[go] offer of human GO annotations

Jennifer Deegan (nee Clark) jdeegan at ebi.ac.uk
Thu Nov 1 03:05:51 PDT 2007


Hi Susan,

Thanks, this is exactly the kind of information we are looking for. We 
will follow it up.

Jen

Susan Tweedie wrote:
> This is probably most relevant to Emily but others may like to comment.
> Also Jen's may like to include this in her 'feedback from conferences'
> aspect of the outreach report.
> 
> Kira Anthony from the PathwayInteractionDatabase  -
> http://pid.nci.nih.gov (a collaboration between th U.S. National Cancer
> Institute and Nature Publishing Group) talked to several of us at the
> biocurator meeting and expressed an interest in submitting their GO
> annotations relating to signalling pathways. The data is basically all
> human (in some cases they know there is evidence in other species but
> I'm not sure if they record the annotation details for the other
> species).
> 
> One problem with submitting their data is that they use a mix of GO
> evidence codes and their own codes. 
> 
> e.g. IOS (inferred from other species) i.e. no evidence in human; IAE
> (inferred from array experiments) chIP on chip, protein arrays, chemical
> compound arrays; IFC (inferred from functional complementation); RGE
> (inferred from reporter gene expression).
> 
> However, it looks like most of these would map onto GO codes.
> 
> Another point to clarify is whether they track which evidence is
> associated with which reference - this isn't obvious from the way they
> present it on the web but I haven't had more than a cursory look. 
> 
> Kira's email is k.anthony at boston.nature.com. I said I would pass on her
> offer to the consortium and we'd get back to her.
> 
> Thanks,
> 
> Susan
> 

-- 
Jennifer Deegan (nee Clark)
EMBL-European Bioinformatics Institute
Gene Ontology Consortium



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