[Ontology-editors] forward and reverse transcription
David Hill
dph at informatics.jax.org
Mon Dec 1 08:40:19 PST 2008
I agree with Harold. Reverse transcription refers to the process of
reversing the transcription process, not a type of transcription.
Harold Drabkin wrote:
> Hmm, from the def of 64101, the term name really doesn't fit, since
> to me, RNA -dependent transcription would be a process whereby an RNA
> template is transcribed to create another RNA molecule. As it's
> defined, it is "reverse" transcription.
> Based on the def, I would vote to merge them.
> Posted to SF also
>
>
> Midori Harris wrote:
>> Hi,
>>
>> A couple of questions have come up in SF 2354289:
>>
>> 1. Should these terms be merged?
>>
>> id: GO:0006278
>> name: RNA-dependent DNA replication
>> def: "The process whereby new strands of DNA are synthesized, using
>> RNA
>> as a template for RNA-dependent DNA polymerases (e.g. reverse
>> transcriptase) that synthesize the new strands."
>>
>> id: GO:0006410
>> name: transcription, RNA-dependent
>> namespace: biological_process
>> def: "The synthesis of DNA on a template of RNA."
>>
>> 2. Should reverse transcription be considered part of gene expression
>> (at present it is, by transitivity, but if it shouldn't be, it's easy
>> to change)?
>>
>> Comments here or on the SF item much appreciated.
>>
>> https://sourceforge.net/tracker/index.php?func=detail&aid=2354289&group_id=36855&atid=440764
>>
>>
>> Midori
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--
David P. Hill, Ph.D.
Bioinformatics Scientist: Ontology Development
Gene Ontology Consortium
The Jackson Laboratory
www.geneontology.org
www.informatics.jax.org
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