[Go] question about download page
Karen Christie
kchris at genome.stanford.edu
Thu Apr 16 10:26:33 PDT 2009
I agree that TAS is not placed correctly in the ECO. This is one of the
things that I commented upon a while ago, when the evidence code
documentation was under revision. Michelle Gwinn said she's working on the
ECO now and I recently sent her my whole list of comments/questions on the
ECO.
-Karen
On Thu, 16 Apr 2009, Midori Harris wrote:
> My guess would be that TAS isn't placed correctly; it's been a last-resort
> code used in manual annotation, when a curator is inclined to believe
> something an author says despite being unable to track down an experiment.
> I'm not aware of it being used for any kind of computational analysis.
>
> m
>
> On Thu, 16 Apr 2009, Chris Mungall wrote:
>
>> We should be using ECO here rather than hardcoding ad-hoc lists of codes in
>> various pieces of code
>>
>> There should be some explicitly declared property in ECO that RCA and IEA
>> share - either via shared is_a parent or via a relationship to some aspect
>> of the type of evidence.
>>
>> At the moment we have:
>>
>> is_a ECO:0000043 ! inferred from in-silico analysis
>> is_a ECO:00000067 ! inferred from electronic annotation *** [SYNONYM:
>> "IEA" (related)]
>> is_a ECO:0000033 ! traceable author statement [SYNONYM: "TAS" (related)]
>> is_a ECO:0000053 ! inferred from reviewed computational analysis ***
>> [SYNONYM: "RCA" (related)]
>>
>> Which seems dubious. If TAS is placed correctly then we can perhaps use
>> inferred from in-silico analysis. But I think ECO needs further
>> re-arrangement or changes such that we have an evidence type "inferred
>> SOLELY from in-silico analysis"
>>
>> On Apr 16, 2009, at 8:01 AM, Valerie Wood wrote:
>>
>>>
>>>
>>> On the download page, the number of annotations for each organism are
>>> reported and the number of these which are IEA are specified.
>>> Should this also specify the number which are non-RCA (as these are
>>> generally function predictions, with less support than the IEA mappings,
>>> and users should be made as aware of the 'dangers' of these, as of the
>>> IEA data).
>>>
>>> Val
>>>
>>>
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>>
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