[Go] question about download page

Midori Harris midori at ebi.ac.uk
Thu Apr 16 10:20:14 PDT 2009


My guess would be that TAS isn't placed correctly; it's been a last-resort 
code used in manual annotation, when a curator is inclined to believe 
something an author says despite being unable to track down an experiment. 
I'm not aware of it being used for any kind of computational analysis.

m

On Thu, 16 Apr 2009, Chris Mungall wrote:

> We should be using ECO here rather than hardcoding ad-hoc lists of codes in 
> various pieces of code
>
> There should be some explicitly declared property in ECO that RCA and IEA 
> share - either via shared is_a parent or via a relationship to some aspect of 
> the type of evidence.
>
> At the moment we have:
>
> is_a ECO:0000043 ! inferred from in-silico analysis
>  is_a ECO:00000067 ! inferred from electronic annotation ***  [SYNONYM: 
> "IEA" (related)]
>  is_a ECO:0000033 ! traceable author statement [SYNONYM: "TAS" (related)]
>  is_a ECO:0000053 ! inferred from reviewed computational analysis *** 
> [SYNONYM: "RCA" (related)]
>
> Which seems dubious. If TAS is placed correctly then we can perhaps use 
> inferred from in-silico analysis. But I think ECO needs further 
> re-arrangement or changes such that we have an evidence type "inferred SOLELY 
> from in-silico analysis"
>
> On Apr 16, 2009, at 8:01 AM, Valerie Wood wrote:
>
>> 
>> 
>> On the download page, the number of annotations for each organism are 
>> reported and the number of these which are IEA are specified.
>> Should this also specify the number which are non-RCA (as these are 
>> generally function predictions, with less support than the IEA mappings, 
>> and users should be made as aware of the 'dangers' of these,  as of the IEA 
>> data).
>> 
>> Val
>> 
>> 
>> -- 
>> The Wellcome Trust Sanger Institute is operated by Genome Research Limited, 
>> a charity registered in England with number 1021457 and a company 
>> registered in England with number 2742969, whose registered office is 215 
>> Euston Road, London, NW1 2BE. 
>> _______________________________________________
>> Go mailing list
>> Go at geneontology.org
>> http://fafner.stanford.edu/mailman/listinfo/go
>> 
>
> _______________________________________________
> Go mailing list
> Go at geneontology.org
> http://fafner.stanford.edu/mailman/listinfo/go


More information about the Go mailing list