[Go] Alert: proposal to obsolete GO:0006280 that impacts existing annotations

Midori Harris midori at ebi.ac.uk
Mon May 12 08:36:52 PDT 2008


Dear GO,

The proposal has been made to obsolete

   mutagenesis ; GO:0006280

Annotations to GO:0006280 exist as listed below:

  	DB	total
  	CGD	5 (all IEA)
  	dictyBase	1 (ISS)
  	GOA_human	1 (TAS)
 	GOA_uniprot	17 (all IEA)
  	SGD	13 (several codes; no IEA)
  	tigr_Banthracis	1 (ISS)
  	tigr_Soneidensis	3 (all ISS)
 	WB	5 (all IMP)

The reason for obsoleting this term is that mutagenesis is not a valid 
biological process in which gene products would normally participate. 
Rather, mutations arise from DNA replication errors or damage by an 
extrinsic agent. Terms suggested for annotation updates:

   DNA repair ; GO:0006281
   chromosome organization and biogenesis ; GO:0051276

This term is in the prokaryote subset, but not in any GO slims maintained
in the gene_ontology_write.obo file. It is used in one external mapping:

spkw2go:SP_KW:KW-0741 SOS mutagenesis > GO:mutagenesis ; GO:0006280

SourceForge link:
https://sourceforge.net/tracker/index.php?func=detail&aid=1683673&group_id=36855&atid=440764

Comment period ends on May 28, 2008.

*** Unless objections are received by May 28,
      we will assume that you agree to this change. ***

Thanks,
Midori


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