[Ontology-editors] DASH complex - two part_of parents
Midori Harris
midori at ebi.ac.uk
Mon Feb 23 04:46:08 PST 2009
Hi,
This is just to record that Val and I have looked at the literature on the
DASH complex (GO:0042729), and agreed that it's OK for it to have two
part_of parents for now.
Background: the DASH complex term was originally added with two part_of
parents, GO:0000778 condensed nuclear chromosome kinetochore and
GO:0005828 kinetochore microtubule. It was duly flagged by Chris' QC
report, and at a meeting involving Jane, David and me, Jane created two
child terms to avoid true path violations. After that work we had:
DASH complex GO:0042729
[i] kinetochore-associated DASH complex GO:0043926
[i] microtubule-associated DASH complex GO:0043925
condensed nuclear chromosome kinetochore
[p] kinetochore-associated DASH complex GO:0043926
kinetochore microtubule
[p] microtubule-associated DASH complex GO:0043925
But Val and I confirmed that, as far as is known in the field, every DASH
complex that forms is part of a kinetochore and associated with
kinetochore microtubules. I think using a different relationship type,
perhaps associated_with or connected_to or adjacent_to, between DASH
complex and kinetochore microtubule would improve our representation of
the biology, but until we add new relationship types, allowing the
original DASH complex term to have two part_of parents is the most
biologically accurate thing we can do.
Accordingly, I've merged the newer terms into the parent, restoring the
part_of relationships (and removing the newer term names from the synonym
list -- looks like nobody uses them).
midori
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