[Go] Binding call at 11 EDT today

[Judith Blake]

Hi,
I'll be a little late today, but will call in at the end.  Here are some 'go-top' type thoughts on this, but this also incorporates the GO at MGI specific thoughts as well.  I look forward to a considerate discussion.

Judy

We...

 1.  support everyone who have sought to clarify the binding discussion; update documentation,
 2.  recognize that the binding discussion is confounded by complexity of assays and kinetics of 'binding' studies,
 3.  commit to 'annotating to the experiment' meaning trying to capture the specifics as much as feasible; use the binding term if the experiment shows binding, don't use if experiment shows catalysis but not specific binding the gene product,
 4.  reaffirm our commitment to provide practical and useful data to enhance the work of biologists,
 5.  remember that 'consistency' is a principle, not a rule; there will be exceptions: here what is needed is a statement of standard, such as provided in '3'. The goal is to have 'correct' annotations, not that everyone should have the same annotation,
 6.  consider that if existing annotations (~8,000?) involving binding terms are not wrong, then we should strongly consider keeping them,
 7.  and, confirm that any global change will need approval by GO-top
 8.
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