[Go] Alert: proposal to obsolete two molecular function terms that impacts existing annotations
Midori Harris
midori at ebi.ac.uk
Mon Mar 16 08:11:28 PDT 2009
Dear GO,
The proposal has been made to obsolete
apolipoprotein E receptor activity ; GO:0030227
apolipoprotein E receptor binding ; GO:0050749
Annotations to these terms exist as listed below:
gene_association.goa_cow.gz
GO ID IEA non-IEA total
GO:0050749 1 0 1
gene_association.goa_human.gz
GO ID IEA non-IEA total
GO:0030227 0 1 1
gene_association.goa_uniprot.gz
GO ID IEA non-IEA total
GO:0050749 5 0 5
gene_association.rgd.gz
GO ID IEA non-IEA total
GO:0030227 0 1 1
GO:0050749 1 0 1
The reason for obsoleting these terms is that no known receptor binds
apolipoprotein E; instead, receptors bind holo-lipoprotein E
(apolipoprotein E + bound lipid).
Annotations should be transferred to VLDL receptor terms:
very-low-density lipoprotein receptor activity ; GO:0030229
very-low-density lipoprotein receptor binding ; GO:0070326
These terms are not in any GO slim or subset maintained in the GO .obo
files, and are not used in any external mappings.
SourceForge link:
https://sourceforge.net/tracker/index.php?func=detail&aid=2686128&group_id=36855&atid=440764
Comment period ends on March 31, 2009.
*** Unless objections are received by March 31,
we will assume that you agree to this change. ***
Thanks,
Midori
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