[gofriends] GO visualisation tool?
Sorin Draghici
sod at cs.wayne.edu
Sun Jan 13 20:38:46 PST 2008
Hi,
A list of such tools together with an extensive discussion is available in:
Purvesh Khatri and Sorin Draghici. Ontological analysis of gene expression data:
current tools, limitations, and open problems. Bioinformatics, 21(18):3587-95,
September 2005.
The paper is available here:
http://vortex.cs.wayne.edu/papers/Ontological_analysis.pdf
Regards,
Sorin Draghici, Ph.D.
Director of the Bioinformatics Core, Karmanos Cancer Institute
Associate Professor Tel: (313) 577-5484
Dept. of Computer Science Fax: (313) 577-6868
Wayne State University
5143 Cass Ave, Room 431 State Hall,
Detroit, MI, 48202
WWW: http://vortex.cs.wayne.edu/Sorin/index.htm (personal)
WWW: http://vortex.cs.wayne.edu/Projects.htm (lab)
Check out my recent book: Data Analysis Tools for Microarrays:
http://www.crcpress.com/shopping_cart/products/product_detail.asp?sku=C3154&parent_id=&pc=
Jim Hu wrote:
> Hi Rachael,
>
> On Jan 10, 2008, at 10:00 AM, Rachael Huntley wrote:
>
>> Hi Jim,
>>
>> He has done a microarray experiment and wants to cluster the genes
>> according to GO, so he wants to see the GO tree with the genes
>> displayed under the GO terms they are annotated to. I don't think
>> AmiGO does this sort of thing.
>
> Ah, that makes sense. So, if I understand this right, a general tool
> would be something where you give a program the ontology, a gene
> association file, and a list of genes, and get the appropriate display.
> This has to be filtered for statistically enriched associations to be
> useful, I think. I'm interested to see what others suggest. I think
> that various projects have their own organism-specific versions of this,
> and I think it's built into commercial packages like GeneSpring. But
> I'd like to see a list and discussion of what's available as open
> source... especially for things that can be displayed as web tools.
>
> Jim
>
>>
>>
>> Rachael.
>>
>> Jim Hu wrote:
>>
>>> Hi Rachael,
>>>
>>> I'm not sure I understand what the user wants to do. Doesn't AmiGO
>>> place genes under the appropriate branches based on annotations? Is
>>> this not the desired kind of visualization? Or do they want
>>> something different?
>>>
>>> Jim
>>>
>>>
>>> On Jan 10, 2008, at 7:46 AM, Rachael Huntley wrote:
>>>
>>>> Dear all,
>>>>
>>>> I have had this query from a user, does anyone know of a tool that
>>>> can do this?
>>>>
>>>> >Do you know of any GO viewer that allows you to visualise the GO
>>>> structure and place genes with a specific annotation under that
>>>> branch of the tree?
>>>> <
>>>>
>>>> Thanks,
>>>> Rachael.
>>>>
>>>> --
>>>> Rachael Huntley Ph.D.
>>>>
>>>> European Bioinformatics Institute-EMBL
>>>> Wellcome Trust Genome Campus
>>>> Hinxton
>>>> Cambridge CB10 1SD
>>>> United Kingdom Tel: +44 (0)1223 492515
>>>> Fax: +44 (0)1223 494468
>>>>
>>>> E-mail: huntley at ebi.ac.uk <mailto:huntley at ebi.ac.uk>
>>>> URL: http://www.ebi.ac.uk/GOA
>>>>
>>>>
>>>> --
>>>> This message is from the GOFriends moderated mailing list. A list
>>>> of public
>>>> announcements and discussion of the Gene Ontology (GO) project.
>>>> Problems with the list? E-mail:
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>>>
>>>
>>> =====================================
>>>
>>> Jim Hu
>>>
>>> Associate Professor
>>>
>>> Dept. of Biochemistry and Biophysics
>>>
>>> 2128 TAMU
>>>
>>> Texas A&M Univ.
>>>
>>> College Station, TX 77843-2128
>>>
>>> 979-862-4054
>>>
>>>
>>>
>>
>>
>> --
>>
>> Do you need any additional GO annotation resources?
>> Which proteins would you like annotated with GO?
>>
>> Let us know in the GOA User Survey, available at
>> http://www.ebi.ac.uk/GOA/contactus.html
>>
>>
>> *************************************
>>
>> Rachael Huntley Ph.D.
>>
>> European Bioinformatics Institute-EMBL
>> Wellcome Trust Genome Campus
>> Hinxton
>> Cambridge CB10 1SD
>> United Kingdom
>> Tel: +44 (0)1223 492515
>> Fax: +44 (0)1223 494468
>>
>> E-mail: huntley at ebi.ac.uk <mailto:huntley at ebi.ac.uk>
>> URL: http://www.ebi.ac.uk/GOA
>>
>
> =====================================
>
> Jim Hu
>
> Associate Professor
>
> Dept. of Biochemistry and Biophysics
>
> 2128 TAMU
>
> Texas A&M Univ.
>
> College Station, TX 77843-2128
>
> 979-862-4054
>
>
>
--
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