neuroblast vs. neuronal progenitor
Nicolas Le Novère
lenov at ebi.ac.uk
Mon May 22 15:05:15 PDT 2006
I am not entirely sure about that (mostly because I'm writting that
looking at telly during an advert break in the middle of Farenheit 9/11.
Pretty hard to concentrate on anything else), but I think neuroblasts are
definitely progenitors of both neurons AND glial cells. I.e. neuronal
precursors form a paraontogenic group (based on paraphyletic). I am almost
sure of that for Bergman glia.
> Would everyone agree if I were to suggest that all GO terms that have
> "neuroblast" in the term name also have an exact synonym using the term
> "neuronal progenitor"?
>
> Eg.
> "neuroblast differentiation" would get an exact synonym of "neuronal
> progenitor differentiation".
>
> Likewise, I would like to suggest a new term on SourceForge for
> "glioblast differentiation" with the exactly synonym "glial progenitor
> differentiation".
>
> I realize that sometimes a single cells can pass through a stage during
> which it is a progenitor capable of generating neurons and glia in some
> cases..but I think this is OK..maybe we could even have a term like
> "neuro-glial progenitor differentiation" to represent differentiation of
> this type of cell?
>
> What do you think?
>
> -Doug
>
--
Nicolas LE NOVÈRE, Computational Neurobiology,
EMBL-EBI, Wellcome-Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
Tel: +44(0)1223 494 521, Fax: +44(0)1223 494 468, Mob: +33(0)689218676
http://www.ebi.ac.uk/~lenov
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