[Go-diff] GO update 02/16/2009

Remote CVS for Gene Ontology gocvs at genome.stanford.edu
Mon Feb 16 21:30:49 PST 2009 

OBODIFF of gene_ontology_write.obo version 1.443 by 1.444

Starting obodiff at /share/go/bin/oboedit/current using 256M of memory
* Created object of type obo:TERM with id GO:0070358
* Created object of type obo:TERM with id GO:0070359
* Created object of type obo:TERM with id GO:0070360
* Created object of type obo:TERM with id GO:0070361
* Created object of type obo:TERM with id GO:0070362
* Created object of type obo:TERM with id GO:0070363
* Created object of type obo:TERM with id GO:0070364
* Created object of type obo:TERM with id GO:0070365
* Created object of type obo:TERM with id GO:0070366
* Created object of type obo:TERM with id GO:0070367
* Created object of type obo:TERM with id GO:0070368
* Created object of type obo:TERM with id GO:0070369
* Created object of type obo:TERM with id GO:0070370
* Created object of type obo:TERM with id GO:0070371
* Created object of type obo:TERM with id GO:0070372
* Created object of type obo:TERM with id GO:0070373
* Created object of type obo:TERM with id GO:0070374
* Created object of type obo:TERM with id GO:0070375
* Created object of type obo:TERM with id GO:0070376
* Created object of type obo:TERM with id GO:0070377
* Created object of type obo:TERM with id GO:0070378
* Created object of type obo:TERM with id GO:0070379
* Created object of type obo:TERM with id GO:0070380
* Populated new object GO:0070358 (macro)
  * Changed name of GO:0070358 from "<new term>" to "actin polymerization-dependent cell motility"
  * Set definition of GO:0070358 to "A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell."
  * Added definition dbxref GOC:mah to GO:0070358
  * Added definition dbxref PMID:15773977 to GO:0070358
  * Added GO:0070358 to category gosubset_prok
  * Added synonym "cell motility by actin tail formation" to GO:0070358
  * Added general dbxref PMID:15773977 to synonym cell motility by actin tail formation of GO:0070358
  * Changed synonym scope of GO:0070358 from "Related" to "Exact"
  * Copied GO:0070358 to GO:0048870 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070358
* Populated new object GO:0070359 (macro)
  * Changed name of GO:0070359 from "<new term>" to "actin polymerization-dependent cell motility involved in migration of symbiont within host"
  * Set definition of GO:0070359 to "A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell."
  * Added definition dbxref GOC:jl to GO:0070359
  * Added definition dbxref GOC:mah to GO:0070359
  * Added definition dbxref PMID:15773977 to GO:0070359
  * Added GO:0070359 to category gosubset_prok
  * Copied GO:0070359 to GO:0070360 with type part_of
  * Copied GO:0070359 to GO:0070358 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070359
* Populated new object GO:0070360 (macro)
  * Changed name of GO:0070360 from "<new term>" to "migration of symbiont within host by polymerization of host actin"
  * Set definition of GO:0070360 to "The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction."
  * Added definition dbxref GOC:jl to GO:0070360
  * Added definition dbxref GOC:mah to GO:0070360
  * Added GO:0070360 to category gosubset_prok
  * Copied GO:0070360 to GO:0044001 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070360
* Populated new object GO:0070361 (macro)
  * Changed name of GO:0070361 from "<new term>" to "mitochondrial light strand promoter anti-sense binding"
  * Set definition of GO:0070361 to "Interacting selectively with the anti-sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA."
  * Added definition dbxref GOC:mah to GO:0070361
  * Added definition dbxref PMID:9485316 to GO:0070361
  * Added synonym "LSP non-coding strand binding" to GO:0070361
  * Added general dbxref PMID:9485316 to synonym LSP non-coding strand binding of GO:0070361
  * Changed synonym scope of GO:0070361 from "Related" to "Exact"
  * Added synonym "LSPas binding" to GO:0070361
  * Added general dbxref PMID:9485316 to synonym LSPas binding of GO:0070361
  * Changed synonym scope of GO:0070361 from "Related" to "Exact"
  * Copied GO:0070361 to GO:0010843 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070361
* Populated new object GO:0070362 (macro)
  * Changed name of GO:0070362 from "<new term>" to "mitochondrial heavy strand promoter anti-sense binding"
  * Set definition of GO:0070362 to "Interacting selectively with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA."
