:0046820'." to "This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term. To update annotations, use biological_process term 'larval behavior ; GO:0030537'." to "This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to carbamate ; GO:0046681'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to cyclodiene ; GO:0046682'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to DDT ; GO:0046680'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to organophosphorus ; GO:0046683'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to pyrethroid ; GO:0046684'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it covers multiple processes and is now covered by more specific terms. To update annotations, consider biological_process term 'viral genome replication ; GO:0019079' or its children." to "This term was made obsolete because it covers multiple processes and is now covered by more specific terms."
* Removed comment
* Changed comment from "This term was made obsolete because it does not represent a true biological function, rather a pathology that occurs when a particular gene product is inactivated in some way. To update annotations, consider biological_process term 'regulation of progression through cell cycle ; GO:0000074' or its children." to "This term was made obsolete because it does not represent a true biological function, rather a pathology that occurs when a particular gene product is inactivated in some way."
* Changed comment from "This term was made obsolete because it represents involvement in a biological process. To update annotations, use biological_process term 'anti-apoptosis ; GO:0006916'." to "This term was made obsolete because it represents involvement in a biological process."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function terms 'nutrient reservoir activity ; GO:0045735' and 'structural molecule activity ; GO:0005198' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because the term has been used in the literature by groups in different areas of biology with a number of varying explicit and implicit definitions, and more appropriate terms were created. To update annotations, consider biological_process terms 'cell death ; GO:0008219' or its children, 'cell killing ; GO:0001906' or its children, 'cytolysis ; GO:0019835' or its children, and 'programmed cell death ; GO:0012501' or its children." to "This term was made obsolete because the term has been used in the literature by groups in different areas of biology with a number of varying explicit and implicit definitions, and more appropriate terms were created."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'defense response to Gram-positive bacterium ; GO:0050830' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it describes involvement in a process and not a function. To update annotations, consider biological_process term 'defense response to Gram-negative bacterium ; GO:0050829' or its children." to "This term was made obsolete because it describes involvement in a process and not a function."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider molecular_function term 'antigen binding ; GO:0003823' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, consider cellular_component term 'lysosomal proton-transporting V-type ATPase complex ; GO:0046611' or its children." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, consider biological_process term 'RNA splicing ; GO:0008380' or its children and molecular_function term 'RNA splicing factor activity, transesterification mechanism ; GO:0031202' or its children." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it represents a function. To update annotations, consider molecular_function terms 'transforming growth factor beta binding ; GO:0050431', 'transforming growth factor beta receptor activity, type I ; GO:0005025' or its children, and 'transforming growth factor beta receptor binding ; GO:0005160' or its children." to "This term was made obsolete because it represents a function."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, use cellular_component term 'eukaryotic translation initiation factor 4F complex ; GO:0016281'." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because it describes a class of gene products. To update annotations, consider biological_process term 'cell adhesion ; GO:0007155' or its children, cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms 'carbohydrate binding ; GO:0030246' or its children, 'cell adhesion molecule binding ; GO:0050839' or its children, and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it describes a class of gene products."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, consider biological_process term 'behavioral response to cocaine ; GO:0048148'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term. To update annotations, use biological_process term 'larval feeding behavior ; GO:0030536'." to "This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term."
* Changed comment from "This term was made obsolete because it includes cellular component information. To update annotations, consider cellular_component term 'kinetochore ; GO:0000776' or its children and molecular_function term 'microtubule motor activity ; GO:0003777' or its children." to "This term was made obsolete because it includes cellular component information."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, use biological_process term 'microtubule severing ; GO:0051013' and molecular_function term 'microtubule binding ; GO:0008017'." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'negative regulation of coagulation ; GO:0050819'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it describes a cellular component rather than a molecular function. To update annotations, use cellular_component term 'heterogeneous nuclear ribonucleoprotein complex ; GO:0030530'." to "This term was made obsolete because it describes a cellular component rather than a molecular function."
* Changed comment from "This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref. To update annotations, consider molecular_function term '1-phosphatidylinositol-5-phosphate 4-kinase activity ; GO:0016309'." to "This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref."
* Changed comment from "This term was made obsolete because it describes a gene product. To update annotations, consider biological_process term 'cAMP metabolic process ; GO:0046058' or its children and molecular_function terms 'adenylate cyclase activity ; GO:0004016' or its children and 'hormone activity ; GO:0005179' or its children." to "This term was made obsolete because it describes a gene product."
* Changed comment from "This term was made obsolete because it represents a biological process and not a molecular function. To update annotations, use biological_process term 'phospholipid scrambling ; GO:0017121'." to "This term was made obsolete because it represents a biological process and not a molecular function."
* Changed comment from "This term was made obsolete because it is a conglomeration of three terms. To update annotations, consider molecular_function terms 'glutamate binding ; GO:0016595', 'glycine binding ; GO:0016594', and 'thienylcyclohexylpiperidine binding ; GO:0016596'." to "This term was made obsolete because it is a conglomeration of three terms."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'intracellular ; GO:0005622' or its children and molecular_function term 'peptide receptor activity ; GO:0001653' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'extracellular region ; GO:0005576' or its children and molecular_function term 'peptide receptor activity ; GO:0001653' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, consider molecular_function terms 'chromatin binding ; GO:0003682' or its children, 'DNA binding ; GO:0003677' or its children, 'microtubule binding ; GO:0008017' or its children, and 'protein binding, bridging ; GO:0030674' or its children." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use biological_process term 'translation ; GO:0006412' and molecular_function term 'GTPase activity ; GO:0003924' and consider molecular_function terms 'translation factor activity, nucleic acid binding ; GO:0008135' or its children and 'translation factor activity, nucleic acid binding ; GO:0008135' or its children and molecular_function terms 'translation factor activity, nucleic acid binding ; GO:0008135' or its children and 'translation factor activity, nucleic acid binding ; GO:0008135' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use cellular_component term 'signal recognition particle, endoplasmic reticulum targeting ; GO:0005786' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process term 'endocytosis ; GO:0006897' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use biological_process term 'tubulin folding ; GO:0007021' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents more than one molecular function. To update annotations, consider molecular_function terms 'ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism ; GO:0015662' or its children, 'cadmium ion transmembrane transporter activity ; GO:0015086' or its children, 'cobalt ion transmembrane transporter activity ; GO:0015087' or its children, 'lead ion transmembrane transporter activity ; GO:0015094', 'nickel ion transmembrane transporter activity ; GO:0015099' or its children, and 'zinc ion transmembrane transporter activity ; GO:0005385' or its children." to "This term was made obsolete because it represents more than one molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. To update annotations, consider biological_process term 'microtubule-based movement ; GO:0007018' or its children and molecular_function term 'microtubule motor activity ; GO:0003777' or its children." to "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information."
* Changed comment from "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. To update annotations, use molecular_function term 'microfilament motor activity ; GO:0000146' and consider biological_process term 'actin filament-based movement ; GO:0030048' or its children." to "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function term 'ATPase activity, coupled ; GO:0042623' and consider biological_process term 'protein folding ; GO:0006457' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information. To update annotations, use molecular_function term 'ATPase activity, coupled ; GO:0042623' and consider biological_process term 'chromatin assembly or disassembly ; GO:0006333' or its children." to "This term was made obsolete because it represents a class of gene products, and its definition incorporates process information."
* Changed comment from "This term was made obsolete because it incorporates process information. To update annotations, use molecular_function term 'ATPase activity, coupled ; GO:0042623' and consider biological_process term 'peroxisome organization and biogenesis ; GO:0007031' or its children." to "This term was made obsolete because it incorporates process information."
* Changed comment from "This term was made obsolete because it mentions a component term in the term text string. To update annotations, consider molecular_function term 'ATPase activity ; GO:0016887' or its children." to "This term was made obsolete because it mentions a component term in the term text string."
* Changed comment from "This term was made obsolete because it incorporates process information. To update annotations, use molecular_function term 'ATPase activity, coupled ; GO:0042623' and consider biological_process terms 'membrane fusion ; GO:0006944' or its children and 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it incorporates process information."
* Changed comment from "This term was made obsolete because 'cytoskeleton' is not an activity, and regulation of its distribution or modification belongs in the process ontology. To update annotations, consider biological_process term 'cytoskeleton organization and biogenesis ; GO:0007010' or its children." to "This term was made obsolete because 'cytoskeleton' is not an activity, and regulation of its distribution or modification belongs in the process ontology."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'GTPase activity ; GO:0003924' and consider biological_process terms 'regulation of cell growth ; GO:0001558' or its children and 'regulation of progression through cell cycle ; GO:0000074' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a biological process and a molecular function. To update annotations, consider biological_process term 'protein modification process ; GO:0006464' or its children and molecular_function terms 'protein binding ; GO:0005515' or its children and 'protein tag ; GO:0031386'." to "This term was made obsolete because it represents a biological process and a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process terms 'positive regulation of saliva secretion ; GO:0046878', 'positive regulation of smooth muscle contraction ; GO:0045987', and 'positive regulation of vasodilation ; GO:0045909' and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'actin filament polymerization ; GO:0030041' and molecular_function term 'identical protein binding ; GO:0042802'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'DNA topoisomerase (ATP-hydrolyzing) activity ; GO:0003918'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it is a redundant grouping term with only one child. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on NADH or NADPH ; GO:0016651' or its children." to "This term was made obsolete because it is a redundant grouping term with only one child."
* Changed comment from "This term was made obsolete because it represents a bifunctional gene product. To update annotations, use molecular_function terms 'carnitine-CoA ligase activity ; GO:0051108' and 'crotonobetaine-CoA ligase activity ; GO:0051109'." to "This term was made obsolete because it represents a bifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function terms 'damaged DNA binding ; GO:0003684' or its children, 'DNA N-glycosylase activity ; GO:0019104' or its children, 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' or its children, 'endonuclease activity ; GO:0004519' or its children, 'oxidized pyrimidine base lesion DNA N-glycosylase activity ; GO:0000703', and 'phosphoric diester hydrolase activity ; GO:0008081' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a process rather than a function. To update annotations, use biological_process term 'enterobactin biosynthetic process ; GO:0009239'." to "This term was made obsolete because it represents a process rather than a function."
* Changed comment from "This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered. To update annotations, consider molecular_function terms '4-amino-4-deoxychorismate lyase activity ; GO:0008696' and '4-amino-4-deoxychorismate synthase activity ; GO:0046820'." to "This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered."
