[go] Alert: DNA polymerase terms to be merged

[Midori Harris]

Hello,

In SF 1898404 Chris observed that 'DNA-directed DNA polymerase activity' 
(GO:0003887) and many of its children have identical definitions; in SF 
1192485 several curators observed that the child terms actually represent 
gene products. All catalyze the same template-directed polymerization 
reaction by the same mechanism (e.g. see review PMID: 12045093). The 
differences include subunit structure, other activities present in the 
polymerase (whether monomeric or multimeric), and involvement in various 
processes (DNA replication, DNA repair, etc.). Most of this can be 
captured using additional annotations, including component and process 
terms.

To minimize annotation upheaval, I propose to merge the following terms 
into their parent, 'DNA-directed DNA polymerase activity' (GO:0003887):

 	alpha DNA polymerase activity ; GO:0003889
 	beta DNA polymerase activity ; GO:0003890
 	delta DNA polymerase activity ; GO:0003891
 	DNA polymerase V activity ; GO:0008723
 	epsilon DNA polymerase activity ; GO:0003893
 	eta DNA polymerase activity ; GO:0015999
 	gamma DNA polymerase activity ; GO:0003895
 	iota DNA polymerase activity ; GO:0016000
 	kappa DNA polymerase activity ; GO:0016450
 	lambda DNA polymerase activity ; GO:0016449
 	mu DNA polymerase activity ; GO:0016448
 	nu DNA polymerase activity ; GO:0016451
 	sigma DNA polymerase activity ; GO:0019984
 	theta DNA polymerase activity ; GO:0016452
 	zeta DNA polymerase activity ; GO:0003894

SourceForge links:
https://sourceforge.net/tracker/index.php?func=detail&aid=1192485&group_id=36855&atid=440764
https://sourceforge.net/tracker/index.php?func=detail&aid=1898404&group_id=36855&atid=440764

*** Unless objections are received by Tuesday, March 4, 2008,
      we will assume you agree to this change. ***

Midori