  * Added definition dbxref GOC:mah to GO:0070362
  * Added definition dbxref PMID:9485316 to GO:0070362
  * Added synonym "HSP non-coding strand binding" to GO:0070362
  * Added general dbxref PMID:9485316 to synonym HSP non-coding strand binding of GO:0070362
  * Changed synonym scope of GO:0070362 from "Related" to "Exact"
  * Added synonym "HSPas binding" to GO:0070362
  * Added general dbxref PMID:9485316 to synonym HSPas binding of GO:0070362
  * Changed synonym scope of GO:0070362 from "Related" to "Exact"
  * Copied GO:0070362 to GO:0010843 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070362
* Populated new object GO:0070363 (macro)
  * Changed name of GO:0070363 from "<new term>" to "mitochondrial light strand promoter sense binding"
  * Set definition of GO:0070363 to "Interacting selectively with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA."
  * Added definition dbxref GOC:mah to GO:0070363
  * Added definition dbxref PMID:9485316 to GO:0070363
  * Added synonym "LSP coding strand binding" to GO:0070363
  * Added general dbxref PMID:9485316 to synonym LSP coding strand binding of GO:0070363
  * Changed synonym scope of GO:0070363 from "Related" to "Exact"
  * Added synonym "LSPs binding" to GO:0070363
  * Added general dbxref PMID:9485316 to synonym LSPs binding of GO:0070363
  * Changed synonym scope of GO:0070363 from "Related" to "Exact"
  * Copied GO:0070363 to GO:0010843 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070363
* Populated new object GO:0070364 (macro)
  * Changed name of GO:0070364 from "<new term>" to "mitochondrial heavy strand promoter sense binding"
  * Set definition of GO:0070364 to "Interacting selectively with the sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA."
  * Added definition dbxref GOC:mah to GO:0070364
  * Added definition dbxref PMID:9485316 to GO:0070364
  * Added synonym "HSP coding strand binding" to GO:0070364
  * Added general dbxref PMID:9485316 to synonym HSP coding strand binding of GO:0070364
  * Changed synonym scope of GO:0070364 from "Related" to "Exact"
  * Added synonym "HSPs binding" to GO:0070364
  * Added general dbxref PMID:9485316 to synonym HSPs binding of GO:0070364
  * Changed synonym scope of GO:0070364 from "Related" to "Exact"
  * Copied GO:0070364 to GO:0010843 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070364
* Populated new object GO:0070365 (macro)
  * Changed name of GO:0070365 from "<new term>" to "hepatocyte differentiation"
  * Set definition of GO:0070365 to "The process whereby a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver."
  * Added definition dbxref CL:0000182 to GO:0070365
  * Added definition dbxref PMID:7588884 to GO:0070365
  * Added synonym "liver cell differentiation" to GO:0070365
  * Added general dbxref GOC:mah to synonym liver cell differentiation of GO:0070365
  * Changed synonym scope of GO:0070365 from "Related" to "Exact"
  * Copied GO:0070365 to GO:0030154 with type OBO_REL:is_a
  * Copied GO:0070365 to GO:0001889 with type part_of
  * Assigned namespace "biological_process" to GO:0070365
* Populated new object GO:0070366 (macro)
  * Changed name of GO:0070366 from "<new term>" to "regulation of hepatocyte differentiation"
  * Set definition of GO:0070366 to "Any process that modulates the frequency, rate or extent of hepatocyte differentiation."
