[Go] Alert: proposal to obsolete GO:0046410 that impacts existing annotations

Midori Harris midori at ebi.ac.uk
Wed Dec 17 06:47:59 PST 2008


Dear GO,

The proposal has been made to obsolete

    2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity ; GO:0046410

Annotations to GO:0046410 exist as listed below:

   	DB	total
 	goa_uniprot	28 (all IEA)
 	tigr_Lmonocytogenes	1 (ISS)

The reason for obsoleting this term is that it was derived from an EC
entry (2.5.1.64) that has since been split into two entries. Terms
suggested for annotation updates correspond to the two "replacement"
EC entries:

    2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
    synthase activity ; GO:0070204
  	(EC:2.2.1.9)
    2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
    ; GO:0070205
  	(EC:4.2.99.20)

This term is in the prokaryote subset, but not in any GO slims
maintained in the gene_ontology_write.obo file. It is also used in the
following external mappings:

ec2go:EC:2.5.1.64 > GO:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity ; GO:0046410

tigrfams2go:JCVI_TIGRFAMS:TIGR00173 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase > GO:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity ; GO:0046410

SourceForge link:
https://sourceforge.net/tracker/index.php?func=detail&aid=2431491&group_id=36855&atid=440764

Comment period ends on December 31, 2008.

*** Unless objections are received by December 31,
       we will assume that you agree to this change. ***

Thanks,
Midori


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