[Go] Binding call at 11 EDT today

[Ruth Lovering]

Hi Judy

thanks for these comments.  I will add them to the conference call wiki

Ruth

On 11 Jun 2009, at 15:35, Judith Blake wrote:

> Hi,
> I’ll be a little late today, but will call in at the end.  Here are  
> some ‘go-top’ type thoughts on this, but this also incorporates the  
> GO at MGI specific thoughts as well.  I look forward to a considerate  
> discussion.
>
> Judy
>
> We...
> support everyone who have sought to clarify the binding discussion;  
> update documentation,
> recognize that the binding discussion is confounded by complexity of  
> assays and kinetics of ‘binding’ studies,
> commit to ‘annotating to the experiment’ meaning trying to capture  
> the specifics as much as feasible; use the binding term if the  
> experiment shows binding, don’t use if experiment shows catalysis  
> but not specific binding the gene product,
> reaffirm our commitment to provide practical and useful data to  
> enhance the work of biologists,
> remember that ‘consistency’ is a principle, not a rule; there will  
> be exceptions: here what is needed is a statement of standard, such  
> as provided in ‘3’. The goal is to have ‘correct’ annotations, not  
> that everyone should have the same annotation,
> consider that if existing annotations (~8,000?) involving binding  
> terms are not wrong, then we should strongly consider keeping them,
> and, confirm that any global change will need approval by GO-top

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