  * Added definition dbxref GOC:mah to GO:0070366
  * Added definition dbxref GOC:sl to GO:0070366
  * Added synonym "regulation of liver cell differentiation" to GO:0070366
  * Added general dbxref GOC:sl to synonym regulation of liver cell differentiation of GO:0070366
  * Changed synonym scope of GO:0070366 from "Related" to "Exact"
  * Copied GO:0070366 to GO:0045595 with type OBO_REL:is_a
  * Copied GO:0070366 to GO:0070365 with type regulates
  * Assigned namespace "biological_process" to GO:0070366
* Populated new object GO:0070367 (macro)
  * Changed name of GO:0070367 from "<new term>" to "negative regulation of hepatocyte differentiation"
  * Set definition of GO:0070367 to "Any process that stops or decreases the rate or extent of hepatocyte differentiation."
  * Added definition dbxref GOC:mah to GO:0070367
  * Added definition dbxref GOC:sl to GO:0070367
  * Added synonym "down regulation of hepatocyte differentiation" to GO:0070367
  * Added general dbxref GOC:mah to synonym down regulation of hepatocyte differentiation of GO:0070367
  * Changed synonym scope of GO:0070367 from "Related" to "Exact"
  * Added synonym "down-regulation of hepatocyte differentiation" to GO:0070367
  * Added general dbxref GOC:mah to synonym down-regulation of hepatocyte differentiation of GO:0070367
  * Changed synonym scope of GO:0070367 from "Related" to "Exact"
  * Added synonym "downregulation of hepatocyte differentiation" to GO:0070367
  * Added general dbxref GOC:mah to synonym downregulation of hepatocyte differentiation of GO:0070367
  * Changed synonym scope of GO:0070367 from "Related" to "Exact"
  * Added synonym "inhibition of hepatocyte differentiation" to GO:0070367
  * Added general dbxref GOC:mah to synonym inhibition of hepatocyte differentiation of GO:0070367
  * Changed synonym scope of GO:0070367 from "Related" to "Narrow"
  * Added synonym "negative regulation of liver cell differentiation" to GO:0070367
  * Added general dbxref GOC:sl<new dbxref> to synonym negative regulation of liver cell differentiation of GO:0070367
  * Changed synonym scope of GO:0070367 from "Related" to "Exact"
  * Copied GO:0070367 to GO:0045596 with type OBO_REL:is_a
  * Copied GO:0070367 to GO:0070365 with type negatively_regulates
  * Copied GO:0070367 to GO:0070366 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070367
* Populated new object GO:0070368 (macro)
  * Changed name of GO:0070368 from "<new term>" to "positive regulation of hepatocyte differentiation"
  * Set definition of GO:0070368 to "Any process that activates or increases the rate or extent of hepatocyte differentiation."
  * Added definition dbxref GOC:mah to GO:0070368
  * Added definition dbxref GOC:sl to GO:0070368
  * Added synonym "activation of hepatocyte differentiation" to GO:0070368
  * Added general dbxref GOC:mah to synonym activation of hepatocyte differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Narrow"
  * Added synonym "positive regulation of liver cell differentiation" to GO:0070368
  * Added general dbxref GOC:sl to synonym positive regulation of liver cell differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Exact"
  * Added synonym "stimulation of hepatocyte differentiation" to GO:0070368
  * Added general dbxref GOC:mah to synonym stimulation of hepatocyte differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Narrow"
  * Added synonym "up regulation of hepatocyte differentiation" to GO:0070368
  * Added general dbxref GOC:mah to synonym up regulation of hepatocyte differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Exact"
  * Added synonym "up-regulation of hepatocyte differentiation" to GO:0070368
  * Added general dbxref GOC:mah to synonym up-regulation of hepatocyte differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Exact"
  * Added synonym "upregulation of hepatocyte differentiation" to GO:0070368
  * Added general dbxref GOC:mah to synonym upregulation of hepatocyte differentiation of GO:0070368
  * Changed synonym scope of GO:0070368 from "Related" to "Exact"
  * Copied GO:0070368 to GO:0070366 with type OBO_REL:is_a
  * Copied GO:0070368 to GO:0045597 with type OBO_REL:is_a
  * Copied GO:0070368 to GO:0070365 with type positively_regulates
  * Assigned namespace "biological_process" to GO:0070368
* Populated new object GO:0070369 (macro)
  * Changed name of GO:0070369 from "<new term>" to "beta-catenin-TCF7L2 complex"
  * Set definition of GO:0070369 to "A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription."