* Changed comment from "This term was made obsolete because it represents three different molecular functions. To update annotations, consider biological_process term 'siroheme biosynthetic process ; GO:0019354' and molecular_function terms 'precorrin-2 dehydrogenase activity ; GO:0043115', 'sirohydrochlorin ferrochelatase activity ; GO:0051266', and 'uroporphyrin-III C-methyltransferase activity ; GO:0004851'." to "This term was made obsolete because it represents three different molecular functions."
* Removed comment
* Changed comment from "This term was made obsolete because it was defined inaccurately. To update annotations, consider cellular_component term '1-2nm peptidoglycan-based cell wall ; GO:0009276'." to "This term was made obsolete because it was defined inaccurately."
* Changed comment from "This term was made obsolete because it was defined inaccurately. To update annotations, consider cellular_component term '1-2nm peptidoglycan-based cell wall ; GO:0009276'." to "This term was made obsolete because it was defined inaccurately."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to drug ; GO:0042493'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because the catalytic activity resides in a single polypeptide rather than a complex, and the complex is represented by a different GO term. To update annotations, consider cellular_component term 'fatty acid synthase complex ; GO:0005835' or its children." to "This term was made obsolete because the catalytic activity resides in a single polypeptide rather than a complex, and the complex is represented by a different GO term."
* Changed comment from "This term was made obsolete because the activity dihydrolipoamide dehydrogenase is held by a single protein (Lpd1 in yeast), which is one of the components of three different complexes: 2-oxoglutarate dehydrogenase, pyruvate dehydrogenase, and branch chain amino acid dehydrogenase, so dihydrolipoamide dehydrogenase is not a complex itself. To update annotations, consider cellular_component terms 'alpha-ketoglutarate dehydrogenase complex ; GO:0045240' or its children and 'pyruvate dehydrogenase complex ; GO:0045254' or its children and molecular_function term 'dihydrolipoyl dehydrogenase activity ; GO:0004148'." to "This term was made obsolete because the activity dihydrolipoamide dehydrogenase is held by a single protein (Lpd1 in yeast), which is one of the components of three different complexes: 2-oxoglutarate dehydrogenase, pyruvate dehydrogenase, and branch chain amino acid dehydrogenase, so dihydrolipoamide dehydrogenase is not a complex itself."
* Changed comment from "This term was made obsolete because dihydrolipoamide S-succinyltransferase itself is not a complex, it is a component of the 2-oxoglutarate dehydrogenase complex, the activity dihydrolipoamide S-succinyltransferase is contained in a single polypeptide. To update annotations, consider cellular_component term 'oxoglutarate dehydrogenase complex ; GO:0045252' or its children." to "This term was made obsolete because dihydrolipoamide S-succinyltransferase itself is not a complex, it is a component of the 2-oxoglutarate dehydrogenase complex, the activity dihydrolipoamide S-succinyltransferase is contained in a single polypeptide."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to toxin ; GO:0009636'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a phenotype rather than a biological process. To update annotations, consider biological_process terms 'pathogenesis ; GO:0009405' and 'viral reproduction ; GO:0016032' or its children." to "This term was made obsolete because it represents a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider biological_process term 'response to metal ion ; GO:0010038' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use cellular_component term 'fimbrium ; GO:0009289'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function terms 'electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity ; GO:0045155', 'electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153', 'electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity ; GO:0045158', 'electron transporter, transferring electrons within cytochrome c oxidase complex activity ; GO:0045154', 'electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity ; GO:0045156', and 'electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity ; GO:0045157'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within cytochrome c oxidase complex activity ; GO:0045154'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity ; GO:0045155'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity ; GO:0045158'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity ; GO:0045153'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity ; GO:0045158'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it describes a class of gene products rather than a molecular function. To update annotations, use molecular_function term 'cytochrome-c oxidase activity ; GO:0004129'." to "This term was made obsolete because it describes a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a class of gene products rather than a molecular function. To update annotations, use molecular_function term 'cytochrome-c oxidase activity ; GO:0004129'." to "This term was made obsolete because it describes a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a class of gene products rather than a molecular function. To update annotations, use molecular_function term 'cytochrome-c oxidase activity ; GO:0004129'." to "This term was made obsolete because it describes a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a class of gene products rather than a molecular function. To update annotations, use molecular_function term 'cytochrome-c oxidase activity ; GO:0004129'." to "This term was made obsolete because it describes a class of gene products rather than a molecular function."
* Changed comment from "This term was made obsolete because it represent a gene product. To update annotations, consider molecular_function terms 'glutathione disulfide oxidoreductase activity ; GO:0015038' or its children and 'thiol-disulfide exchange intermediate activity ; GO:0030508'." to "This term was made obsolete because it represent a gene product."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because more specific children exist. To update annotations, consider cellular_component terms 'chromatophore ; GO:0042716' or its children and 'plasma membrane-derived thylakoid ; GO:0030075' or its children." to "This term was made obsolete because more specific children exist."
* Removed comment
* Changed comment from "This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage. To update annotations, consider biological_process term 'sensory perception of mechanical stimulus ; GO:0050954' or its children." to "This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to other organism ; GO:0051707'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to bacterium ; GO:0009617'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to fungus ; GO:0009620'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process. To update annotations, consider biological_process term 'response to cold ; GO:0009409' or its children." to "This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process. To update annotations, consider biological_process terms 'drought recovery ; GO:0009819' and 'response to water deprivation ; GO:0009414' or its children." to "This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, consider biological_process term 'response to metal ion ; GO:0010038' or its children." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use molecular_function term 'oxygen evolving activity ; GO:0010242'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, use cellular_component term 'SCF ubiquitin ligase complex ; GO:0019005'." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because its meaning was changed significantly. To update annotations, consider biological_process term 'cytokinesis by cell plate formation ; GO:0000911' or its children." to "This term was made obsolete because its meaning was changed significantly."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use biological_process term 'cell growth ; GO:0016049' and cellular_component term 'cellulose and pectin-containing cell wall ; GO:0009505'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it does not refer to a specific reaction but rather to a process which results in the formation of AMP. To update annotations, consider biological_process term 'AMP metabolic process ; GO:0046033' or its children." to "This term was made obsolete because it does not refer to a specific reaction but rather to a process which results in the formation of AMP."
* Deleted GO:0009996 --OBO_REL:is_a--> GO:0045596
* Copied GO:0009996 to GO:0010454 with type OBO_REL:is_a
* Changed comment from "This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology. To update annotations, use biological_process terms 'adenine salvage ; GO:0006168', 'adenosine salvage ; GO:0006169', 'hypoxanthine salvage ; GO:0043103', and 'inosine salvage ; GO:0006190'." to "This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology."
* Changed comment from "This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology. To update annotations, use biological_process terms 'guanine salvage ; GO:0006178', 'guanosine salvage ; GO:0006179', 'hypoxanthine salvage ; GO:0043103', and 'inosine salvage ; GO:0006190'." to "This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology."
* Changed comment from "This term was made obsolete because it did not represent a concept discrete from its sibling terms. To update annotations, consider biological_process terms 'bipolar cell growth ; GO:0042815' or its children and 'monopolar cell growth ; GO:0042814' or its children." to "This term was made obsolete because it did not represent a concept discrete from its sibling terms."
* Changed comment from "This term was made obsolete because it was incorrectly defined. To update annotations, consider biological_process term 'sporocyte differentiation ; GO:0048533'." to "This term was made obsolete because it was incorrectly defined."
* Changed comment from "This term was made obsolete because it implies further processing of an end product rather than its production. To update annotations, use biological_process term 'miRNA-mediated gene silencing, production of miRNAs ; GO:0035196'." to "This term was made obsolete because it implies further processing of an end product rather than its production."
* Changed comment from "This term was made obsolete because it represents a process that is not known to occur. To update annotations, use biological_process term 'miRNA-mediated gene silencing, production of miRNAs ; GO:0035196'." to "This term was made obsolete because it represents a process that is not known to occur."
* Changed comment from "This term was made obsolete because it does not represent a function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a function."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use molecular_function term 'electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity ; GO:0046028'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it contains both process and function information. To update annotations, consider biological_process term 'photosynthetic electron transport ; GO:0009767' or its children and molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it contains both process and function information."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'extrinsic to membrane ; GO:0019898' or its children and molecular_function term 'receptor activity ; GO:0004872' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it is a grouping term representing a set of gene products. To update annotations, consider molecular_function term 'oxygen binding ; GO:0019825' or its children." to "This term was made obsolete because it is a grouping term representing a set of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process term 'phototransduction ; GO:0007602' or its children, cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process terms 'phototransduction, visible light ; GO:0007603' and 'UV-A, blue light phototransduction ; GO:0009588', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process term 'phototransduction, visible light ; GO:0007603', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process terms 'phototransduction, visible light ; GO:0007603' and 'red, far-red light phototransduction ; GO:0009585', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process terms 'phototransduction, visible light ; GO:0007603' and 'UV-A, blue light phototransduction ; GO:0009588', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process term 'phototransduction, visible light ; GO:0007603', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process term 'phototransduction, UV ; GO:0007604', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it represents a classification of molecules and not a molecular function. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405' and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a classification of molecules and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function terms '1-phosphatidylinositol-3-kinase activity ; GO:0016303', 'phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934', and 'phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it refers to a class of gene products. To update annotations, use molecular_function term '1-phosphatidylinositol-3-kinase regulator activity ; GO:0046935'." to "This term was made obsolete because it refers to a class of gene products."
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider molecular_function term 'metal ion transmembrane transporter activity ; GO:0046873' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children and molecular_function term 'protein transporter activity ; GO:0008565' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider molecular_function terms 'cofactor transporter activity ; GO:0051184' or its children and 'vitamin transporter activity ; GO:0051183' or its children." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it represents two molecular functions. To update annotations, consider molecular_function terms 'polyol transmembrane transporter activity ; GO:0015166' or its children and 'sugar transmembrane transporter activity ; GO:0051119' or its children." to "This term was made obsolete because it represents two molecular functions."
* Changed comment from "This term was made obsolete because it represents three molecular functions. To update annotations, consider molecular_function terms 'amide transporter activity ; GO:0042887' or its children, 'amine transmembrane transporter activity ; GO:0005275' or its children, and 'polyamine transmembrane transporter activity ; GO:0015203' or its children." to "This term was made obsolete because it represents three molecular functions."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process terms 'pathogenesis ; GO:0009405' and 'pore complex biogenesis ; GO:0046931', cellular_component term 'pore complex ; GO:0046930' or its children, and molecular_function terms 'structural molecule activity ; GO:0005198' or its children and 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents two molecular functions. To update annotations, consider molecular_function terms 'galactose uniporter activity ; GO:0050782' and 'glucose uniporter activity ; GO:0015304'." to "This term was made obsolete because it represents two molecular functions."
