[Ontology-editors] Cell fractions

Chris Mungall cjm at berkeleybop.org
Tue Feb 10 20:19:16 PST 2009


Following on from our call this morning - it seems the cell fraction  
terms may be around for a while yet. However, I was wondering what  
people's opinions were on evidence codes for fraction terms. I'm not  
really sure how valid it is to make an ISS to a fraction term. Or an  
IMP. Shouldn't IDA be the only code allowed?

Here are some IMPs for microsome:

http://amigo.geneontology.org/cgi-bin/amigo/term-assoc.cgi?gptype=all&speciesdb=all&taxid=all&evcode=IMP&term_assocs=all&term=GO%3A0005792&action=filter

I followed up the mouse one and am not really sure how the IMP is  
justified

Here are some numbers for the genes annotated to cell fractions using  
different evidence codes

>> +------------+--------------------------------------------- 
>> +--------------------+------+---------+
>> | acc        | name                                        |  
>> term_type          | code | n_genes |
>> +------------+--------------------------------------------- 
>> +--------------------+------+---------+
>> | GO:0000267 | cell fraction                               |  
>> cellular_component | IDA  |       3 |
>> | GO:0000267 | cell fraction                               |  
>> cellular_component | NAS  |       1 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | IDA  |      27 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | IPI  |       2 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | ISA  |       1 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | ISO  |       2 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | ISS  |      16 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | NAS  |       1 |
>> | GO:0000299 | integral to membrane of membrane fraction   |  
>> cellular_component | TAS  |       3 |
>> | GO:0000300 | peripheral to membrane of membrane fraction |  
>> cellular_component | IDA  |      28 |
>> | GO:0000300 | peripheral to membrane of membrane fraction |  
>> cellular_component | IPI  |       1 |
>> | GO:0000300 | peripheral to membrane of membrane fraction |  
>> cellular_component | ISA  |       1 |
>> | GO:0000300 | peripheral to membrane of membrane fraction |  
>> cellular_component | ISO  |       3 |
>> | GO:0000300 | peripheral to membrane of membrane fraction |  
>> cellular_component | ISS  |       6 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | IDA  |     615 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | IGI  |       1 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | IMP  |       5 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | ISA  |       4 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | ISO  |      19 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | ISS  |     280 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | NAS  |      17 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | RCA  |       2 |
>> | GO:0005624 | membrane fraction                           |  
>> cellular_component | TAS  |     249 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | IDA  |     428 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | IMP  |       2 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | ISA  |       1 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | ISO  |       8 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | ISS  |      99 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | NAS  |      10 |
>> | GO:0005625 | soluble fraction                            |  
>> cellular_component | TAS  |     135 |
>> | GO:0005626 | insoluble fraction                          |  
>> cellular_component | IDA  |      65 |
>> | GO:0005626 | insoluble fraction                          |  
>> cellular_component | ISO  |       1 |
>> | GO:0005626 | insoluble fraction                          |  
>> cellular_component | ISS  |      32 |
>> | GO:0005626 | insoluble fraction                          |  
>> cellular_component | TAS  |       5 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | IDA  |     240 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | IMP  |       5 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | IPI  |       3 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | ISA  |       2 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | ISO  |       4 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | ISS  |     105 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | NAS  |      97 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | RCA  |       1 |
>> | GO:0005792 | microsome                                   |  
>> cellular_component | TAS  |      40 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | IDA  |      77 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | IEP  |       1 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | ISA  |       1 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | ISO  |       5 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | ISS  |      34 |
>> | GO:0019717 | synaptosome                                 |  
>> cellular_component | NAS  |       2 |
>> | GO:0019718 | rough microsome                             |  
>> cellular_component | IDA  |       5 |
>> | GO:0019719 | smooth microsome                            |  
>> cellular_component | IDA  |       1 |
>> | GO:0042598 | vesicular fraction                          |  
>> cellular_component | IDA  |      12 |
>> | GO:0042598 | vesicular fraction                          |  
>> cellular_component | ISS  |       7 |
>> +------------+--------------------------------------------- 
>> +--------------------+------+---------+
>> 53 rows in set (36.97 sec)

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://fafner.stanford.edu/pipermail/ontology-editors/attachments/20090210/7ff112c9/attachment-0001.html>


More information about the Ontology-editors mailing list