[Go] Alert: proposal to obsolete GO:0030508 that impacts existing annotations

Midori Harris midori at ebi.ac.uk
Thu May 8 08:59:53 PDT 2008


Dear GO,

The proposal has been made to obsolete

   thiol-disulfide exchange intermediate activity ; GO:0030508

Annotations to GO:0009935 exist as listed below:

 	DB	total
 	GeneDB_Pfalciparum	4 (1 TAS, 3 ISS)
 	GeneDB_Spombe	10 (several codes; no IEA)
 	GeneDB_Tbrucei	5 (all ISS)
 	CGD	5 (2 IEA, 3 NAS)
 	dictyBase	12 (several codes; no IEA)
 	FB	22 (several codes; no IEA))
 	GOA_human	5 (2 IDA, 3 TAS)
 	MGI	1 (IDA)
 	Pseudocap	4 (all RCA)
 	RGD	5 (several codes; 1 IEA)
 	SGD	16 (several codes; no IEA)
 	TAIR	92 (1 ISS; rest RCA)
 	tigr_Aphagocytophilum	3 (all ISS)
 	tigr_Banthracis	5 (all ISS)
 	tigr_Cburnetii	4 (all ISS)
 	tigr_Chydrogenoformans	6 (all ISS)
 	tigr_Cjejuni	6 (all ISS)
 	tigr_Cperfringens	5 (all ISS)
 	tigr_Cpsychrerythraea	13 (all ISS)
 	tigr_Dethenogenes	3 (all ISS)
 	tigr_Echaffeensis	2 (all ISS)
 	tigr_Gsulfurreducens	7 (all ISS)
 	tigr_Hneptunium	4 (all ISS)
 	tigr_Lmonocytogenes	5 (all ISS)
 	tigr_Mcapsulatus	4 (all ISS)
 	tigr_Nsennetsu	2 (all ISS)
 	tigr_Pfluorescens	6 (all ISS)
 	tigr_Psyringae	5 (all ISS)
 	tigr_Psyringae_phaseolicola	4 (all ISS)
 	tigr_Soneidensis	7 (all ISS)
 	tigr_Spomeroyi	5 (all ISS)
 	tigr_Vcholerae	6 (all ISS)

The reason for obsoleting this term is that it represents a combination of 
gene product features and involvement in a biological process. Terms 
suggested for annotation updates:

   protein thiol-disulfide exchange ; GO:0006467 (BP)
   disulfide oxidoreductase activity ; GO:0015036 (MF)

This term is in the prokaryote subset, but not in any GO slims maintained 
in the gene_ontology_write.obo file. It is used in two external mappings:

tigrfams2go:TIGR_TIGRFAMS:TIGR01068 thioredoxin > GO:thiol-disulfide 
exchange intermediate activity ; GO:0030508

tigrfams2go:TIGR_TIGRFAMS:TIGR02181 glutaredoxin 3 > GO:thiol-disulfide 
exchange intermediate activity ; GO:0030508

SourceForge link:
https://sourceforge.net/tracker/index.php?func=detail&aid=1036091&group_id=36855&atid=440764

Comment period ends on May 27, 2008.

*** Unless objections are received by May 27,
     we will assume that you agree to this change. ***

Thanks,
Midori




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