* Changed comment from "This term was made obsolete because it represents two molecular functions. To update annotations, consider molecular_function terms 'galactose:hydrogen symporter activity ; GO:0015517' and 'lactose:hydrogen symporter activity ; GO:0015528'." to "This term was made obsolete because it represents two molecular functions."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'nitrate transmembrane transporter activity ; GO:0015112' or its children, 'nitrite transmembrane transporter activity ; GO:0015113' or its children, and 'secondary active transmembrane transporter activity ; GO:0015291' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-asparagine transmembrane transporter activity ; GO:0015182', 'L-glutamine transmembrane transporter activity ; GO:0015186' or its children, and 'transmembrane transporter activity ; GO:0022857' or its children and external ontology term 'permease activity ; GO:0015646'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-isoleucine transmembrane transporter activity ; GO:0015188', 'L-leucine transmembrane transporter activity ; GO:0015190', 'L-valine transmembrane transporter activity ; GO:0005304', and 'transmembrane transporter activity ; GO:0022857' or its children and external ontology term 'permease activity ; GO:0015646'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'metal ion transmembrane transporter activity ; GO:0046873' or its children and 'solute:hydrogen symporter activity ; GO:0015295' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'metal ion transmembrane transporter activity ; GO:0046873' or its children and 'solute:hydrogen symporter activity ; GO:0015295' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'metal ion transmembrane transporter activity ; GO:0046873' or its children and 'solute:hydrogen symporter activity ; GO:0015295' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents more than one molecular function. To update annotations, consider molecular_function terms 'cobalt ion transmembrane transporter activity ; GO:0015087' or its children, 'uptake transmembrane transporter activity ; GO:0015563' or its children, and 'zinc ion transmembrane transporter activity ; GO:0005385' or its children." to "This term was made obsolete because it represents more than one molecular function."
* Changed comment from "This term was made obsolete because it represents more than one molecular function. To update annotations, consider molecular_function terms 'cadmium ion transmembrane transporter activity ; GO:0015086' or its children, 'uptake transmembrane transporter activity ; GO:0015563' or its children, and 'zinc ion transmembrane transporter activity ; GO:0005385' or its children." to "This term was made obsolete because it represents more than one molecular function."
* Changed comment from "This term was made obsolete because it represents more than one molecular function. To update annotations, consider molecular_function terms 'iron ion transmembrane transporter activity ; GO:0005381' or its children, 'uptake transmembrane transporter activity ; GO:0015563' or its children, and 'zinc ion transmembrane transporter activity ; GO:0005385' or its children." to "This term was made obsolete because it represents more than one molecular function."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'monocarboxylic acid transmembrane transporter activity ; GO:0008028' or its children and 'prostaglandin transmembrane transporter activity ; GO:0015132'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'efflux transmembrane transporter activity ; GO:0015562' or its children, 'lactate transmembrane transporter activity ; GO:0015129', 'mevalonate transmembrane transporter activity ; GO:0015130', 'pyruvate transmembrane transporter activity ; GO:0050833' or its children, and 'uptake transmembrane transporter activity ; GO:0015563' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'amino acid transmembrane transporter activity ; GO:0015171' or its children and 'choline transmembrane transporter activity ; GO:0015220' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'antiporter activity ; GO:0015297' or its children, 'dicarboxylic acid transmembrane transporter activity ; GO:0005310' or its children, 'fumarate transmembrane transporter activity ; GO:0015138' or its children, 'malate transmembrane transporter activity ; GO:0015140' or its children, and 'succinate transmembrane transporter activity ; GO:0015141' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-aspartate transmembrane transporter activity ; GO:0015183', 'L-glutamate transmembrane transporter activity ; GO:0005313' or its children, and 'sodium:amino acid symporter activity ; GO:0005283' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'betaine transmembrane transporter activity ; GO:0015199', 'gamma-aminobutyric acid:sodium symporter activity ; GO:0005332', 'L-gamma-aminobutyric acid transmembrane transporter activity ; GO:0015185' or its children, and 'solute:sodium symporter activity ; GO:0015370' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'transmembrane transporter activity ; GO:0022857' or its children, 'uracil transmembrane transporter activity ; GO:0015210' or its children, and 'uridine transmembrane transporter activity ; GO:0015213' or its children and external ontology term 'permease activity ; GO:0015646'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. To update annotations, consider cellular_component term 'ATP-binding cassette (ABC) transporter complex ; GO:0043190' or its children and molecular_function term 'ATPase activity, coupled to transmembrane movement of substances ; GO:0042626' or its children." to "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping."
* Changed comment from "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. To update annotations, consider cellular_component term 'ATP-binding cassette (ABC) transporter complex ; GO:0043190' or its children and molecular_function term 'ATPase activity, coupled to transmembrane movement of substances ; GO:0042626' or its children." to "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping."
* Changed comment from "This term was made obsolete because it describes a gene product and it contains both component and function information. To update annotations, consider cellular_component term 'peroxisome ; GO:0005777' or its children and molecular_function term 'fatty acyl transporter activity ; GO:0015246' or its children." to "This term was made obsolete because it describes a gene product and it contains both component and function information."
* Changed comment from "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping. To update annotations, consider cellular_component term 'ATP-binding cassette (ABC) transporter complex ; GO:0043190' or its children and molecular_function term 'ATPase activity, coupled to transmembrane movement of substances ; GO:0042626' or its children." to "This term was made obsolete because ABC transporters are a protein family rather than a functional grouping."
* Changed comment from "This term was made obsolete because it is a redundant grouping term based on a TC-DB classification. To update annotations, consider molecular_function terms 'hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553' and 'sodium-exporting ATPase activity, phosphorylative mechanism ; GO:0008554'." to "This term was made obsolete because it is a redundant grouping term based on a TC-DB classification."
* Changed comment from "This term was made obsolete because it refers to a bifunctional gene product. To update annotations, consider molecular_function terms 'sodium-transporting ATP synthase activity, rotational mechanism ; GO:0046932' and 'sodium-transporting ATPase activity, rotational mechanism ; GO:0046962'." to "This term was made obsolete because it refers to a bifunctional gene product."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'endosome ; GO:0005768' or its children and molecular_function term 'oligosaccharide transmembrane transporter activity ; GO:0015157' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process terms 'cytolysis ; GO:0019835' or its children, 'pathogenesis ; GO:0009405', and 'pore complex biogenesis ; GO:0046931', cellular_component term 'pore complex ; GO:0046930' or its children, and molecular_function terms 'receptor binding ; GO:0005102' or its children, 'structural molecule activity ; GO:0005198' or its children, and 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process terms 'pathogenesis ; GO:0009405' and 'pore complex biogenesis ; GO:0046931', cellular_component term 'pore complex ; GO:0046930' or its children, and molecular_function terms 'channel activity ; GO:0015267' or its children and 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it refers to a class of proteins and a biological process rather than a molecular function. To update annotations, consider biological_process term 'pilus biogenesis ; GO:0009297' or its children and molecular_function terms 'protein binding, bridging ; GO:0030674' or its children and 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it refers to a class of proteins and a biological process rather than a molecular function."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider cellular_component term 'cell outer membrane ; GO:0009279' or its children and molecular_function term 'porin activity ; GO:0015288' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider cellular_component term 'integral to cell outer membrane ; GO:0045203' and molecular_function term 'protein transporter activity ; GO:0008565' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'hemolysis by symbiont of host red blood cells ; GO:0019836'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-serine transmembrane transporter activity ; GO:0015194', 'L-threonine transmembrane transporter activity ; GO:0015195' or its children, and 'sodium:amino acid symporter activity ; GO:0005283' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it is a redundant grouping term. To update annotations, consider molecular_function terms 'amino acid transmembrane transporter activity ; GO:0015171' or its children and 'aromatic amino acid transmembrane transporter activity ; GO:0015173' or its children and external ontology term 'amino acid permease activity ; GO:0015359'." to "This term was made obsolete because it is a redundant grouping term."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'azole:hydrogen antiporter activity ; GO:0045119' or its children, 'bicyclomycin transporter activity ; GO:0015545', and 'sulfathiazole transporter activity ; GO:0015546'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a gene product rather than a single discrete molecular function. To update annotations, consider molecular_function terms 'L-arabinose transmembrane transporter activity ; GO:0015147' or its children, 'solute:hydrogen antiporter activity ; GO:0015299' or its children, and 'sugar transmembrane transporter activity ; GO:0051119' or its children." to "This term was made obsolete because it represents a gene product rather than a single discrete molecular function."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, use molecular_function terms 'carbonyl cyanide m-chlorophenylhydrazone transporter activity ; GO:0015549', 'drug:hydrogen antiporter activity ; GO:0015307', 'nalidixic acid transporter activity ; GO:0015547', and 'organomercurial transporter activity ; GO:0015548'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'betaine transmembrane transporter activity ; GO:0015199', 'glycine transmembrane transporter activity ; GO:0015187' or its children, 'L-proline transmembrane transporter activity ; GO:0015193' or its children, 'solute:cation symporter activity ; GO:0015294' or its children, 'solute:hydrogen symporter activity ; GO:0015295' or its children, and 'solute:sodium symporter activity ; GO:0015370' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents two molecular functions. To update annotations, consider molecular_function terms 'glucose transmembrane transporter activity ; GO:0005355' or its children, 'lactose transmembrane transporter activity ; GO:0015155' or its children, and 'sugar efflux transmembrane transporter activity ; GO:0015542'." to "This term was made obsolete because it represents two molecular functions."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'gluconate transmembrane transporter activity ; GO:0015128' or its children, 'L-idonate transmembrane transporter activity ; GO:0015568', and 'solute:hydrogen symporter activity ; GO:0015295' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'betaine transmembrane transporter activity ; GO:0015199', 'glycine transmembrane transporter activity ; GO:0015187' or its children, 'L-proline transmembrane transporter activity ; GO:0015193' or its children, and 'quaternary-ammonium-compound-transporting ATPase activity ; GO:0015418'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'arginine transmembrane transporter activity ; GO:0015181' or its children, 'L-histidine transmembrane transporter activity ; GO:0005290' or its children, 'L-lysine transmembrane transporter activity ; GO:0015189' or its children, 'L-ornithine transmembrane transporter activity ; GO:0000064' or its children, and 'polar-amino acid-transporting ATPase activity ; GO:0015426' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-aspartate transmembrane transporter activity ; GO:0015183', 'L-glutamate transmembrane transporter activity ; GO:0005313' or its children, and 'polar-amino acid-transporting ATPase activity ; GO:0015426' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-cystine transmembrane transporter activity ; GO:0015184' or its children, 'L-diaminopimelate transmembrane transporter activity ; GO:0015626', and 'polar-amino acid-transporting ATPase activity ; GO:0015426' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'L-isoleucine transmembrane transporter activity ; GO:0015188', 'L-leucine transmembrane transporter activity ; GO:0015190', 'L-valine transmembrane transporter activity ; GO:0005304', and 'nonpolar-amino acid-transporting ATPase activity ; GO:0015425'." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a multifunctional gene product. To update annotations, consider molecular_function terms 'galactose transmembrane transporter activity ; GO:0005354' or its children, 'glucose transmembrane transporter activity ; GO:0005355' or its children, 'methylgalactoside transmembrane transporter activity ; GO:0015592', and 'secondary active transmembrane transporter activity ; GO:0015291' or its children." to "This term was made obsolete because it represents a multifunctional gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'protein-transmembrane transporting ATPase activity ; GO:0015462' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use biological_process term 'pathogenesis ; GO:0009405' and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a class of gene products and not a molecular function. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children." to "This term was made obsolete because it represents a class of gene products and not a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a function distinct from its parent term. To update annotations, use molecular_function term 'toxin binding ; GO:0015643'." to "This term was made obsolete because it does not represent a function distinct from its parent term."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'cytolysis ; GO:0019835' or its children and molecular_function term 'protein transporter activity ; GO:0008565' or its children." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'cofactor transport ; GO:0051181' or its children and 'vitamin transport ; GO:0051180' or its children." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it does not describe a molecular function. To update annotations, use molecular_function term 'electron carrier activity ; GO:0009055'." to "This term was made obsolete because it does not describe a molecular function."
