[Ontology-editors] forward and reverse transcription

Harold Drabkin hjd at informatics.jax.org
Mon Dec 1 08:33:57 PST 2008


Hmm, from  the def of 64101, the term name really doesn't fit, since to 
me, RNA -dependent transcription would be a process whereby an RNA 
template is transcribed to create another RNA molecule. As it's defined, 
it is "reverse" transcription.
Based on the def, I would vote to merge them.
Posted to SF also


Midori Harris wrote:
> Hi,
>
> A couple of questions have come up in SF 2354289:
>
> 1. Should these terms be merged?
>
>   id: GO:0006278
>   name: RNA-dependent DNA replication
>   def: "The process whereby new strands of DNA are synthesized, using RNA
>   as a template for RNA-dependent DNA polymerases (e.g. reverse
>   transcriptase) that synthesize the new strands."
>
>   id: GO:0006410
>   name: transcription, RNA-dependent
>   namespace: biological_process
>   def: "The synthesis of DNA on a template of RNA."
>
> 2. Should reverse transcription be considered part of gene expression 
> (at present it is, by transitivity, but if it shouldn't be, it's easy 
> to change)?
>
> Comments here or on the SF item much appreciated.
>
> https://sourceforge.net/tracker/index.php?func=detail&aid=2354289&group_id=36855&atid=440764 
>
>
> Midori
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