  * Added definition dbxref GOC:rl to GO:0070369
  * Added definition dbxref PMID:9065401 to GO:0070369
  * Added definition dbxref PMID:9065402 to GO:0070369
  * Added GO:0070369 to category gosubset_prok
  * Added synonym "beta-catenin-TCF4 complex" to GO:0070369
  * Added general dbxref PMID:9065401 to synonym beta-catenin-TCF4 complex of GO:0070369
  * Added general dbxref PMID:9065402 to synonym beta-catenin-TCF4 complex of GO:0070369
  * Changed synonym scope of GO:0070369 from "Related" to "Exact"
  * Copied GO:0070369 to GO:0044445 with type OBO_REL:is_a
  * Copied GO:0070369 to GO:0043234 with type OBO_REL:is_a
  * Assigned namespace "cellular_component" to GO:0070369
* Populated new object GO:0070370 (macro)
  * Changed name of GO:0070370 from "<new term>" to "cellular heat acclimation"
  * Set definition of GO:0070370 to "Any process that increases heat tolerance of a cell in response to high temperatures."
  * Added definition dbxref GOC:jp to GO:0070370
  * Added synonym "cellular thermotolerance" to GO:0070370
  * Added general dbxref GOC:jp to synonym cellular thermotolerance of GO:0070370
  * Changed synonym scope of GO:0070370 from "Related" to "Exact"
  * Copied GO:0070370 to GO:0034605 with type OBO_REL:is_a
  * Copied GO:0070370 to GO:0010286 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070370
* Populated new object GO:0070371 (macro)
  * Changed name of GO:0070371 from "<new term>" to "ERK1 and ERK2 cascade"
  * Added comment "Note that this MAPKKK cascade is commonly refered to as the ERK pathway in the literature, but involves only ERK1 or ERK2, not other ERK kinases."
  * Set definition of GO:0070371 to "A cascade of protein kinase activities, culminating in the phosphorylation and activation of either the ERK1 or ERK2 kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases."
  * Added definition dbxref GOC:add to GO:0070371
  * Added definition dbxref ISBN:0121245462 to GO:0070371
  * Added definition dbxref ISBN:0896039986 to GO:0070371
  * Added synonym "ERK cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym ERK cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Broad"
  * Added synonym "ERK1 and ERK2 signaling pathway" to GO:0070371
  * Added general dbxref GOC:mah to synonym ERK1 and ERK2 signaling pathway of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Exact"
  * Added synonym "ERK1 and ERK2 signalling pathway" to GO:0070371
  * Added general dbxref GOC:mah to synonym ERK1 and ERK2 signalling pathway of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Exact"
  * Added synonym "ERK1 cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym ERK1 cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Narrow"
  * Added synonym "ERK1/2 cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym ERK1/2 cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Exact"
  * Added synonym "ERK2 cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym ERK2 cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Narrow"
  * Added synonym "MAPK1 cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym MAPK1 cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Narrow"
  * Added synonym "MAPK3 cascade" to GO:0070371
  * Added general dbxref GOC:add to synonym MAPK3 cascade of GO:0070371
  * Changed synonym scope of GO:0070371 from "Related" to "Narrow"
  * Copied GO:0070371 to GO:0000165 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070371
* Populated new object GO:0070372 (macro)
  * Changed name of GO:0070372 from "<new term>" to "regulation of ERK1 and ERK2 cascade"
  * Set definition of GO:0070372 to "Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."
