[Go] Gene Symbols as GO synonyms
Ruth Lovering
r.lovering at ucl.ac.uk
Thu Apr 3 04:29:01 PDT 2008
Hi Jen
when I first looked at GO I found it rather disconcerting to see gene
symbols listed as synonyms for the GO term, because I didn't
appreciate the [related] and [exact] concepts.
As the annotation of genes improves I do think that the use of
synonyms becomes redundant, as the option of looking at what genes are
associated with the term and provides the same information as the
synonym.
I guess that the ideal approach would be to make sure that any deleted
gene symbol synonyms are annotated with that GO term (if only - sorry
to say this - with a TAS statement). And that in future editors,
rather than add the gene symbol as a synonym, make this annotation
directly to the gene itself. (sorry bit radical)
If this was achieved then people could find terms they are interested
in by looking at the annotation of p53, and would see other
potentially relevant terms too.
Ruth
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