[go]

Jim Hu jimhu at tamu.edu
Thu Aug 9 08:16:57 PDT 2007


Is there an existing process term for RNA-mediated inhibition of  
translation as it works in prokaryotes?  There are many examples of  
small RNAs that bind around the translation start site to block  
initiation (often with the help of hfq) or promote RNA degradation.   
I'm seeing these annotated by others to
	GO:0016246 ! RNA interference,

but this strikes me as very wrong.  No dsRNA, and the processes are  
evolutionarily unrelated.

I'm not crazy about

	GO:0042868 ! antisense RNA metabolic process

for this either.  It also goes into the epigenetic path, which I  
don't think applies here.

Jim


=====================================
Jim Hu
Associate Professor
Dept. of Biochemistry and Biophysics
2128 TAMU
Texas A&M Univ.
College Station, TX 77843-2128
979-862-4054





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