[go] concern about 'tricarboxylic acid cycle intermediate metabolic process' GO:0006100
Midori Harris
midori at ebi.ac.uk
Thu Feb 21 08:15:01 PST 2008
Hi all,
In SF 1894620, I corrected a true path violation for 'TCA cycle'
(GO:0006099) that Peter D'Eustachio noticed. That work also brought
'tricarboxylic acid cycle intermediate metabolic process' (GO:0006100) to
our attention. It has the same parent -- 'cellular carbohydrate metabolic
process' (GO:0044262) -- that caused the TPV for TCA cycle, but has no
other parents. Peter and I reached the conclusion that GO:0006100 serves
merely as a grouping term from "metabolism of molecules that make an
appearance in the TCA cycle", and that, while not entirely nonsense,
having 'cycle intermediates' process terms is a really rich sources of
tpv's.
We therefore suggest that the safest course of action is to make
GO:0006100 obsolete. Annotations can be transferred to TCA cycle or to one
of the children of GO:0006100.
Before I start the procedure to make GO:0006100 obsolete, can anyone
recall or think of any reasons to keep the term? If we do, I think it
would have to go directly under cellular metabolic process.
https://sourceforge.net/tracker/index.php?func=detail&aid=1894620&group_id=36855&atid=440764
Midori
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