[go] evidence code ontology

Helen Parkinson parkinson at ebi.ac.uk
Wed Feb 6 01:58:00 PST 2008


On behalf of OBI we'd be very happy to have an interaction with ECO when 
you decide what is the appropriate time and format. OBI developers are 
still working towards a 1.0 release, and after that might be a good 
point in our development process to have this discussion. This is likely 
to be some time in the summer, though a pre 1.0 release will be 
available in March,

thanks

Helen

Sue Rhee wrote:
> Actually I don't agree with the ECO representing evidence types, 
> contrary to the name of the ontology and the term names. Perhaps the 
> 'inferred from' should probably be omitted from term names and the 
> ontology renamed as Evidence Source Ontology. In my view, it 
> represents types of methods that are used to generate results that are 
> used as evidences for an assertion. So eventually I see the leaf nodes 
> of this ontology being individual assay types. In this view, the ECO 
> could be considered as some sort of meta ontology for the OBI.
>
> Sue
>
> Suzanna Lewis wrote:
>> Chris said it much better than I.
>>
>> I agree fully with this summary.
>>
>> -S
>>
>> On Feb 5, 2008, at 4:01 PM, Chris Mungall wrote:
>>
>>>
>>> At the moment, ECO isn't very ontology-like. As Larry pointed out, 
>>> it's more of a terminology of codes with specific instructions on 
>>> what fields should be filled in the GAF. The adoption of ECO by 
>>> phenoscape and the extension to homology-based evidence types is a 
>>> good thing and should hopefully keep ECO general enough for use 
>>> outside GO. At the same time, ECO has to be guaranteed to fulfill 
>>> certain GO requirements.
>>>
>>> OBI is a massive and impressive effort - but it is still young. Its 
>>> emphasis is on representing actual experiments and associated 
>>> entities - rather than codes - which is a good thing. It is 
>>> certainly the OBO ontology for representing an experiment. But ECO 
>>> doesn't represent experiments per se - it represents evidence and/or 
>>> inference, which presents additional challenges.
>>>
>>> I would say the evidence group should be actively engaging OBI, we 
>>> should be trying to define ECO terms using OBI terms where possible. 
>>> Likewise the OBI group should treat ECO as a set of requirements. 
>>> And I think we can use OBI to provide a better structure to ECO. But 
>>> I think it is too soon to talk of immediately subsuming ECO into OBI 
>>> - sorry Sue, you don't get out of it that easily!!
>>>
>>>
>>>
>>> On Feb 5, 2008, at 3:40 PM, Sue Rhee wrote:
>>>
>>>> Hi GO and Phenoscape colleagues,
>>>>
>>>> Larry Hunter pointed me to the OBI project 
>>>> (http://obi.sourceforge.net) recently, which I wasn't aware of. It 
>>>> seems to me that the ECO is redundant to and much less developed 
>>>> than the OBI and I would like to suggest that OBI take over merging 
>>>> ECO into their ontology. Please let me know if you have any views 
>>>> on this.
>>>>
>>>> Best,
>>>> Sue
>>>>
>>>> -- 
>>>> Sue Rhee
>>>> Staff Scientist
>>>> Carnegie Institution, Department of Plant Biology
>>>> 260 Panama Street, Stanford, CA 94305
>>>> Email: (650) 325-1521 x251
>>>> Fax: (650) 325-6857
>>>>
>>>>
>>>
>>>
>

-- 
Helen Parkinson, PhD
ArrayExpress Production Coordinator,
Microarray Informatics Team, 
EBI

EBI 01223 494672
Skype: helen.parkinson.ebi




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