[Ontology-editors] use of regulates

Midori Harris midori at ebi.ac.uk
Wed Aug 6 04:12:30 PDT 2008


On Tue, 5 Aug 2008, Chris Mungall wrote:

> We would have to make a single explicit disjoint_from statement between 
> RoMCOP and RoMOP to prohibit nodes from having is_a lineage in both. But I 
> don't think we would want to do this.

My gut reaction is that it wouldn't be biologically accurate to make 
RoMCOP and RoMOP disjoint -- I can imagine an instance of regulation of 
some MCOP that also ends up having a regulatory effect on some MOP in 
which the MCO was involved. (Or is is_a not the right relation to use for 
that scenario?)

m


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