* Changed comment from "This term was made obsolete because it represents a passive process which occurs without the aid of gene products. To update annotations, consider biological_process term 'proton transport ; GO:0015992' or its children." to "This term was made obsolete because it represents a passive process which occurs without the aid of gene products."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, use molecular_function term 'antiporter activity ; GO:0015297'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, use molecular_function term 'symporter activity ; GO:0015293'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a molecular function rather than a biological process. To update annotations, use molecular_function term 'uniporter activity ; GO:0015292'." to "This term was made obsolete because it represents a molecular function rather than a biological process."
* Changed comment from "This term was made obsolete because it refers to a class of proteins. To update annotations, consider biological_process terms 'phototransduction, visible light ; GO:0007603' and 'UV-A, blue light phototransduction ; GO:0009588', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function terms '3,4-didehydroretinal binding ; GO:0046876', 'photoreceptor activity ; GO:0009881' or its children, and 'retinal binding ; GO:0016918' or its children." to "This term was made obsolete because it refers to a class of proteins."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function term 'endopeptidase activity ; GO:0004175' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function term 'endopeptidase activity ; GO:0004175' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it refers to a gene product. To update annotations, consider biological_process term 'negative regulation of juvenile hormone biosynthetic process ; GO:0045968' and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it refers to a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process terms 'positive regulation of gluconeogenesis ; GO:0045722', 'positive regulation of glucose import ; GO:0046326', 'positive regulation of lipid biosynthetic process ; GO:0046889' or its children, 'positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ; GO:0045935' or its children, and 'positive regulation of protein biosynthetic process ; GO:0045727' or its children and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it contains both process and function information. To update annotations, use biological_process terms 'translation ; GO:0006412' and 'translational initiation ; GO:0006413' and molecular_function terms 'GTPase activity ; GO:0003924' and 'translation initiation factor activity ; GO:0003743'." to "This term was made obsolete because it contains both process and function information."
* Changed comment from "This term was made obsolete because it contains both process and function information. To update annotations, use biological_process terms 'translation ; GO:0006412' and 'translational elongation ; GO:0006414' and molecular_function terms 'GTPase activity ; GO:0003924' and 'translation elongation factor activity ; GO:0003746'." to "This term was made obsolete because it contains both process and function information."
* Changed comment from "This term was made obsolete because it contains both process and function information. To update annotations, use biological_process terms 'translation ; GO:0006412' and 'translational termination ; GO:0006415' and molecular_function terms 'GTPase activity ; GO:0003924' and 'translation termination factor activity ; GO:0008079'." to "This term was made obsolete because it contains both process and function information."
* Changed comment from "This term was made obsolete because it refers to a biological process. To update annotations, consider biological_process terms 'homoiothermy ; GO:0042309' and 'response to freezing ; GO:0050826' and molecular_function term 'ice binding ; GO:0050825'." to "This term was made obsolete because it refers to a biological process."
* Changed comment from "This term was made obsolete because it refers to a biological process. To update annotations, consider biological_process terms 'homoiothermy ; GO:0042309' and 'response to freezing ; GO:0050826' and molecular_function term 'ice binding ; GO:0050825'." to "This term was made obsolete because it refers to a biological process."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'vesicle-mediated transport ; GO:0016192' or its children." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function terms '1-phosphatidylinositol-3-kinase activity ; GO:0016303', 'phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934', and 'phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider molecular_function terms '1-phosphatidylinositol-3-kinase activity ; GO:0016303', 'phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934', and 'phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, use molecular_function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it is a redundant grouping term with only one child. To update annotations, consider molecular_function term 'inositol trisphosphate phosphatase activity ; GO:0046030' or its children." to "This term was made obsolete because it is a redundant grouping term with only one child."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'microtubule motor activity ; GO:0003777'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents involvement in a biological process. To update annotations, use biological_process term 'regulation of apoptosis ; GO:0042981'." to "This term was made obsolete because it represents involvement in a biological process."
* Changed comment from "This term was made obsolete because it is a redundant grouping term. To update annotations, use cellular_component term 'collagen ; GO:0005581'." to "This term was made obsolete because it is a redundant grouping term."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'cytoskeletal anchoring ; GO:0007016'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process terms 'calcium-independent cell-cell adhesion ; GO:0016338' or its children and 'calcium-independent cell-matrix adhesion ; GO:0007161', cellular_component term 'integral to membrane ; GO:0016021' or its children, and molecular_function term 'protein binding ; GO:0005515' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to drug ; GO:0042493'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to insecticide ; GO:0017085'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to carbamate ; GO:0046681'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to cyclodiene ; GO:0046682'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to DDT ; GO:0046680'." to "This term was made obsolete because 'resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to organophosphorus ; GO:0046683'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to pyrethroid ; GO:0046684'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function terms 'hydrogen ion transporting ATP synthase activity, rotational mechanism ; GO:0046933' and 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function terms 'sodium-transporting ATP synthase activity, rotational mechanism ; GO:0046932' and 'sodium-transporting ATPase activity, rotational mechanism ; GO:0046962'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents involvement in a biological process. To update annotations, use biological_process term 'induction of apoptosis ; GO:0006917'." to "This term was made obsolete because it represents involvement in a biological process."
* Changed comment from "This term was made obsolete because it refers to a protein sequence feature. To update annotations, consider biological_process term 'intein-mediated protein splicing ; GO:0016539' or its children and molecular_function term 'endonuclease activity ; GO:0004519' or its children." to "This term was made obsolete because it refers to a protein sequence feature."
* Changed comment from "This term was made obsolete because it has been replaced by more specific terms. To update annotations, consider biological_process term 'nucleosome assembly ; GO:0006334' or its children." to "This term was made obsolete because it has been replaced by more specific terms."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on the aldehyde or oxo group of donors ; GO:0016903' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on the CH-NH2 group of donors ; GO:0016638' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on the CH-NH group of donors ; GO:0016645' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was a grouping term taken from EC that no longer has any functions associated with it. To update annotations, consider molecular_function terms 'flavin reductase activity ; GO:0042602' and 'FMN reductase activity ; GO:0008752'." to "This term was made obsolete because it was a grouping term taken from EC that no longer has any functions associated with it."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on NADH or NADPH ; GO:0016651' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on other nitrogenous compounds as donors ; GO:0016661' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on sulfur group of donors ; GO:0016667' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on heme group of donors ; GO:0016675' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on diphenols and related substances as donors ; GO:0016679' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it represents a bifunctional gene product. To update annotations, consider molecular_function terms 'catalase activity ; GO:0004096' and 'peroxidase activity ; GO:0004601' or its children." to "This term was made obsolete because it represents a bifunctional gene product."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on hydrogen as donor ; GO:0016695' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on single donors with incorporation of molecular oxygen ; GO:0016701' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on CH or CH2 groups ; GO:0016725' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it represents a cellular component. To update annotations, use cellular_component term 'iron-iron nitrogenase complex ; GO:0016611' and molecular_function term 'nitrogenase activity ; GO:0016163'." to "This term was made obsolete because it represents a cellular component."
* Changed comment from "This term was made obsolete because it represents a cellular component. To update annotations, use cellular_component term 'molybdenum-iron nitrogenase complex ; GO:0016612' and molecular_function term 'nitrogenase activity ; GO:0016163'." to "This term was made obsolete because it represents a cellular component."
* Changed comment from "This term was made obsolete because it represents a cellular component. To update annotations, use cellular_component term 'vanadium-iron nitrogenase complex ; GO:0016613' and molecular_function term 'nitrogenase activity ; GO:0016163'." to "This term was made obsolete because it represents a cellular component."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity ; GO:0016491' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'transferase activity, transferring glycosyl groups ; GO:0016757' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'transferase activity, transferring nitrogenous groups ; GO:0016769' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it incorporates process information. To update annotations, use molecular_function term 'hydrolase activity, acting on acid anhydrides ; GO:0016817'." to "This term was made obsolete because it incorporates process information."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'carbon-carbon lyase activity ; GO:0016830' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'carbon-oxygen lyase activity ; GO:0016835' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'carbon-nitrogen lyase activity ; GO:0016840' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'lyase activity ; GO:0016829' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'racemase and epimerase activity ; GO:0016854' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'intramolecular oxidoreductase activity ; GO:0016860' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'intramolecular transferase activity ; GO:0016866' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'isomerase activity ; GO:0016853' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'ligase activity, forming carbon-nitrogen bonds ; GO:0016879' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it describes a gene product. To update annotations, consider biological_process term 'JNK cascade ; GO:0007254' or its children and molecular_function terms 'protein serine/threonine kinase activity ; GO:0004674' or its children and 'signal transducer activity ; GO:0004871' or its children." to "This term was made obsolete because it describes a gene product."
