[go] Re: Fwd: GO and Reverse Engineering of Gene Regulatory Networks

[Kimberly Van Auken]

Hi--

This query came to the go-help mailing list this morning.

Is there anyone with expertise in reverse engineering of gene regulatory 
networks who would be
willing to comment?

Thanks,
Kimberly

> Date: Wed, 12 Dec 2007 07:35:50 -0800 (PST)
> Message-Id: <200712121535.HAA29053 at bread.Stanford.EDU 
> <mailto:200712121535.HAA29053 at bread.Stanford.EDU>>
> To: f.b.yavari at gmail.com <mailto:f.b.yavari at gmail.com>
> Subject: GO Help query (from website)
> From: noreply at genome.stanford.edu <mailto:noreply at genome.stanford.edu>
>
> contactName: Fatemeh
> contactEmail: f.b.yavari at gmail.com <mailto:f.b.yavari at gmail.com>
> contactText: I wonder if GO annotations are extracted from known 
> information about genes, I mean if we have GO information for a gene 
> doesn't it mean that we know its relationships with other gens, its 
> function, the pathways that it is included in and...? and so when we 
> have all these information about a gene, we can't use these 
> information in reverse engineering of gene regulatory networks,right? 
> I mean we shouldn't use GO information in modeling gene regultory 
> networks, because they are extracted from exactly what are searching 
> for, right?
> If GOs are used as input information and known biological knowledge 
> for reverse engineering of GRN, it is lik that we use a special input 
> to get it in output! Isn't it?
>
>