[Go] 1 year limit on IEAs
Daniel Barrell
dbarrell at ebi.ac.uk
Tue Jun 10 00:34:22 PDT 2008
What Harold and Mike have described is correct. The mapping files
(ec2go, hamap2go, interpro2go, etc) are sanity checked on a weekly basis
and corrected/extended by curators if needs be. The IEA pipeline is run
3 weekly after each UniProt release (so, realistically, monthly).
If you are parsing our files directly you should do it at least annually
to conform to the GO 1 year rule, but ideally you'd be taking them far
more often.
Cheers
Dan
Mike Cherry wrote:
> UNIPROTs IEA are updated with each of their monthly releases. So if you
> get their IEAs at least once a year you're fine.
>
> The 1 year limit was set way back. I think back in 2001 for the reasons
> Suzanna gave. If the IEAs cannot be updated once a year how actuate are
> they?
>
> -Mike
>
>
> On Jun 9, 2008, at 10:34 AM, Harold Drabkin wrote:
>
>> Jim, if I'm not mistaken (someone from UniProt chime in please) , the
>> IEAs from UniProt are based on the translation files (ec2go, ip2go and
>> spkw2go) based on information in a uniprot record (ec#, domains,
>> keywords). These change frequently; sometimes domains get added or
>> removed, or the translation files change (mappings that are suddently
>> to recently obsoleted terms, eg.) and so the IEAs go stale, espeically
>> after 1 year. We update daily. I would really worry if they were older
>> than 1 month,l et alone a year.
>>
>> hjd
>>
>> Jim Hu wrote:
>>> Hi All,
>>>
>>> As I recall, this was discussed at the SLC consortium meeting, but I
>>> find that I can't reconstruct the rationale for the 1 year expiration
>>> date on IEAs. For E. coli, we're importing the IEAs from Uniprot,
>>> but most of them will expire almost immediately. I assume that there
>>> is a problem in other genomes of too many IEAs. But perhaps a limit
>>> on how many per gene or some such might be more flexible.
>>> For our E. coli websites, I think it makes sense to display IEAs with
>>> appropriate caveats, since we're trying to encourage the community to
>>> do quality control on them. But I'm not sure, and I imagine that
>>> other mods have thought about this a lot.
>>>
>>> Jim
>>>
>>> =====================================
>>>
>>> Jim Hu
>>>
>>> Associate Professor
>>>
>>> Dept. of Biochemistry and Biophysics
>>>
>>> 2128 TAMU
>>>
>>> Texas A&M Univ.
>>>
>>> College Station, TX 77843-2128
>>>
>>> 979-862-4054
>>>
>>>
>>>
>>> ------------------------------------------------------------------------
>>>
>>> _______________________________________________
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>>
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--
Daniel Barrell
EMBL - The EBI
Wellcome Trust Genome Campus
Hinxton, Cambridge CB10 1SD
Phone: +44 (0)1223 492551
Email: dbarrell at ebi.ac.uk
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