axon regeneration as part of differentiation?

[Doug Howe]

I wanted to see if anyone else in the Neuro interest group thought there 
was an issue here before I posted a SF tracker item on it. 

The term GO:0031103 'axon regeneration' has 'neuron morphogenesis during 
differentiation' in it's path to root. This means that the process of 
'axon regeneration' in GO is implicitly restricted to occur during 
neuron differentiation.   This doesn't seem correct to me.  It seems to 
me that 'axon regeneration' is the extenstion of an axon by a mature 
neuron (ie not a differentiating neuron) after loss of the axon for some 
reason.  This process doesn't involve de-differentiation and 
re-differentiation of the neuron.

 Does anyone else see it that way?

I'm not in tune with the current biology on this, so I could be incorrect.

-Doug

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Doug Howe, Ph.D.
ZFIN Scientific Curator
Zebrafish Information Network
5291 University of Oregon
Eugene, OR 97403-5291

Phone: (541) 346-5733
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