* Changed comment from "This term was made obsolete because it describes a gene product. To update annotations, consider biological_process term 'JNK cascade ; GO:0007254' or its children and molecular_function terms 'protein serine/threonine kinase activity ; GO:0004674' or its children and 'signal transducer activity ; GO:0004871' or its children." to "This term was made obsolete because it describes a gene product."
* Changed comment from "This term was made obsolete because there are no known gene products that would be described as 'SAP kinase 5', and the term name implies that it refers to a gene product. To update annotations, consider biological_process term 'JNK cascade ; GO:0007254' or its children and molecular_function terms 'protein serine/threonine kinase activity ; GO:0004674' or its children and 'signal transducer activity ; GO:0004871' or its children." to "This term was made obsolete because there are no known gene products that would be described as 'SAP kinase 5', and the term name implies that it refers to a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'positive regulation of follicle-stimulating hormone secretion ; GO:0046881' and molecular_function term 'transforming growth factor beta receptor binding ; GO:0005160' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'negative regulation of follicle-stimulating hormone secretion ; GO:0046882' and molecular_function term 'transforming growth factor beta receptor binding ; GO:0005160' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function term 'thyroid hormone receptor binding ; GO:0046966'." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it describes a gene product and not a molecular function. To update annotations, consider molecular_function terms 'protein binding ; GO:0005515' or its children and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it describes a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'protein binding ; GO:0005515' or its children and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'oxygen transporter activity ; GO:0005344'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'oxygen transporter activity ; GO:0005344'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'endopeptidase inhibitor activity ; GO:0004866'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it describes the binding of myosin phosphatase to myosin, which is not a molecular function. To update annotations, consider molecular_function terms 'myosin binding ; GO:0017022' or its children and 'myosin phosphatase activity ; GO:0017018'." to "This term was made obsolete because it describes the binding of myosin phosphatase to myosin, which is not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'protein binding ; GO:0005515' or its children and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'protein stabilization ; GO:0050821'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it contains both component and function information. To update annotations, consider biological_process term 'protein stabilization ; GO:0050821' and cellular_component term 'lysosome ; GO:0005764' or its children." to "This term was made obsolete because it contains both component and function information."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'protein stabilization ; GO:0050821'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process terms 'positive regulation of hormone biosynthetic process ; GO:0046886' or its children and 'positive regulation of hormone secretion ; GO:0046887' or its children and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component term 'insulin-like growth factor binding protein complex ; GO:0016942' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function. To update annotations, consider biological_process terms 'protein complex assembly ; GO:0006461' or its children and 'tubulin folding ; GO:0007021' or its children and molecular_function term 'unfolded protein binding ; GO:0051082'." to "This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a molecular function and the term name appears to make no sense. To update annotations, consider molecular_function term 'enzyme binding ; GO:0019899' or its children." to "This term was made obsolete because it does not represent a molecular function and the term name appears to make no sense."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to arsenic ; GO:0046685'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to antibiotic ; GO:0046677'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to toxin ; GO:0009636'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents involvement in a biological process. To update annotations, use biological_process term 'negative regulation of protein biosynthetic process ; GO:0017148'." to "This term was made obsolete because it represents involvement in a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product and not a molecular function. To update annotations, consider molecular_function terms 'protein binding ; GO:0005515' or its children and 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product and not a molecular function."
* Changed comment from "This term was made obsolete because it represents a gene product with two different activities. To update annotations, consider molecular_function term 'GMP 5'-nucleotidase activity ; GO:0050484'." to "This term was made obsolete because it represents a gene product with two different activities."
* Changed comment from "This term was made obsolete because it was replaced with more appropriate terms. To update annotations, consider biological_process term 'peptidyl-D-alanine racemization ; GO:0019122' or its children." to "This term was made obsolete because it was replaced with more appropriate terms."
* Changed comment from "This term was made obsolete because the three-iron three-sulfur cluster is now thought not to exist except possibly as an intermediate form. To update annotations, consider biological_process terms 'iron incorporation into metallo-sulfur cluster ; GO:0018283' or its children and 'peptidyl-cysteine modification ; GO:0018198' or its children." to "This term was made obsolete because the three-iron three-sulfur cluster is now thought not to exist except possibly as an intermediate form."
* Changed comment from "This term was made obsolete because the prismane 6Fe-6S cluster is now thought not to exist. To update annotations, consider biological_process terms 'iron incorporation into metallo-sulfur cluster ; GO:0018283' or its children and 'peptidyl-cysteine modification ; GO:0018198' or its children." to "This term was made obsolete because the prismane 6Fe-6S cluster is now thought not to exist."
* Removed comment
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider biological_process term 'protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine ; GO:0018097'." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it is not clear that this process occurs. To update annotations, consider biological_process term 'amino acid metabolic process ; GO:0006520' or its children." to "This term was made obsolete because it is not clear that this process occurs."
* Changed comment from "This term was made obsolete because its use of 'and' was causing violations to the true-path rule. To update annotations, consider biological_process terms 'methionine metabolic process ; GO:0006555' or its children and 'threonine metabolic process ; GO:0006566' or its children." to "This term was made obsolete because its use of 'and' was causing violations to the true-path rule."
* Changed comment from "This term was made obsolete because the parent terms cover its function. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because the parent terms cover its function."
* Changed comment from "This term was made obsolete because it represents a single gene product and not a complex. To update annotations, consider cellular_component term 'mitochondrial outer membrane ; GO:0005741' or its children." to "This term was made obsolete because it represents a single gene product and not a complex."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function terms 'endodeoxyribonuclease activity ; GO:0004520' or its children and 'endoribonuclease activity ; GO:0004521' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it does not represent a true molecular function. To update annotations, consider biological_process term 'DNA replication ; GO:0006260' or its children." to "This term was made obsolete because it does not represent a true molecular function."
* Changed comment from "This term was made obsolete because it represents a type of gene product and not a location or complex. To update annotations, consider cellular_component term 'viral envelope ; GO:0019031'." to "This term was made obsolete because it represents a type of gene product and not a location or complex."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'viral envelope fusion with host membrane ; GO:0019064' and molecular_function term 'cell adhesion molecule binding ; GO:0050839' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider biological_process term 'modification by virus of host cell mRNA translation ; GO:0019057' or its children and molecular_function term '5'-3' exoribonuclease activity ; GO:0004534'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it represents involvement in a process. To update annotations, consider biological_process term 'regulation of liquid surface tension ; GO:0050828'." to "This term was made obsolete because it represents involvement in a process."
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use biological_process term 'glutamate biosynthetic process ; GO:0006537' and molecular_function term 'glutamate dehydrogenase [NAD(P)+] activity ; GO:0004353'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it refers to a molecular function. To update annotations, use biological_process term 'glutamate biosynthetic process ; GO:0006537' and molecular_function term 'glutamate synthase (NADPH) activity ; GO:0004355'." to "This term was made obsolete because it refers to a molecular function."
* Changed comment from "This term was made obsolete because it refers to a one-step pathway. To update annotations, use biological_process term 'tryptophan catabolic process ; GO:0006569' and molecular_function term 'tryptophanase activity ; GO:0009034'." to "This term was made obsolete because it refers to a one-step pathway."
* Changed comment from "This term was made obsolete because hydrolysis is a reaction. To update annotations, consider molecular_function term 'beta-galactosidase activity ; GO:0004565'." to "This term was made obsolete because hydrolysis is a reaction."
* Changed comment from "This term was made obsolete because it represents a process, NAD dephosphorylation, that does not exist. To update annotations, consider biological_process terms 'NAD metabolic process ; GO:0019674' or its children and 'NADP metabolic process ; GO:0006739' or its children." to "This term was made obsolete because it represents a process, NAD dephosphorylation, that does not exist."
* Changed comment from "This term was made obsolete because it is an unnecessary grouping term. To update annotations, consider molecular_function terms 'high affinity IgE receptor activity ; GO:0019768' and 'high affinity IgG receptor activity ; GO:0019771'." to "This term was made obsolete because it is an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it is undefined and is an unnecessary grouping term. To update annotations, consider molecular_function terms 'low affinity IgE receptor activity ; GO:0019769' and 'low affinity IgG receptor activity ; GO:0019772'." to "This term was made obsolete because it is undefined and is an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. To update annotations, consider molecular_function term 'small conjugating protein-specific protease activity ; GO:0019783' or its children." to "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature."
* Changed comment from "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. To update annotations, consider molecular_function term 'small conjugating protein-specific protease activity ; GO:0019783' or its children." to "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature."
* Changed comment from "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. To update annotations, consider molecular_function term 'small conjugating protein-specific protease activity ; GO:0019783' or its children." to "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature."
* Changed comment from "This term was made obsolete because it represents a molecule and not a location or complex. To update annotations, consider cellular_component term 'B cell receptor complex ; GO:0019815'." to "This term was made obsolete because it represents a molecule and not a location or complex."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to cadmium ion ; GO:0046686'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to chromate ; GO:0046687'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to mercury ion ; GO:0046689'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process terms 'homoiothermy ; GO:0042309' and 'pathogenesis ; GO:0009405' and molecular_function term 'ice binding ; GO:0050825'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to herbicide ; GO:0009635'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405', cellular_component term 'intracellular ; GO:0005622' or its children, and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405', cellular_component term 'extracellular region ; GO:0005576' or its children, and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405' and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405' and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'negative regulation of neurotransmitter secretion ; GO:0046929' or its children and molecular_function term 'calcium channel inhibitor activity ; GO:0019855'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a class of gene products. To update annotations, consider biological_process term 'pathogenesis ; GO:0009405' and molecular_function term 'toxin receptor binding ; GO:0050827'." to "This term was made obsolete because it represents a class of gene products."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to tellurium ion ; GO:0046690'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to bacteriocin ; GO:0046678'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to streptomycin ; GO:0046679'." to "This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it does not represent a true molecular function. To update annotations, use biological_process term 'negative regulation of DNA replication ; GO:0008156'." to "This term was made obsolete because it does not represent a true molecular function."
