[go] Alert: proposal to obsolete GO:0045192 (cellular component), which affects existing annotation

[Midori Harris]

addendum to reason for obsoleting included below

On Tue, 15 Jan 2008, Midori Harris wrote:

> The proposal has been made to obsolete
>
>  low-density lipoprotein catabolic process ; GO:0045192
>
> Annotations to this term exist at present as follows:
>
>  UniProtKB:P01130	IEA
>  UniProtKB:Q14162	TAS
>  UniProtKB:Q15036	NAS
>
>  MGI:96765	IDA, IMP
>
>  RGD:1306424	ISS
>  RGD:1309330	ISS
>
> This term is not used in any external2go mappings, and is not used in any GO 
> slim set maintained within the OBO flat file.
>

The reason for this proposal is that low-density lipoprotein is a 
macromolecular complex, and its degradation involves the dissociation of 
non-covalently attached constituents as well as some breaking and 
reforming of covalent bonds. The process is therefore better represented 
as a complex disassembly term.

>
> SourceForge link:
> https://sourceforge.net/tracker/index.php?func=detail&aid=1854029&group_id=36855&atid=440764
>
> The two-week comment period ends on Wednesday, January 30, 2008.
>
> *** Unless objections are received by January 30,
>    we will assume that you agree to this change. ***
>