[Ontology-editors] CC organization question for xps

Midori Harris midori at ebi.ac.uk
Mon Nov 17 02:51:40 PST 2008


Hi all,

I have a suggestion and question about the CC organization terms that are 
relevant to XPs ...

Several of us agreed recently that all cellular components are anatomical 
structures. For the xp set I'm looking at -- 
biological_process_xp_cellular_component.* -- I can put in more specific 
genus terms for several xp defs if I add the relationship:

GO:0022607 cellular component assembly is_a GO:0048646 anatomical 
structure formation

It might also be good (though less pressing for my xps) to add a parent in 
the anatomical structure branch of BP for GO:0016043 cellular component 
organization. I'm not sure whether GO:0048532 anatomical structure 
arrangement exactly fits the bill, though. The definitions don't quite 
match up, in that GO:0048532 is restricted to "the configuration of the 
constituent parts of an anatomical structure" and so covers only the 
"arrangement of constituent parts" part of the GO:0016043 def, not the 
formation or disassembly. (I also don't quite understand how GO:0048532 
can have 'structural organization' as an exact synonym when the more 
restricted phrase 'anatomical structure organization' is a broad synonym.)

GO:0022607 (and GO:0016043, if we decide on an anatomical structure 
process parent for it) will acquire a path back to GO:0032502 
developmental process. The definition GO uses for developmental process is 
broad enough to be consistent with the new paths, and it would be entirely 
consistent with our thinking about the CC organization terms, but some 
users may think it looks odd if they've been accustomed to thinking of 
'development' having a narrower meaning. I can live with that, but we 
should be prepared for questions.

Note that we already have GO:0032989 cellular structure morphogenesis is_a 
GO:0009653 anatomical structure morphogenesis.

Shall I go ahead and add GO:0022607 is_a GO:0048646?

m


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