  * Added definition dbxref GOC:add to GO:0070372
  * Added definition dbxref ISBN:0121245462 to GO:0070372
  * Added definition dbxref ISBN:0896039986 to GO:0070372
  * Added synonym "regulation of ERK cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of ERK cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Broad"
  * Added synonym "regulation of ERK1 and ERK2 signaling pathway" to GO:0070372
  * Added general dbxref GOC:mah to synonym regulation of ERK1 and ERK2 signaling pathway of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Exact"
  * Added synonym "regulation of ERK1 and ERK2 signalling pathway" to GO:0070372
  * Added general dbxref GOC:mah to synonym regulation of ERK1 and ERK2 signalling pathway of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Exact"
  * Added synonym "regulation of ERK1 cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of ERK1 cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Narrow"
  * Added synonym "regulation of ERK1/2 cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of ERK1/2 cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Exact"
  * Added synonym "regulation of ERK2 cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of ERK2 cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Narrow"
  * Added synonym "regulation of MAPK1 cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of MAPK1 cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Narrow"
  * Added synonym "regulation of MAPK3 cascade" to GO:0070372
  * Added general dbxref GOC:add to synonym regulation of MAPK3 cascade of GO:0070372
  * Changed synonym scope of GO:0070372 from "Related" to "Narrow"
  * Copied GO:0070372 to GO:0043408 with type OBO_REL:is_a
  * Copied GO:0070372 to GO:0070371 with type regulates
  * Assigned namespace "biological_process" to GO:0070372
* Populated new object GO:0070373 (macro)
  * Changed name of GO:0070373 from "<new term>" to "negative regulation of ERK1 and ERK2 cascade"
  * Set definition of GO:0070373 to "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."
  * Added definition dbxref GOC:add to GO:0070373
  * Added definition dbxref ISBN:0121245462 to GO:0070373
  * Added definition dbxref ISBN:0896039986 to GO:0070373
  * Added synonym "down regulation of ERK1 and ERK2 cascade" to GO:0070373
  * Added general dbxref GOC:mah to synonym down regulation of ERK1 and ERK2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "down-regulation of ERK1 and ERK2 cascade" to GO:0070373
  * Added general dbxref GOC:mah to synonym down-regulation of ERK1 and ERK2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "downregulation of ERK1 and ERK2 cascade" to GO:0070373
  * Added general dbxref GOC:mah to synonym downregulation of ERK1 and ERK2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "inhibition of ERK1 and ERK2 cascade" to GO:0070373
  * Added general dbxref GOC:mah to synonym inhibition of ERK1 and ERK2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Narrow"
  * Added synonym "negative regulation of ERK cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of ERK cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Broad"
  * Added synonym "negative regulation of ERK1 and ERK2 signaling pathway" to GO:0070373
  * Added general dbxref GOC:mah to synonym negative regulation of ERK1 and ERK2 signaling pathway of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "negative regulation of ERK1 and ERK2 signalling pathway" to GO:0070373
  * Added general dbxref GOC:mah to synonym negative regulation of ERK1 and ERK2 signalling pathway of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "negative regulation of ERK1 cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of ERK1 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Narrow"
  * Added synonym "negative regulation of ERK1/2 cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of ERK1/2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Exact"
  * Added synonym "negative regulation of ERK2 cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of ERK2 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Narrow"
  * Added synonym "negative regulation of MAPK1 cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of MAPK1 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Narrow"
  * Added synonym "negative regulation of MAPK3 cascade" to GO:0070373
  * Added general dbxref GOC:add to synonym negative regulation of MAPK3 cascade of GO:0070373
  * Changed synonym scope of GO:0070373 from "Related" to "Narrow"
  * Copied GO:0070373 to GO:0070371 with type negatively_regulates
  * Copied GO:0070373 to GO:0070372 with type OBO_REL:is_a
  * Copied GO:0070373 to GO:0043409 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070373
* Populated new object GO:0070374 (macro)
  * Changed name of GO:0070374 from "<new term>" to "positive regulation of ERK1 and ERK2 cascade"
  * Set definition of GO:0070374 to "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade."