* Changed comment from "This term was made obsolete because it did not adequately describe phosphoinositide-mediated signaling. To update annotations, consider biological_process terms 'inositol lipid-mediated signaling ; GO:0048017', 'inositol phosphate-mediated signaling ; GO:0048016' or its children, and 'phosphoinositide-mediated signaling ; GO:0048015' or its children." to "This term was made obsolete because it did not adequately describe phosphoinositide-mediated signaling."
* Changed comment from "This term was made obsolete because it does not reflect an accurate biological process, as sumoylation of a protein does not lead to catabolism of that protein. To update annotations, consider biological_process terms 'protein desumoylation ; GO:0016926' and 'protein sumoylation ; GO:0016925' or its children." to "This term was made obsolete because it does not reflect an accurate biological process, as sumoylation of a protein does not lead to catabolism of that protein."
* Changed comment from "This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction. To update annotations, consider biological_process term 'protein neddylation ; GO:0045116'." to "This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction."
* Changed name of GO:0022001 from "negative regulation of anterior neural cell fate of the neural plate" to "negative regulation of anterior neural cell fate commitment of the neural plate"
* Changed definition of GO:0022001 from "Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a cell from adopting an anterior neural cell fate." to "Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate."
* Added definition dbxref GOC:tb to GO:0022001
* Added synonym "negative regulation of anterior neural cell fate of the neural plate" to GO:0022001
* Added general dbxref GOC:tb to synonym negative regulation of anterior neural cell fate of the neural plate of GO:0022001
* Added general dbxref GOC:dph to synonym negative regulation of anterior neural cell fate of the neural plate of GO:0022001
* Changed synonym scope of GO:0022001 from "Related" to "Exact"
* Copied GO:0022001 to GO:0010454 with type OBO_REL:is_a
* Changed name of GO:0022002 from "Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" to "Wnt receptor signaling involved in negative regulation of anterior neural cell fate commitment of the neural plate"
* Changed definition of GO:0022002 from "The series of molecular signals that stops, prevents or reduces the frequency, rate or extent of the directed movement of a cell from adopting an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell." to "The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell."
* Added definition dbxref GOC:tb to GO:0022002
* Added synonym "Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" to GO:0022002
* Added general dbxref GOC:tb to synonym Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate of GO:0022002
* Added general dbxref GOC:dph to synonym Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate of GO:0022002
* Changed synonym scope of GO:0022002 from "Related" to "Exact"
* Changed name of GO:0022003 from "fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" to "fgf receptor signaling involved in negative regulation of anterior neural cell fate commitment of the neural plate"
* Changed definition of GO:0022003 from "The series of molecular signals that stops, prevents or reduces the frequency, rate or extent of the directed movement of a cell from adopting an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." to "The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands."
* Added definition dbxref GOC:tb to GO:0022003
* Added synonym "fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" to GO:0022003
* Added general dbxref GOC:tb to synonym fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate of GO:0022003
* Added general dbxref GOC:dph to synonym fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate of GO:0022003
* Changed synonym scope of GO:0022003 from "Related" to "Exact"
* Changed comment from "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information). To update annotations, consider biological_process term 'cellular metal ion homeostasis ; GO:0006875' or its children." to "This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information)."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'complement activation ; GO:0006956' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, use cellular_component term 'proteinaceous extracellular matrix ; GO:0005578' and molecular_function terms 'cell adhesion molecule binding ; GO:0050839', 'extracellular matrix binding ; GO:0050840', and 'protein binding, bridging ; GO:0030674'." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a true molecular function. To update annotations, use biological_process term 'DNA unwinding during replication ; GO:0006268'." to "This term was made obsolete because it does not represent a true molecular function."
* Deleted GO:0030049 --OBO_REL:is_a--> GO:0006936
* Copied GO:0030049 to GO:0006936 with type part_of
* Changed comment from "This term was made obsolete because it represents a gene product and not a function. To update annotations, use molecular_function terms 'FK506 binding ; GO:0005528' and 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755'." to "This term was made obsolete because it represents a gene product and not a function."
* Changed comment from "This term was made obsolete because it describes a gene product. To update annotations, use molecular_function term 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755'." to "This term was made obsolete because it describes a gene product."
* Changed comment from "This term was made obsolete because it does not represent a molecular function. To update annotations, consider molecular_function terms 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755' or its children and 'receptor activity ; GO:0004872' or its children." to "This term was made obsolete because it does not represent a molecular function."
* Changed comment from "This term was made obsolete because it was defined inaccurately. To update annotations, consider cellular_component term '1-2nm peptidoglycan-based cell wall ; GO:0009276'." to "This term was made obsolete because it was defined inaccurately."
* Changed comment from "This term was made obsolete because it was defined inaccurately. To update annotations, consider cellular_component term '1-2nm peptidoglycan-based cell wall ; GO:0009276'." to "This term was made obsolete because it was defined inaccurately."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use molecular_function term 'electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity ; GO:0045158'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'electron carrier activity ; GO:0009055' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because more specific terms were created. To update annotations, consider biological_process terms 'lytic viral release ; GO:0019077' or its children and 'viral infectious cycle ; GO:0019058' or its children." to "This term was made obsolete because more specific terms were created."
* Changed comment from "This term was made obsolete because thylakoids are not found in organisms of the Phylum Proteobacteria. To update annotations, consider cellular_component term 'chromatophore ; GO:0042716' or its children." to "This term was made obsolete because thylakoids are not found in organisms of the Phylum Proteobacteria."
* Changed comment from "This term was made obsolete because the 'complex' it refers to contains only one gene product. To update annotations, use cellular_component term 'PSII associated light-harvesting complex II, core complex ; GO:0009655'." to "This term was made obsolete because the 'complex' it refers to contains only one gene product."
* Changed comment from "This term was made obsolete because the 'complex' it refers to contains only one gene product. To update annotations, use cellular_component term 'PSII associated light-harvesting complex II, core complex ; GO:0009655'." to "This term was made obsolete because the 'complex' it refers to contains only one gene product."
* Changed comment from "This term was made obsolete because the 'complex' it refers to contains only one gene product. To update annotations, use cellular_component term 'PSII associated light-harvesting complex II, core complex ; GO:0009655'." to "This term was made obsolete because the 'complex' it refers to contains only one gene product."
* Changed comment from "This term was made obsolete because it represents a an abnormal process that is harmful to the organism. To update annotations, consider biological_process term 'immune response ; GO:0006955' or its children." to "This term was made obsolete because it represents a an abnormal process that is harmful to the organism."
* Copied GO:0030146 to GO:0007588 with type OBO_REL:is_a
* Changed comment from "This term was made obsolete because it represents a molecular function. To update annotations, use biological_process term 'transport ; GO:0006810' and molecular_function term 'solute:solute antiporter activity ; GO:0015300'." to "This term was made obsolete because it represents a molecular function."
* Changed comment from "This term was made obsolete because it represents a function rather than a process. To update annotations, use biological_process terms 'calcium ion transport ; GO:0006816' and 'sodium ion transport ; GO:0006814' and consider molecular_function term 'calcium:sodium antiporter activity ; GO:0005432'." to "This term was made obsolete because it represents a function rather than a process."
* Changed comment from "This term was made obsolete because it describes a cellular component rather than a molecular function. To update annotations, use cellular_component term 'small nucleolar ribonucleoprotein complex ; GO:0005732'." to "This term was made obsolete because it describes a cellular component rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a cellular component rather than a molecular function. To update annotations, use cellular_component term 'small cytoplasmic ribonucleoprotein complex ; GO:0030531'." to "This term was made obsolete because it describes a cellular component rather than a molecular function."
* Changed comment from "This term was made obsolete because it describes a biological process. To update annotations, consider biological_process term 'mRNA cleavage ; GO:0006379' or its children." to "This term was made obsolete because it describes a biological process."
* Changed comment from "This term was made obsolete because it describes a cellular component. To update annotations, use cellular_component term 'mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847' and consider biological_process terms 'mRNA cleavage ; GO:0006379' or its children and 'mRNA polyadenylation ; GO:0006378'." to "This term was made obsolete because it describes a cellular component."
* Changed comment from "This term was made obsolete because it describes a cellular component. To update annotations, use cellular_component term 'mRNA cleavage stimulating factor complex ; GO:0005848' and consider biological_process term 'mRNA cleavage ; GO:0006379' or its children." to "This term was made obsolete because it describes a cellular component."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process term 'symbiosis, encompassing mutualism through parasitism ; GO:0044403' or its children." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider molecular_function term 'protein binding, bridging ; GO:0030674' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because the entire branch of the ontology was changed. To update annotations, use biological_process term 'microtubule depolymerization ; GO:0007019'." to "This term was made obsolete because the entire branch of the ontology was changed."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it is a gene product specific term. To update annotations, use biological_process term 'pheromone-dependent signal transduction during conjugation with cellular fusion ; GO:0000750'." to "This term was made obsolete because it is a gene product specific term."
* Changed comment from "This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'. To update annotations, use biological_process term 'cell aging ; GO:0007569'." to "This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'."
* Changed comment from "This term was made obsolete because it reflected a trait or phenotype. To update annotations, consider biological_process term 'chromatin silencing at silent mating-type cassette ; GO:0030466'." to "This term was made obsolete because it reflected a trait or phenotype."
* Changed comment from "This term was made obsolete because a more correct term has been created. To update annotations, consider biological_process term 'autophagic cell death ; GO:0048102' or its children." to "This term was made obsolete because a more correct term has been created."
* Changed comment from "This term was made obsolete because a sensu term was not needed. To update annotations, use biological_process term 'spore germination ; GO:0009847'." to "This term was made obsolete because a sensu term was not needed."
* Changed comment from "This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept. To update annotations, consider biological_process terms 'spindle organization and biogenesis ; GO:0007051' or its children and 'spindle pole body organization and biogenesis ; GO:0051300' or its children." to "This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept."
* Changed comment from "This term was made obsolete because a muscle fiber is a cell type rather than a cell component. To update annotations, use cellular_component term 'contractile fiber ; GO:0043292'." to "This term was made obsolete because a muscle fiber is a cell type rather than a cell component."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, use biological_process term 'adult feeding behavior ; GO:0008343'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'regulation of coenzyme metabolic process ; GO:0051196' or its children and 'regulation of prosthetic group metabolic process ; GO:0051199' or its children." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'long-day photoperiodism ; GO:0048571' or its children." to "This term was made obsolete because it was wrongly defined."
