[go] 'regulation of gene expression'

Pankaj Jaiswal pj37 at cornell.edu
Thu Aug 9 11:54:48 PDT 2007


I think here there are two aspects that being captured in terms of 
expression (transcription/translation processes) and regulation of 
expression. Former is the case whether the gene-x is participating in 
the transcription/translation process or the later one where it is 
simply participating/regulating the transcription/translation process 
that the gene-x would undergo.  Since regulation here always has a 
dependency of another gene (most likely not gene product), I prefer to 
see it more like a gene to gene interaction data and less of a 
biological process, because as Harold says often there is insufficient 
information to support say gene-x is involved in the process of gene-y. 
In Gramene we have a way to capture this aspect under gene interaction.

Pankaj

Harold Drabkin wrote:
> IMHO, no;
> Some "experiments" do not give real information other than to help you 
> design what experiments will.
> Again, I am signing off on this with grave reservations.
> 
> hjd
> 
> Pascale Gaudet wrote:
>> But isn't it already more information than annotating to the root term?
>>
>> Harold Drabkin wrote:
>>> Moi???
>>>
>>> Well; my feeling hasn't changed but everyone else thinks it's a 
>>> meaningful term. I like it a bit better than the " biosynthesis  of" 
>>> terms. I still feel it doesn't say much if you say gene product x is 
>>> involved in the regulation of gene expression  based on an 
>>> observation that doing something to x causes the levels of other gene 
>>> products to change, without knowing actually what is happening. Still 
>>> seems like to me like making a term to use for incomplete or 
>>> ill-defined experiments. Just my take.
>>>
>>> hjd
>>>
>>>
>>> Jane Lomax wrote:
>>>> Actually, I was just waiting for Harold's blessing on this item...
>>>>
>>>> Jane
>>>>
>>>> Midori Harris wrote:
>>>>> So did I! I think what happened is simply that the SF item is 
>>>>> assigned to Jane, and she's been so busy with various2go mappings 
>>>>> and advocacy stuff that she hasn't had a chance to work on her 
>>>>> other SF things.
>>>>>
>>>>> m
>>>>>
>>>>> On Mon, 6 Aug 2007, David Hill wrote:
>>>>>
>>>>>> I thought it was going to be implemented.
>>>>>>
>>>>>> David
>>>>>>
>>>>>> Karen Christie wrote:
>>>>>>> Hi Tanya,
>>>>>>>
>>>>>>> There seems to be a stalled SF item on this topic:
>>>>>>>
>>>>>>> [ 1418820 ] gene expression
>>>>>>> https://sourceforge.net/tracker/index.php?func=detail&aid=1418820&group_id=36855&atid=440764 
>>>>>>>
>>>>>>> -Karen
>>>>>>>
>>>>>>>
>>>>>>> On Mon, 6 Aug 2007, Tanya Berardini wrote:
>>>>>>>
>>>>>>>> A (long) while back, we'd talked about having a term for 
>>>>>>>> 'regulation of gene expression'.  I've been searching the email 
>>>>>>>> archives without much luck hoping to find out what happened with 
>>>>>>>> respect to that item.  The last I found was an action item from 
>>>>>>>> the Sept. 2002 (!) meeting.
>>>>>>>>
>>>>>>>> Collective memory, please help out!
>>>>>>>>
>>>>>>>> Thanks,
>>>>>>>>
>>>>>>>> Tanya
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>> ------------------------------------------------------------------------------------------ 
>>>>>>>> Tanya Berardini, Ph.D.            tberardi at acoma.stanford.edu
>>>>>>>> The Arabidopsis Information Resource    FAX: (650) 325-6857
>>>>>>>> Carnegie Institution of Washington    Tel: (650) 325-1521 ext. 325
>>>>>>>> Department of Plant Biology        URL: http://arabidopsis.org/
>>>>>>>> 260 Panama St.
>>>>>>>> Stanford, CA 94305
>>>>>>>>
>>>>>>>> ------------------------------------------------------------------------------------------ 
>>>>>>>>
>>>>>>
>>>>
>>>
>>>
>>
> 
> 

-- 
Pankaj Jaiswal
G-15, Bradfield Hall
Dept. of Plant Breeding and Genetics
Cornell University
Ithaca, NY-14853, USA

Ph. +1-607-255-3103 / 4199
fax: +1-607-255-6683



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