  * Added definition dbxref GOC:mah to GO:0070374
  * Added synonym "activation of ERK1 and ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:mah to synonym activation of ERK1 and ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "positive regulation of ERK cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of ERK cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Broad"
  * Added synonym "positive regulation of ERK1 and ERK2 signaling pathway" to GO:0070374
  * Added general dbxref GOC:mah to synonym positive regulation of ERK1 and ERK2 signaling pathway of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Added synonym "positive regulation of ERK1 and ERK2 signalling pathway" to GO:0070374
  * Added general dbxref GOC:mah to synonym positive regulation of ERK1 and ERK2 signalling pathway of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Added synonym "positive regulation of ERK1 cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of ERK1 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "positive regulation of ERK1/2 cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of ERK1/2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Added synonym "positive regulation of ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "positive regulation of MAPK1 cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of MAPK1 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "positive regulation of MAPK3 cascade" to GO:0070374
  * Added general dbxref GOC:add to synonym positive regulation of MAPK3 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "stimulation of ERK1 and ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:mah to synonym stimulation of ERK1 and ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Narrow"
  * Added synonym "up regulation of ERK1 and ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:mah to synonym up regulation of ERK1 and ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Added synonym "up-regulation of ERK1 and ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:mah to synonym up-regulation of ERK1 and ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Added synonym "upregulation of ERK1 and ERK2 cascade" to GO:0070374
  * Added general dbxref GOC:mah to synonym upregulation of ERK1 and ERK2 cascade of GO:0070374
  * Changed synonym scope of GO:0070374 from "Related" to "Exact"
  * Copied GO:0070374 to GO:0043410 with type OBO_REL:is_a
  * Copied GO:0070374 to GO:0070372 with type OBO_REL:is_a
  * Copied GO:0070374 to GO:0070371 with type positively_regulates
  * Assigned namespace "biological_process" to GO:0070374
* Populated new object GO:0070375 (macro)
  * Changed name of GO:0070375 from "<new term>" to "BMK cascade"
  * Set definition of GO:0070375 to "A cascade of protein kinase activities, culminating in the phosphorylation and activation of big MAP kinase (BMK1/ERK5), which is a type of mitogen-activated protein (MAP) kinases."
  * Added definition dbxref GOC:add to GO:0070375
  * Added definition dbxref ISBN:0896039986 to GO:0070375
  * Added definition dbxref PMID:16376520 to GO:0070375
  * Added definition dbxref PMID:16880823 to GO:0070375
  * Added synonym "BMK signaling pathway" to GO:0070375
  * Added general dbxref GOC:mah to synonym BMK signaling pathway of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Added synonym "BMK signalling pathway" to GO:0070375
  * Added general dbxref GOC:mah to synonym BMK signalling pathway of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Added synonym "BMK1 cascade" to GO:0070375
  * Added general dbxref GOC:add to synonym BMK1 cascade of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Added synonym "ERK5 cascade" to GO:0070375
  * Added general dbxref GOC:add to synonym ERK5 cascade of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Added synonym "ERK5 signaling pathway" to GO:0070375
  * Added general dbxref PMID:16376520 to synonym ERK5 signaling pathway of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Added synonym "MAPK7 cascade" to GO:0070375
  * Added general dbxref GOC:add to synonym MAPK7 cascade of GO:0070375
  * Changed synonym scope of GO:0070375 from "Related" to "Exact"
  * Copied GO:0070375 to GO:0000165 with type OBO_REL:is_a
  * Assigned namespace "biological_process" to GO:0070375
* Populated new object GO:0070376 (macro)
  * Changed name of GO:0070376 from "<new term>" to "regulation of BMK cascade"
  * Set definition of GO:0070376 to "Any process that modulates the frequency, rate or extent of signal transduction mediated by the BMK cascade."