* Changed comment from "This term was made obsolete because it was wrongly defined. To update annotations, consider biological_process term 'short-day photoperiodism ; GO:0048572' or its children." to "This term was made obsolete because it was wrongly defined."
* Deleted synonym "apelin-like receptor" from GO:0031704
* Deleted GO:0031935 --OBO_REL:is_a--> GO:0050789
* Copied GO:0031935 to GO:0031445 with type OBO_REL:is_a
* Copied GO:0031936 to GO:0031452 with type OBO_REL:is_a
* Copied GO:0031937 to GO:0031453 with type OBO_REL:is_a
* Changed name of GO:0032221 from "Clr6 histone deacetylase complex" to "Clr6 histone deacetylase complex II'"
* Changed definition of GO:0032221 from "A eukaryotically conserved histone deacetylse complex composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; homologs thereof in other species)." to "A eukaryotically conserved histone deacetylse complex which deacetylates histones preferentially in
promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; homologs thereof in other species)."
* Added definition dbxref GOC:vw to GO:0032221
* Added definition dbxref PMID:17450151 to GO:0032221
* Changed name of GO:0040014 from "regulation of body size" to "regulation of multicellular organism growth"
* Added definition dbxref GOC:dph to GO:0040014
* Added definition dbxref GOC:tb to GO:0040014
* Added general dbxref GOC:tb to synonym regulation of body growth of GO:0040014
* Added general dbxref GOC:dph to synonym regulation of body growth of GO:0040014
* Changed synonym scope of GO:0040014 from "Related" to "Exact"
* Added synonym "regulation of body size" to GO:0040014
* Added general dbxref GOC:tb to synonym regulation of body size of GO:0040014
* Added general dbxref GOC:dph to synonym regulation of body size of GO:0040014
* Changed synonym scope of GO:0040014 from "Related" to "Exact"
* Changed name of GO:0040015 from "negative regulation of body size" to "negative regulation of multicellular organism growth"
* Added definition dbxref GOC:dph to GO:0040015
* Added definition dbxref GOC:tb to GO:0040015
* Deleted synonym "down regulation of body size" from GO:0040015
* Deleted synonym "down-regulation of body size" from GO:0040015
* Deleted synonym "downregulation of body size" from GO:0040015
* Deleted synonym "inhibition of body size" from GO:0040015
* Added synonym "negative regulation of body growth" to GO:0040015
* Added general dbxref GOC:tb to synonym negative regulation of body growth of GO:0040015
* Added general dbxref GOC:dph to synonym negative regulation of body growth of GO:0040015
* Changed synonym scope of GO:0040015 from "Related" to "Exact"
* Added synonym "negative regulation of body size" to GO:0040015
* Added general dbxref GOC:tb to synonym negative regulation of body size of GO:0040015
* Added general dbxref GOC:dph to synonym negative regulation of body size of GO:0040015
* Changed synonym scope of GO:0040015 from "Related" to "Exact"
* Changed name of GO:0040018 from "positive regulation of body size" to "positive regulation of multicellular organism growth"
* Added definition dbxref GOC:dph to GO:0040018
* Added definition dbxref GOC:tb to GO:0040018
* Deleted synonym "activation of body size" from GO:0040018
* Deleted synonym "stimulation of body size" from GO:0040018
* Deleted synonym "up regulation of body size" from GO:0040018
* Deleted synonym "up-regulation of body size" from GO:0040018
* Deleted synonym "upregulation of body size" from GO:0040018
* Added synonym "positive regulation of body growth" to GO:0040018
* Added general dbxref GOC:tb to synonym positive regulation of body growth of GO:0040018
* Added general dbxref GOC:dph to synonym positive regulation of body growth of GO:0040018
* Changed synonym scope of GO:0040018 from "Related" to "Exact"
* Added synonym "positive regulation of body size" to GO:0040018
* Added general dbxref GOC:tb to synonym positive regulation of body size of GO:0040018
* Added general dbxref GOC:dph to synonym positive regulation of body size of GO:0040018
* Changed synonym scope of GO:0040018 from "Related" to "Exact"
* Changed comment from "This term was made obsolete because it is contains gene product specific characteristics. To update annotations, consider molecular_function term 'peptidyl-prolyl cis-trans isomerase activity ; GO:0003755' or its children." to "This term was made obsolete because it is contains gene product specific characteristics."
* Changed comment from "This term was made obsolete because it represents a combination of process and function information. To update annotations, use biological_process term 'protein localization ; GO:0008104' and molecular_function term 'transforming growth factor beta receptor binding ; GO:0005160'." to "This term was made obsolete because it represents a combination of process and function information."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'regulation of cell adhesion ; GO:0030155' or its children and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider biological_process term 'negative regulation of cell adhesion ; GO:0007162' or its children and molecular_function term 'receptor binding ; GO:0005102' or its children." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it is a composite term that represents two individual processes. To update annotations, consider biological_process terms 'GPI anchor metabolic process ; GO:0006505' or its children and 'GSI anchor metabolic process ; GO:0042081' or its children." to "This term was made obsolete because it is a composite term that represents two individual processes."
* Changed comment from "This term was made obsolete because it is a composite term that represents two individual processes. To update annotations, consider biological_process terms 'GPI anchor biosynthetic process ; GO:0006506' or its children and 'GSI anchor biosynthetic process ; GO:0042082' or its children." to "This term was made obsolete because it is a composite term that represents two individual processes."
* Changed comment from "This term was made obsolete because it describes a receptor type, and not an activity. To update annotations, consider molecular_function terms 'MHC class Ib receptor activity ; GO:0032394', 'MHC class II receptor activity ; GO:0032395', and 'peptide antigen binding ; GO:0042605' or its children." to "This term was made obsolete because it describes a receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it describes a receptor type, and not an activity. To update annotations, consider molecular_function terms 'MHC class Ib receptor activity ; GO:0032394', 'MHC class II receptor activity ; GO:0032395', and 'peptide antigen binding ; GO:0042605' or its children." to "This term was made obsolete because it describes a receptor type, and not an activity."
* Changed comment from "This term was made obsolete because it is too gene product specific. To update annotations, consider cellular_component term 'ATP-binding cassette (ABC) transporter complex ; GO:0043190' or its children and molecular_function term 'ATPase activity, coupled to transmembrane movement of substances ; GO:0042626' or its children." to "This term was made obsolete because it is too gene product specific."
* Changed comment from "This term was made obsolete because it represents a molecular function and not a biological process. To update annotations, use molecular_function term 'metal chelating activity ; GO:0046911'." to "This term was made obsolete because it represents a molecular function and not a biological process."
* Changed comment from "This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity. To update annotations, consider biological_process term 'symbiosis, encompassing mutualism through parasitism ; GO:0044403' or its children and molecular_function term 'host cell surface receptor binding ; GO:0046789'." to "This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity."
* Changed comment from "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. To update annotations, consider molecular_function term 'small conjugating protein-specific protease activity ; GO:0019783' or its children." to "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature."
* Changed comment from "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature. To update annotations, consider molecular_function term 'small conjugating protein-specific protease activity ; GO:0019783' or its children." to "This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature."
* Changed comment from "This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction. To update annotations, consider biological_process term 'protein neddylation ; GO:0045116'." to "This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'protein homooligomerization ; GO:0051260'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because the definition was incorrect. To update annotations, consider cellular_component term 'generative cell nucleus ; GO:0048555'." to "This term was made obsolete because the definition was incorrect."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use cellular_component term 'keratin filament ; GO:0045095'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use cellular_component term 'keratin filament ; GO:0045095'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, use cellular_component term 'type III intermediate filament ; GO:0045098'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'type III intermediate filament ; GO:0045098'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'type III intermediate filament ; GO:0045098'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because it represents a gene product. To update annotations, consider cellular_component term 'type III intermediate filament ; GO:0045098'." to "This term was made obsolete because it represents a gene product."
* Changed comment from "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process. To update annotations, use biological_process term 'response to copper ion ; GO:0046688'." to "This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process."
* Changed comment from "This term was made obsolete because it represents a gene product rather than a molecular function. To update annotations, consider molecular_function term 'digestive hormone activity ; GO:0046659'." to "This term was made obsolete because it represents a gene product rather than a molecular function."
* Changed comment from "This term was made obsolete because it does not represent a true function. To update annotations, use biological_process term 'regulation of establishment of competence for transformation ; GO:0045304'." to "This term was made obsolete because it does not represent a true function."
* Changed comment from "This term was made obsolete because it does not represent a true function. To update annotations, use biological_process term 'negative regulation of establishment of competence for transformation ; GO:0045808'." to "This term was made obsolete because it does not represent a true function."
* Changed comment from "This term was made obsolete because it does not represent a true function. To update annotations, use biological_process term 'positive regulation of establishment of competence for transformation ; GO:0045809'." to "This term was made obsolete because it does not represent a true function."
* Changed comment from "This term was made obsolete because it represents two functions. To update annotations, consider molecular_function terms 'phosphoserine binding ; GO:0050815' and 'phosphothreonine binding ; GO:0050816'." to "This term was made obsolete because it represents two functions."
* Changed comment from "This term was made obsolete because it represents two activities. To update annotations, use molecular_function terms 'CoB--CoM heterodisulfide reductase activity ; GO:0051912' and 'Methanosarcina-phenazine hydrogenase activity ; GO:0051911'." to "This term was made obsolete because it represents two activities."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, consider biological_process term 'behavioral response to ethanol ; GO:0048149'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term. To update annotations, consider biological_process term 'behavioral response to ether ; GO:0048150'." to "This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term."
* Changed comment from "This term was made obsolete because it has been split. To update annotations, consider biological_process terms 'negative regulation of actin filament depolymerization ; GO:0030835' or its children and 'negative regulation of actin filament polymerization ; GO:0030837' or its children." to "This term was made obsolete because it has been split."
* Changed comment from "This term was made obsolete because it has been split. To update annotations, consider biological_process terms 'positive regulation of actin filament depolymerization ; GO:0030836' or its children and 'positive regulation of actin filament polymerization ; GO:0030838'." to "This term was made obsolete because it has been split."
* Changed comment from "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). To update annotations, consider biological_process term 'cellular calcium ion homeostasis ; GO:0006874' or its children and cellular_component term 'endoplasmic reticulum ; GO:0005783' or its children." to "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport')."
* Changed comment from "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport'). To update annotations, consider biological_process term 'cellular calcium ion homeostasis ; GO:0006874' or its children and cellular_component term 'endoplasmic reticulum ; GO:0005783' or its children." to "This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport')."
