[Ontology-editors] constituent part

Jane Lomax jane at ebi.ac.uk
Tue Jul 8 06:40:05 PDT 2008


That would be good. However, we still have the problem that we can't 
hide disjoint relations in OE1, so I'd be a bit wary about adding any 
more until we're using OE2 as it makes the graph view very tangled...



Chris Mungall wrote:
>
> I think we should add a disjoint relation between "cell part" and 
> "extracellular region part" (to allow OE to auto-detect other errors 
> of this sort)
>
> See:
> http://wiki.geneontology.org/index.php/Cellular_component_disjoint_classes 
>
>
> On Jul 8, 2008, at 12:41 PM, Jane Lomax wrote:
>
>> Looks like this is the offending relationship:
>>
>> / GO:0005576 extracellular region
>>  po GO:0020008 rhoptry {via is_a extracellular region part}
>>
>> I can't find anything in the literature to indicate that the rhoptry 
>> is extracellular (see 
>> http://www.nature.com/nrmicro/journal/v6/n1/fig_tab/nrmicro1800_F3.html). 
>> Anyone object if I go ahead and delete this relationship?
>>
>> Jane
>>
>>
>>
>> Chris Mungall wrote:
>>>
>>> Actually if constituent has no special meaning then the reasoner is 
>>> correct (the links are not asserted & the reasoner is inferring the 
>>> links)
>>>
>>>  / GO:0005576 extracellular region
>>>   po GO:0020008 rhoptry {via is_a extracellular region part}
>>>  / GO:0005623 cell
>>>   po GO:0045177 apical part of cell {via is_a cell part}
>>>    po GO:0020007 apical complex
>>>     po GO:0020008 rhoptry
>>>
>>>
>>> On Jul 8, 2008, at 11:48 AM, Jane Lomax wrote:
>>>
>>>> Chris - I don't think 'constituent part' has any special meaning in 
>>>> these defs - we could drop it. The reasoner is right to throw up 
>>>> those "rhoptry lumen" relationships - they are dodgy, how can it be 
>>>> both a cell part and extracellular?
>>>>
>>>> Jane
>>>>
>>>> Chris Mungall wrote:
>>>>> We use the phrase "constituent part" in (almost) all the "X part" 
>>>>> terms; e.g.:
>>>>>
>>>>> axoneme part [DEF: "Any constituent part of an axoneme, the bundle 
>>>>> of microtubules and associated proteins that forms the core of 
>>>>> cilia and flagella in eukaryotic cells and is responsible for 
>>>>> their movements."]
>>>>>
>>>>> What exactly does "constituent" mean here?
>>>>>
>>>>> I recall being part of the discussion that lead to this, but can't 
>>>>> find the relevant emails. Did we just import this term from the 
>>>>> FMA? It seems to have a specific meaning in anatomy. I can't 
>>>>> really find a solid definition in the FMA papers.
>>>>>
>>>>> I don't see anything in the component docs either.
>>>>>
>>>>> I think we should either document this or drop it
>>>>>
>>>>> Here's why I'm interested - I define X part generically as a 
>>>>> cellular component that is part_of X.
>>>>>
>>>>> This means the reasoner throws up:
>>>>>
>>>>>     "rhoptry lumen" [GO:0034591] is_a "extracellular region part" 
>>>>> [GO:0044421]
>>>>>     "rhoptry lumen" [GO:0034591] is_a "cell part" [GO:0044464]
>>>>>
>>>>> Is there something subtle in the "constituent" qualifier that is 
>>>>> missing from my xp definition, that simultaneously excludes the 
>>>>> above links?
>>>>> _______________________________________________
>>>>> Ontology-editors mailing list
>>>>> Ontology-editors at geneontology.org
>>>>> http://fafner.stanford.edu/mailman/listinfo/ontology-editors
>>>>
>>>>
>>>> -- 
>>>> Dr Jane 
>>>> Lomax                                                               
>>>>                                            GO Editorial 
>>>> Office                                                              
>>>>                                       
>>>> EMBL-EBI                                                                 
>>>>                                               Wellcome Trust Genome 
>>>> Campus                                                              
>>>>                              
>>>> Hinxton                                                             
>>>>                                                    Cambridgeshire, 
>>>> UK                                                                  
>>>>                                    CB10 
>>>> 1SD                                                                 
>>>>                                                                     
>>>>                                                                     
>>>>                             p: +44 1223 
>>>> 492516                                                              
>>>>                                        f: +44 1223 494468
>>>>
>>>>
>>
>>
>> -- 
>> Dr Jane 
>> Lomax                                                                 
>>                                          GO Editorial 
>> Office                                                                
>>                                     
>> EMBL-EBI                                                                   
>>                                             Wellcome Trust Genome 
>> Campus                                                                
>>                            
>> Hinxton                                                               
>>                                                  Cambridgeshire, 
>> UK                                                                    
>>                                  CB10 
>> 1SD                                                                   
>>                                                                       
>>                                                                       
>>                       p: +44 1223 
>> 492516                                                                
>>                                      f: +44 1223 494468
>>
>>


-- 
Dr Jane Lomax                                                                                                          
GO Editorial Office                                                                                                    
EMBL-EBI                                                                                                               
Wellcome Trust Genome Campus                                                                                           
Hinxton                                                                                                                
Cambridgeshire, UK                                                                                                     
CB10 1SD                                                                                                               
                                                                                                                       
p: +44 1223 492516                                                                                                     
f: +44 1223 494468



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