[Ontology-editors] disrupting host processes

[Midori Harris]

Good question ... I don't think disruption is necessarily negative 
regulation. Overzealous positive regulation could also be pretty 
disruptive! And I agree about disruption not even necessarily being any 
sort of regulation.

I wonder if we could use a cross-product that includes a generic 
'disruption' term -- could use one of those anonymous classes if we don't 
want 'disruption' in GO otherwise ...

???
m

On Tue, 24 Feb 2009, Jane Lomax wrote:

> Hello - so here's an interesting question...I'm adding some new PAMGO terms, 
> one of which is 'disruption by symbiont of host system process'.
>
> We have a term under multicellular organism process 'system process'. I feel 
> that we need to make a relationship between 'disruption by symbiont of host 
> system process' and 'system process' - but what?
>
> Regulates - or perhaps negatively regulates - would seem the most likely, but 
> is that really quite right? If it were, for example, a tumor causing the 
> system disruption we wouldn't call that regulation would we?
>
> Jane
>
>