[go] Putting method/program names into the with field for ISS
Benjamin Hitz
hitz at genome.Stanford.EDU
Tue Sep 11 10:05:54 PDT 2007
On Sep 11, 2007, at 7:55 AM, Gwinn-Giglio, Michelle wrote:
>
>
> Hi,
>
> I disagree. I think taking this approach would significantly muddy
> the waters in terms of distinguishing between ISS and RCA.
>
> Anything that is based only on sequence analysis, be it simple
> Blast or vastly more complicated modeling methods, should be ISS
> because at their heart they are all comparing sequences of known
> function to ones with unknown function. Whether they do simple
> alignments to make that comparison or more complicated models, it
> is still a sequence based analysis.
I did not suggest otherwise.
Ben
--
Ben Hitz
Senior Scientific Programmer ** Saccharomyces Genome Database ** GO
Consortium
Stanford University ** hitz at genome.stanford.edu
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