* Changed comment from "This term was made obsolete because cytoskeleton is not a process, so the term made no sense. To update annotations, consider biological_process term 'cytoskeleton organization and biogenesis ; GO:0007010' or its children." to "This term was made obsolete because cytoskeleton is not a process, so the term made no sense."
* Changed comment from "This term was made obsolete because cytoskeleton is not a process, so the term made no sense. To update annotations, consider biological_process term 'cytoskeleton organization and biogenesis ; GO:0007010' or its children." to "This term was made obsolete because cytoskeleton is not a process, so the term made no sense."
* Changed comment from "This term was made obsolete because it has been split. To update annotations, consider biological_process terms 'negative regulation of intermediate filament depolymerization ; GO:0030843' and 'negative regulation of intermediate filament polymerization ; GO:0030840'." to "This term was made obsolete because it has been split."
* Changed comment from "This term was made obsolete because it has been split. To update annotations, consider biological_process terms 'positive regulation of intermediate filament depolymerization ; GO:0030844' and 'positive regulation of intermediate filament polymerization ; GO:0030841'." to "This term was made obsolete because it has been split."
* Changed comment from "This term was made obsolete because it describes a substrate-specific process. To update annotations, use biological_process term 'regulation of mitotic recombination ; GO:0000019'." to "This term was made obsolete because it describes a substrate-specific process."
* Changed comment from "This term was made obsolete because it describes a substrate-specific process. To update annotations, consider biological_process term 'positive regulation of mitotic recombination ; GO:0045951'." to "This term was made obsolete because it describes a substrate-specific process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it relates to a specific gene family rather than a process. To update annotations, consider biological_process terms 'chromatin silencing ; GO:0006342' or its children and 'chromatin-mediated maintenance of transcription ; GO:0048096'." to "This term was made obsolete because it relates to a specific gene family rather than a process."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'coenzyme biosynthetic process ; GO:0009108' or its children and 'prosthetic group biosynthetic process ; GO:0051191'." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'coenzyme catabolic process ; GO:0009109' or its children and 'prosthetic group catabolic process ; GO:0051190'." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'negative regulation of coenzyme metabolic process ; GO:0051198' and 'negative regulation of prosthetic group metabolic process ; GO:0051201'." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because it was replaced by more specific terms. To update annotations, consider biological_process terms 'positive regulation of coenzyme metabolic process ; GO:0051197' and 'positive regulation of prosthetic group metabolic process ; GO:0051200'." to "This term was made obsolete because it was replaced by more specific terms."
* Changed comment from "This term was made obsolete because pentachlorophenol is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'pentachlorophenol metabolic process ; GO:0018961'." to "This term was made obsolete because pentachlorophenol is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '4-nitrophenol metabolic process ; GO:0018960'." to "This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because cresol is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'cresol metabolic process ; GO:0042212'." to "This term was made obsolete because cresol is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because m-cresol is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'm-cresol metabolic process ; GO:0018925'." to "This term was made obsolete because m-cresol is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because methyl ethyl ketone is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'methyl ethyl ketone metabolic process ; GO:0018928'." to "This term was made obsolete because methyl ethyl ketone is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2,4,5-trichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '2,4,5-trichlorophenoxyacetic acid metabolic process ; GO:0018980'." to "This term was made obsolete because 2,4,5-trichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '2-aminobenzenesulfonate metabolic process ; GO:0018868'." to "This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because carbazole is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'carbazole metabolic process ; GO:0018884'." to "This term was made obsolete because carbazole is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '3-hydroxyphenylacetate metabolic process ; GO:0019609'." to "This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because fluorene is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'fluorene metabolic process ; GO:0018917'." to "This term was made obsolete because fluorene is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because phenanthrene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'phenanthrene metabolic process ; GO:0018955'." to "This term was made obsolete because phenanthrene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because phthalates are not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'phthalate metabolic process ; GO:0018963'." to "This term was made obsolete because phthalates are not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because xylene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'xylene metabolic process ; GO:0018948'." to "This term was made obsolete because xylene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because m-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'm-xylene metabolic process ; GO:0018949'." to "This term was made obsolete because m-xylene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because o-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'o-xylene metabolic process ; GO:0018950'." to "This term was made obsolete because o-xylene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'p-xylene metabolic process ; GO:0018951'." to "This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because styrene is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term 'styrene metabolic process ; GO:0018966'." to "This term was made obsolete because styrene is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because toluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'toluene metabolic process ; GO:0018970'." to "This term was made obsolete because toluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because toluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'anaerobic toluene metabolic process ; GO:0018971'." to "This term was made obsolete because toluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '2,4,6-trinitrotoluene metabolic process ; GO:0018974'." to "This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'anaerobic 2,4,6-trinitrotoluene metabolic process ; GO:0018975'." to "This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'trinitrotoluene metabolic process ; GO:0018973'." to "This term was made obsolete because trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 4-nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '4-nitrotoluene metabolic process ; GO:0019257'." to "This term was made obsolete because 4-nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'nitrotoluene metabolic process ; GO:0019326'." to "This term was made obsolete because nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because thiocyanates are not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'thiocyanate metabolic process ; GO:0018969'." to "This term was made obsolete because thiocyanates are not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because triethanolamine is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'triethanolamine metabolic process ; GO:0018981'." to "This term was made obsolete because triethanolamine is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because toluene-4-sulfonate is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term 'toluene-4-sulfonate metabolic process ; GO:0018972'." to "This term was made obsolete because toluene-4-sulfonate is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 4-toluenecarboxylate is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '4-toluenecarboxylate metabolic process ; GO:0019611'." to "This term was made obsolete because 4-toluenecarboxylate is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 6-hydroxycineole is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '6-hydroxycineole metabolic process ; GO:0019638'." to "This term was made obsolete because 6-hydroxycineole is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2,4-dichlorobenzoate is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '2,4-dichlorobenzoate metabolic process ; GO:0018898'." to "This term was made obsolete because 2,4-dichlorobenzoate is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '2,4-dichlorophenoxyacetic acid metabolic process ; GO:0018901'." to "This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2-chloro-N-isopropylacetanilide is not synthesized by living organisms and GO does not cover non-biological processes. To update annotations, use biological_process term '2-chloro-N-isopropylacetanilide metabolic process ; GO:0018889'." to "This term was made obsolete because 2-chloro-N-isopropylacetanilide is not synthesized by living organisms and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because 2-nitropropane is not synthesized by living organisms, and GO does not cover non-biological processes. To update annotations, use biological_process term '2-nitropropane metabolic process ; GO:0018938'." to "This term was made obsolete because 2-nitropropane is not synthesized by living organisms, and GO does not cover non-biological processes."
* Changed comment from "This term was made obsolete because it is a gene product based term and it does not involve a unique process. To update annotations, consider biological_process term 'peptide transport ; GO:0015833' or its children." to "This term was made obsolete because it is a gene product based term and it does not involve a unique process."
* Changed comment from "This term was made obsolete because there is no evidence that this process is unique to Saccharomyces. To update annotations, use biological_process term 're-entry into mitotic cell cycle after pheromone arrest ; GO:0000321'." to "This term was made obsolete because there is no evidence that this process is unique to Saccharomyces."
* Changed comment from "This term was made obsolete because it does not describe a biological process. To update annotations, consider biological_process terms 'age-dependent general metabolic decline ; GO:0007571' or its children and 'nucleolar fragmentation ; GO:0007576' or its children." to "This term was made obsolete because it does not describe a biological process."
* Changed comment from "This term was made obsolete because a more appropriate term was created. To update annotations, use biological_process term 'ion homeostasis ; GO:0050801'." to "This term was made obsolete because a more appropriate term was created."
* Changed comment from "This term was made obsolete because there is no lysine at position 24 of histone H3. To update annotations, consider molecular_function term 'histone lysine N-methyltransferase activity (H3-K4 specific) ; GO:0042800'." to "This term was made obsolete because there is no lysine at position 24 of histone H3."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'peptide stabilization ; GO:0050822'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it represents a biological process. To update annotations, use biological_process term 'peptide antigen stabilization ; GO:0050823'." to "This term was made obsolete because it represents a biological process."
* Changed comment from "This term was made obsolete because it violates the principle of positivity. To update annotations, use biological_process term 'vesicle docking ; GO:0048278'." to "This term was made obsolete because it violates the principle of positivity."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process term 'trichome patterning ; GO:0048629'." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because more appropriate terms were created. To update annotations, consider biological_process term 'trichome patterning ; GO:0048629'." to "This term was made obsolete because more appropriate terms were created."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond ; GO:0046992' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it was an unnecessary grouping term. To update annotations, consider molecular_function term 'oxidoreductase activity, acting on phosphorus or arsenic in donors ; GO:0030613' or its children." to "This term was made obsolete because it was an unnecessary grouping term."
* Changed comment from "This term was made obsolete because it represents both process and function information. To update annotations, use biological_process term 'transport ; GO:0006810' and molecular_function term 'GTPase activity ; GO:0003924'." to "This term was made obsolete because it represents both process and function information."
* Changed name of GO:0050878 from "regulation of body fluids" to "regulation of body fluid levels"
* Added definition dbxref GOC:dph to GO:0050878
* Added definition dbxref GOC:tb to GO:0050878
* Copied GO:0050878 to GO:0065008 with type OBO_REL:is_a
* Changed definition of GO:0050891 from "Any process that modulates the osmotic activity of the fluid in a tissue, organ or organism." to "Any process that modulates the osmotic activity of the fluid in a tissue, organ or a multicellular organism."
* Added definition dbxref GOC:tb to GO:0050891
* Changed comment from "This term was made obsolete because it represents a process. To update annotations, use biological_process term 'protein tetramerization ; GO:0051262'." to "This term was made obsolete because it represents a process."
* Changed synonym scope of GO:0051091 from "Narrow" to "Exact"
* Changed name of GO:0051129 from "negative regulation of cell organization and biogenesis" to "negative regulation of cellular component organization and biogenesis"
* Changed name of GO:0051130 from "positive regulation of cell organization and biogenesis" to "positive regulation of cellular component organization and biogenesis"
* Changed name of GO:0051927 from "negative regulation of calcium ion transport via voltage gated calcium channel" to "negative regulation of calcium ion transport via voltage-gated calcium channel"
* Changed name of GO:0051929 from "positive regulation of calcium ion transport via voltage gated calcium channel" to "positive regulation of calcium ion transport via voltage-gated calcium channel"
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