  * Added definition dbxref GOC:add to GO:0070376
  * Added definition dbxref ISBN:0121245462 to GO:0070376
  * Added definition dbxref ISBN:0896039986 to GO:0070376
  * Added synonym "regulation of BMK signaling pathway" to GO:0070376
  * Added general dbxref GOC:mah to synonym regulation of BMK signaling pathway of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Added synonym "regulation of BMK signalling pathway" to GO:0070376
  * Added general dbxref GOC:mah to synonym regulation of BMK signalling pathway of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Added synonym "regulation of BMK1 cascade" to GO:0070376
  * Added general dbxref GOC:add to synonym regulation of BMK1 cascade of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Added synonym "regulation of ERK5 cascade" to GO:0070376
  * Added general dbxref GOC:add to synonym regulation of ERK5 cascade of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Added synonym "regulation of ERK5 signaling pathway" to GO:0070376
  * Added general dbxref PMID:16376520 to synonym regulation of ERK5 signaling pathway of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Added synonym "regulation of MAPK7 cascade" to GO:0070376
  * Added general dbxref GOC:add to synonym regulation of MAPK7 cascade of GO:0070376
  * Changed synonym scope of GO:0070376 from "Related" to "Exact"
  * Copied GO:0070376 to GO:0043408 with type OBO_REL:is_a
  * Copied GO:0070376 to GO:0070375 with type regulates
  * Assigned namespace "biological_process" to GO:0070376
* Populated new object GO:0070377 (macro)
  * Changed name of GO:0070377 from "<new term>" to "negative regulation of BMK cascade"
  * Set definition of GO:0070377 to "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the BMK cascade."
  * Added definition dbxref GOC:add to GO:0070377
  * Added definition dbxref ISBN:0121245462 to GO:0070377
  * Added definition dbxref ISBN:0896039986 to GO:0070377
  * Added synonym "down regulation of BMK cascade" to GO:0070377
  * Added general dbxref GOC:mah to synonym down regulation of BMK cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "down-regulation of BMK cascade" to GO:0070377
  * Added general dbxref GOC:mah to synonym down-regulation of BMK cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "downregulation of BMK cascade" to GO:0070377
  * Added general dbxref GOC:mah to synonym downregulation of BMK cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "inhibition of BMK cascade" to GO:0070377
  * Added general dbxref GOC:mah to synonym inhibition of BMK cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Narrow"
  * Added synonym "negative regulation of BMK signaling pathway" to GO:0070377
  * Added general dbxref GOC:mah to synonym negative regulation of BMK signaling pathway of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "negative regulation of BMK signalling pathway" to GO:0070377
  * Added general dbxref GOC:mah to synonym negative regulation of BMK signalling pathway of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "negative regulation of BMK1 cascade" to GO:0070377
  * Added general dbxref GOC:add to synonym negative regulation of BMK1 cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "negative regulation of ERK5 cascade" to GO:0070377
  * Added general dbxref GOC:add to synonym negative regulation of ERK5 cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "negative regulation of ERK5 signaling pathway" to GO:0070377
  * Added general dbxref PMID:16376520 to synonym negative regulation of ERK5 signaling pathway of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Added synonym "negative regulation of MAPK7 cascade" to GO:0070377
  * Added general dbxref GOC:add to synonym negative regulation of MAPK7 cascade of GO:0070377
  * Changed synonym scope of GO:0070377 from "Related" to "Exact"
  * Copied GO:0070377 to GO:0070376 with type OBO_REL:is_a
  * Copied GO:0070377 to GO:0043409 with type OBO_REL:is_a
  * Copied GO:0070377 to GO:0070375 with type negatively_regulates
  * Assigned namespace "biological_process" to GO:0070377
* Populated new object GO:0070378 (macro)
  * Changed name of GO:0070378 from "<new term>" to "positive regulation of BMK cascade"
  * Set definition of GO:0070378 to "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the BMK cascade."
