[immunology] IFN induction to GO mapping

camon at ebi.ac.uk camon at ebi.ac.uk
Mon Oct 8 07:00:07 PDT 2007


Hi

UniProtKB have a keyword 'Interferon induction' which they assign to
proteins that are induced by interferon. They are asking if they can map
this to the GO term 'immune response'.

Suggestions? Its a bit of a strange kw.

Here is the DEFINITION:

ID   Interferon induction.
AC   KW-0402
DE   Protein induced by interferon(s). Interferons are a class of cytokines
DE   which mediate, by binding to specific cell-surface receptors, a broad
DE   range of activities such as resistance to viral infection, modulation
DE   of the immune response and regulation of proliferation of normal and
DE   malignant cells.
SY   IFN induction.

and here are the proteins with that annotation:

http://ca.expasy.org/cgi-bin/get-entries?KW=Interferon%20induction

Evelyn





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