[Ontology-editors] use of regulates

[David Hill]

Hi Jane,

We think this is also fine. The bottom line is that an organism should 
be allowed to regulate a cellular process in another organism. Although 
it would be more complete to create the term 'regulation of 
cAMP-mediated signalling' and then make 'modulation by host of symbiont 
cAMP-mediated signaling' or even better 'modulation of symbiont 
cAMP-mediated signaling by host' an is_a child of this new term.

David and Tanya

Midori Harris wrote:
> I think this would be fine. Disjointness only applies to is_a, and we 
> already have lots of cellular processes that are (sometimes indirectly)
> part_of some MCOP or MOP. There are probably also regulates examples, 
> but I would have to search to make sure.
>
> We might want 'regulation of cAMP-mediated signaling' anyway if there 
> would be any other children besides the modulation by host etc. one.
>
> m
>
> On Thu, 31 Jul 2008, Jane Lomax wrote:
>
>> Also, can I make regulates relationships directly between the MOP 
>> terms and non-MOP process terms? For example:
>>
>> modulation by host of symbiont cAMP-mediated signaling -regulates-> 
>> cAMP-mediated signaling
>>
>> Or do I need to make a 'regualtion of cAMP-mediated signaling' term?
>>
>> Does it matter that 'regualtion of cAMP-mediated signaling' would be 
>> a 'regulation of cellular process'? (I know we haven't tried to apply 
>> disjointness to any of the regulation terms, but just seems wrong 
>> somehow!)
>>
>> Jane
>>
>>
>>
>> Jane Lomax wrote:
>>> Hi Chris, David and Tanya - I'm in the midst of creating a load of 
>>> new terms for PAMGO, and I'm trying to get the regulates 
>>> relationships correct as I go to save pain in the future. It works 
>>> so differently from the other all-some relations we use I'm having a 
>>> hard time getting my head around it.
>>>
>>> For example, in a situation where you have a term 'regulation of 
>>> process X' but there's no process X in GO, but process X is_a 
>>> process Y, is it okay to say that 'regulation of process X' 
>>> regulates process Y? Or do we have to create a process X?
>>>
>>> Jane
>>>
>>
>>
>>
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