  * Added definition dbxref GOC:mah to GO:0070378
  * Added synonym "activation of BMK cascade" to GO:0070378
  * Added general dbxref GOC:mah to synonym activation of BMK cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Narrow"
  * Added synonym "positive regulation of BMK signaling pathway" to GO:0070378
  * Added general dbxref GOC:mah to synonym positive regulation of BMK signaling pathway of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "positive regulation of BMK signalling pathway" to GO:0070378
  * Added general dbxref GOC:mah to synonym positive regulation of BMK signalling pathway of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "positive regulation of BMK1 cascade" to GO:0070378
  * Added general dbxref GOC:add to synonym positive regulation of BMK1 cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "positive regulation of ERK5 cascade" to GO:0070378
  * Added general dbxref GOC:add to synonym positive regulation of ERK5 cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "positive regulation of ERK5 signaling pathway" to GO:0070378
  * Added general dbxref PMID:16376520 to synonym positive regulation of ERK5 signaling pathway of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "positive regulation of MAPK7 cascade" to GO:0070378
  * Added general dbxref GOC:add to synonym positive regulation of MAPK7 cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "stimulation of BMK cascade" to GO:0070378
  * Added general dbxref GOC:mah to synonym stimulation of BMK cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Narrow"
  * Added synonym "up regulation of BMK cascade" to GO:0070378
  * Added general dbxref GOC:mah to synonym up regulation of BMK cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "up-regulation of BMK cascade" to GO:0070378
  * Added general dbxref GOC:mah to synonym up-regulation of BMK cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Added synonym "upregulation of BMK cascade" to GO:0070378
  * Added general dbxref GOC:mah to synonym upregulation of BMK cascade of GO:0070378
  * Changed synonym scope of GO:0070378 from "Related" to "Exact"
  * Copied GO:0070378 to GO:0070376 with type OBO_REL:is_a
  * Copied GO:0070378 to GO:0043410 with type OBO_REL:is_a
  * Copied GO:0070378 to GO:0070375 with type positively_regulates
  * Assigned namespace "biological_process" to GO:0070378
* Populated new object GO:0070379 (macro)
  * Changed name of GO:0070379 from "<new term>" to "high mobility group box 1 binding"
  * Set definition of GO:0070379 to "Interacting selectively with high mobility group box 1 (HMBGB1)."
  * Added definition dbxref GOC:add to GO:0070379
  * Added definition dbxref PMID:18431461 to GO:0070379
  * Added synonym "HMGB1 binding" to GO:0070379
  * Added general dbxref GOC:add to synonym HMGB1 binding of GO:0070379
  * Changed synonym scope of GO:0070379 from "Related" to "Exact"
  * Copied GO:0070379 to GO:0019955 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070379
* Populated new object GO:0070380 (macro)
  * Changed name of GO:0070380 from "<new term>" to "high mobility group box 1 receptor activity"
  * Set definition of GO:0070380 to "Combining with high mobility group box 1 (HMBGB1) to initiate a change in cell activity."
  * Added definition dbxref GOC:add to GO:0070380
  * Added definition dbxref PMID:18431461 to GO:0070380
  * Added synonym "HMGB1 receptor activity" to GO:0070380
  * Added general dbxref GOC:add to synonym HMGB1 receptor activity of GO:0070380
  * Changed synonym scope of GO:0070380 from "Related" to "Exact"
  * Copied GO:0070380 to GO:0004896 with type OBO_REL:is_a
  * Copied GO:0070380 to GO:0070379 with type OBO_REL:is_a
  * Assigned namespace "molecular_function" to GO:0070380
* Added synonym "JNK1 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym JNK1 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "JNK2 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym JNK2 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "JNK3 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym JNK3 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "MAPK10 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym MAPK10 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "MAPK8 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym MAPK8 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "MAPK9 cascade" to GO:0007254
* Added general dbxref GOC:add to synonym MAPK9 cascade of GO:0007254
* Changed synonym scope of GO:0007254 from "Related" to "Narrow"
* Added synonym "MAPK11 cascade" to GO:0051403
* Added general dbxref GOC:add to synonym MAPK11 cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Narrow"
* Added synonym "MAPK12 cascade" to GO:0051403
* Added general dbxref GOC:add to synonym MAPK12 cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Narrow"
* Added synonym "MAPK13 cascade" to GO:0051403
* Added general dbxref GOC:add to synonym MAPK13 cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Narrow"
* Added synonym "MAPK14 cascade" to GO:0051403
* Added general dbxref GOC:add to synonym MAPK14 cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Narrow"
* Added synonym "p38 cascade" to GO:0051403
* Added general dbxref GOC:add to synonym p38 cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Narrow"
* Added synonym "SAPK cascade" to GO:0051403
* Added general dbxref GOC:add to synonym SAPK cascade of GO:0051403
* Changed synonym scope of GO:0051403 from "Related" to "Broad"

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