[Go] ec2go question

[Doug]

Does anyone know if the format/content of the ec2go translation file  
changed recently (past few weeks)?  I am seeing some strange IEA  
annotations in our set which derive from ec2go.
See our sult1st2 gene for example:

http://zfin.org/cgi-bin/webdriver?MIval=aa-markergoview.apg&OID=ZDB-GENE-030804-27

the EC:2.8.2.- was translated, as shown in the ec2go file, to a whole  
host of sulfotransferase activities.  Is this a problem with ec2go, or  
has something gone wild on our end?

Here are the ec2go lines which were translated:
EC:2.8.2.- > GO:N-acetylglucosamine 6-O-sulfotransferase activity ; GO: 
0001517
EC:2.8.2.- > GO:N-acetylgalactosamine 4-O-sulfotransferase activity ;  
GO:0001537
EC:2.8.2.- > GO:heparan sulfate 2-O-sulfotransferase activity ; GO: 
0004394
EC:2.8.2.- > GO:HNK-1 sulfotransferase activity ; GO:0016232
EC:2.8.2.- > GO:heparan sulfate 6-O-sulfotransferase activity ; GO: 
0017095
EC:2.8.2.- > GO:trans-9R,10R-dihydrodiolphenanthrene sulfotransferase  
activity ; GO:0018721
EC:2.8.2.- > GO:1-phenanthrol sulfotransferase activity ; GO:0018722
EC:2.8.2.- > GO:3-phenanthrol sulfotransferase activity ; GO:0018723
EC:2.8.2.- > GO:4-phenanthrol sulfotransferase activity ; GO:0018724
EC:2.8.2.- > GO:trans-3,4-dihydrodiolphenanthrene sulfotransferase  
activity ; GO:0018725
EC:2.8.2.- > GO:9-phenanthrol sulfotransferase activity ; GO:0018726
EC:2.8.2.- > GO:2-phenanthrol sulfotransferase activity ; GO:0018727
EC:2.8.2.- > GO:phenanthrol sulfotransferase activity ; GO:0019111
EC:2.8.2.- > GO:1-hydroxypyrene sulfotransferase activity ; GO:0034930
EC:2.8.2.- > GO:galactose 3-O-sulfotransferase activity ; GO:0050694
EC:2.8.2.- > GO:proteoglycan sulfotransferase activity ; GO:0050698
EC:2.8.2.- > GO:cholesterol sulfotransferase activity ; GO:0051922

I assume that the assignment of EC:2.8.2.- to this gene product does  
not mean that it has all of those sulfotransferase activities..but  
instead means it should have at least one of them???


Doug Howe, Ph.D.
Scientific Curator
Zebrafish Nomenclature Coordinator
Zebrafish Information Network
541-346-0120
dhowe at cs.uoregon.edu